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Found 387 clinical trials
The Role of Bacterial Toxins in Human Skin Disease

Atopic dermatitis and psoriasis are two skin diseases often associated with bacterial infections and inflammation. Studies indicate that skin cells from these patients may have some changes that make these patients more susceptible to bacterial infections. Inflammatory environment may have an effect on the function of skin cells. The purpose …

skin disorder
bacterial infection
elidel
antibiotics
antihistamines
  • 269 views
  • 23 Feb, 2022
  • 1 location
Inhaled Corticosteroid Withdrawal in Chronic Obstructive Pulmonary Disease (COPD)

According to the WISDOM study, withdraw of inhaled steroids has no effect on the acute exacerbation of chronic obstructive pulmonary disease (COPD), but the lung function of patients with COPD is significantly reclined. In the subgroup analysis of this study, patients with COPD were found to have continued to use …

bronchodilator
pneumonia
acute exacerbation of chronic obstructive pulmonary disease
inhaled steroids
pulmonary function test
  • 0 views
  • 24 Jan, 2021
  • 1 location
Using Specific Tests in Preschool Children With Wheeze to Help us Determine the Necessity of Inhaled Corticosteroid Therapy (Feasibility Study).

Wheezing is common in preschool children and affects quality of life. Although asthma treatments such as inhaled steroids (ICS), which reduce swelling (inflammation) in the airways are used in this age group, they are often ineffective. That is because only some preschool children have the type of inflammation (known as …

  • 0 views
  • 08 Dec, 2021
  • 1 location
Prospective Longitudinal Effects of Intra-articular Corticosteroid Injection on Synovial Fluid Oxygen (POLO)

Inflammatory arthritis such as rheumatoid arthritis (RA) and psoriatic arthritis (PsA) are characterized by synovial inflammation of joints, potentially leading to joint destruction and functional disability. Inflamed joints have lower oxygen levels. Studying how oxygen level within the joint affect inflammation may lead to new treatments for patients with arthritis. …

  • 0 views
  • 29 May, 2022
  • 1 location
Immune Response to SARS-CoV-2/COVID-19 Vaccination in Sarcoidosis

People with sarcoidosis, particularly those with significant lung and/or cardiac involvement, who become infected with severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) are likely at increased risk of complications or death from COVID-19. While SARS-CoV-2 vaccines are highly efficacious in preventing COVID-19 in the general population, whether vaccination provides similar protection in …

immunosuppressants
vaccination
Accepts healthy volunteers
mediators
  • 16 views
  • 14 Dec, 2021
  • 1 location
Corticosteroid Combining Noncorticosteroid Systemic Immunomodulatory Therapy in VKH

The aim of this study is to evaluate the efficacy and safety of corticosteroidcombining noncorticosteroid systemic immunomodulatory therapy (NCSIT) for the treatment of Vogt Koyanagi Harada disease (VKH).

prednisone
methotrexate
mycophenolate
cyclophosphamide
corticosteroids
  • 0 views
  • 25 Nov, 2021
  • 1 location
Correlation of Polymorphisms of Lipoprotein Lipase (LpL) and Apolipoprotein E (Apo E) With Lipid Profile of Children With Acute Lymphoblastic Eukaemia During Therapy With L - Asparaginase.

Haematological malignancies constitute the most common neoplastic disease in child population, with acute leukemia occupying the number one spot with a percentage of 32.8%. In children, leukaemia is primarily encountered in its acute form (97%) and in the majority of the cases it is presented as Acute Lymphoblastic Leukaemia - …

lymphoid leukemia
remission
cancer
acute leukemia
asparaginase
  • 0 views
  • 04 Mar, 2022
  • 1 location
To Assess the Management of Patients on Global Initiative of Asthma (GINA) Step 4 and 5 Treatment in Hong Kong

This study aims to prospectively assess the asthma control and management of asthma patients who are on step 4, 5 asthma of GINA in Hong Kong (on at least medium-dose ICS-LABA as controller therapy for asthma) and also observe their exacerbations over 2 years. In addition, this study will also …

  • 0 views
  • 07 Aug, 2021
  • 1 location
Atherosclerosis in Rheumatoid Arthritis and Lupus: Restoring Cholesterol Balance

Hypothesis: SLE and RA increase risk of myocardial infarction (MI, heart attack). Immune reactants in the circulation of SLE patients downregulate cholesterol efflux proteins 27-hydroxylase and ABCA1 and upregulate scavenger receptor CD36, thus encouraging cholesterol accumulation. Adenosine A2A receptor agonist or statin treatment of cells exposed to SLE plasma (or …

atherosclerosis
lupus
Accepts healthy volunteers
psoriatic arthritis
  • 40 views
  • 16 May, 2022
  • 1 location
LOng COvid COmorbidities: Andrological, Reproductive, Sexual Dysfunctions in Patients Recovered From COVID-19

Considering the compelling amount of studies focused on patients in the active phase of COVID-19 disease and the scarcity of studies focused on patient cured from disease aimed at evaluating the sequelae of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection, the purpose of the study is to investigate, in …

  • 0 views
  • 04 Jun, 2022
  • 1 location