Found 4844 clinical trials
Diabetic Kidney Disease
combination of the two study medications is superior than one medication alone in reducing protein in the urine, therefore, helping to slow the progression of kidney disease.
- 0 views
- 26 Jan, 2023
- 1 location
Natural History Study of Monoclonal B Cell Lymphocytosis (MBL), Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma(CLL/SLL), Lymphoplasmacytic Lymphoma(LPL)/Waldenstrom Macroglobulinemia (WM), and Splenic Marginal Zone Lymphoma(SMZL)
methods in a natural history study can clarify processes involved in disease progression and possibly lead to the discovery or validation of treatment targets. Objectives:
- 115 views
- 15 Apr, 2019
- 1 location
EF-36/Keynote: A pilot, single arm, open-label study of Tumor Treating Fields (TTFields, 150 kHz) concomitant with pembrolizumab for first line treatment of advanced or metastatic intrathoracic non-small cell lung cancer
This is a multicenter, single arm, open-label study of Tumor Treating Fields (TTFields) at 150 kHz to the thorax using the NovoTTF-200T System concomitant with IV pembrolizumab (also known as MK-3475) in subjects previously untreated for their advance or metastatic intrathoracic, PD-L1 positive (TPS≥1% [tumor proportion score]) non-small cell lung …
- 0 views
- 29 Nov, 2022
- 1 location
A Pilot Phase II Study Using Ibrutinib and Short-Course Fludarabine in Previously Untreated Patients with Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL)
Background: Chronic lymphocytic leukemia (CLL) and/or small lymphocytic lymphoma (SLL) are tumors of abnormal B cells that often affect elderly patients. Studies have identified critical factors required for the growth of CLL cells. First, CLL cells survive because they receive signals through the B-cell receptor. Second, CLL cells benefit from …
- 169 views
- 15 Apr, 2019
- 1 location
Ibrutinib, Fludarabine, and Pembrolizumab in High-Risk or Relapsed/Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Background: Chronic lymphocytic leukemia (CLL) is a cancer of white blood cells. It is also called small lymphocytic lymphoma (SLL). It causes tiredness, night sweats, weight loss, swollen lymph nodes, easy bruising or bleeding, and frequent infections. Researchers want to test if a drug combination is effective and safe for …
- 359 views
- 23 Nov, 2020
- 1 location
HERV-E TCR Transduced Autologous T Cells in People With Metastatic Clear Cell Renal Cell Carcinoma
Gene transfer is a new cancer therapy takes white blood cells from a person and grows them in a lab. The cells are changed with a virus to attack tumor cells, then returned to the person. Researchers want to see if this therapy fights kidney cancer cells. Metastatic renal cell …
- 210 views
- 22 Dec, 2020
- 1 location
A Randomized Phase 3 Study of Sitravatinib in Combination with Nivolumab Versus Docetaxel in Patients with Advanced Non-Squamous Non-Small Cell Lung Cancer with Disease Progression On or After Platinum-Based Chemotherapy and Checkpoint Inhibitor Therapy (SAPPHIRE)
docetaxel in patients with advanced non-squamous NSCLC who have previously experienced radiographic disease progression on or after treatment with platinum-based chemotherapy in combination with CIT.
- 543 views
- 04 May, 2022
- 143 locations
Effect of Passive Immunization on the Progression of Mild Alzheimer’s Disease: Study Drug Versus Placebo
Effect of Passive Immunization on the Progression of Mild Alzheimer’s Disease: Study Drug Versus Placebo
- 59 views
- 08 Dec, 2020
- 1 location
Have you had a slow progression of memory decline in the last year or so?
Have you had a slow progression of memory decline in the last year or so?
- 388 views
- 08 Dec, 2020
- 1 location
Have you had a slow progression of memory decline in the last year or so?
Have you had a slow progression of memory decline in the last year or so?
- 92 views
- 08 Nov, 2020
- 1 location