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Found 26 clinical trials
Cost-utility and Physiological Effects of ACT and BATD in Patients With Chronic Pain and Depression

). Biomarkers: hair cortisol and cortisone, corticosteroid-binding globulin (CBG), ACTH and cortisol in plasma, and genotyping of 5 polymorphisms in the FKBP5 gene involved in the regulation of the

  • 26 Jan, 2021
  • 2 locations
SPI-62 as a Treatment for Hypercortisolism Related to a Benign Adrenal Tumor (ACSPIRE)

This will be a randomized, double-blind study to evaluate the efficacy, safety, and pharmacological effect of SPI-62 in subjects with hypercortisolism related to a benign adrenal tumor.

  • 23 Jul, 2022
  • 1 location
Effects of Tofacitinib vs Methotrexate on Rheumatoid Arthritis Interstitial Lung Disease (PULMORA)

Pulmonary abnormalities are present in up to 60% of patients with early rheumatoid arthritis (RA), and up to 10% of the patients will develop clinical interstitial lung disease (ILD). Recent data indicate that inhibition of Janus kinase is beneficial for this extra-articular manifestation. Our goal is to determine whether tofacitinib …

interstitial lung disease
  • 10 May, 2022
  • 1 location
Comparison of IntraArticular Platelet-Rich-Plasma to Corticosteroid Injections for Patients With Zygapophyseal Joint (Z-Joint) Low Back Pain Confirmed by Dual Intra-Articular Local Anesthetic Injections

Comparison of IntraArticular Platelet-Rich-Plasma to Corticosteroid Injections for Patients with Zygapophyseal Joint (Z-Joint) Low Back Pain Confirmed by Dual Intra-Articular Local Anesthetic Injections: A Triple Blinded Randomized Controlled Trial.

  • 22 Jul, 2022
The Effect of Propolis in Tinea Pedis Treatment: A Randomized Controlled Study

Tineapedis is an important health problem. Providing foot care in tinea pedis treatment contributes positively to the treatment. In addition, alternative treatments can also be used. In this study, the randomization study group will be divided into three. Medical treatment and foot care training will be applied to the first …

Accepts healthy volunteers
  • 26 Dec, 2021
  • 1 location
ZILRETTA for Treatment of Idiopathic Adhesive Capsulitis

Adhesive capsulitis is a fairly common orthopedic condition that causes pain and loss of range of motion. There are a variety of ways to treat adhesive capsulitis, one of them being an intra-articular steroid injection. This is done to help decrease the inflammatory response caused by adhesive capsulitis. In this …

  • 14 Apr, 2021
  • 1 location
Association of Peripheral Blood Immunologic Response to Therapeutic Response to Adjuvant Treatment With Immune Checkpoint Inhibition (ICI) in Patients With Newly Diagnosed Glioblastoma or Gliosarcoma

Background Glioblastoma (GBM) is a type of malignant glioma. These cancers are nearly always fatal. People who develop these cancers get aggressive treatments. But the tumors almost always recur. Researchers want to study people with newly diagnosed disease to learn more. Objective To study people with newly diagnosed GBM or …

malignant glioma
complete resection
platelet count
gross total resection
  • 20 Jul, 2022
  • 1 location
Focal Laser Ablation for the Treatment of Focal Low-Intermediate Risk Prostate Cancer

Short-term Efficacy of Transperineal Laser Ablation (TPLA) with Image Fusion and Multi-parametric (mpMRI) Follow-up in Focal Low-intermediate Risk Prostate Cancer. It is an interventional pilot study. The clinical evaluation will be carried out at different times as follows Time 0: recruitment and eligibility assessment (patient selection) Time 1: interview, signing …

multiparametric magnetic resonance imaging
biopsy of prostate
  • 14 Feb, 2022
  • 1 location
Noninvasive Brain Stimulation Training

Non-invasive cerebral stimulation techniques have shown potential in the treatment of neurological disorders such as chronic pain, Parkinson's disease, neglect, aphasia, memory, engine deficit and epilepsy In general, non-invasive cerebral stimulation techniques have been shown to be able to induce changes in cortical plasticity that may last even beyond the …

brain stimulation
neurological injury
  • 22 Jan, 2021
  • 1 location
Chocolate and Physical Exercise to Reduce Malnutrition in Pre-dementia Aged People (Choko-AGE)

We hypothesize that the antioxidant and cytoprotective functions of vitamin E combined with the cortisol-lowering effect of chocolate polyphenols and physical activity may help prevent the age-dependent decline of mitochondrial function and nutrient metabolism in skeletal muscle, key underpinning events in protein-energy malnutrition (PEM) and muscle wasting in the elderly. …

vitamin e
mini-mental state examination
mental state examination
mild cognitive impairment
  • 25 May, 2022
  • 1 location