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Found 393 clinical trials
Novel Method of Pancreatic Islet Transplantation Into the Omentum

The investigators propose to conduct a pilot clinical study in 10 type 1 diabetic subjects suffering from hypoglycemia unawareness syndrome and episodes of severe hypoglycemia, in which therapy with transplantation of allogeneic pancreatic islets would be indicated according to current criteria at the Institute for Clinical and Experimental Medicine (IKEM). …

  • 0 views
  • 05 Sep, 2021
  • 1 location
Evaluation of Ultrasound-guided Erector Spinae Plane Block for Postoperative Analgesia in Upper GI Laparoscopy Surgeries: A Prospective, Randomized, Controlled Clinical Trial

This study will help us in understanding the role of erector spinae block (ESPB) for postoperative pain control in patients undergoing upper GI laparoscopy surgeries. The surgeries included in this group include laparoscopic cholecystectomy, laparoscopic gastrectomy, laparoscopic umblical or epigastric hernia repair. Patients aged between 18 and 65 years, scheduled …

  • 0 views
  • 27 Dec, 2021
  • 2 locations
Effects on Coordination of Sucking, Swallowing and Breathing Process of a Valved Feeding System in Late-preterm Newborns. The Safe Oral Feeding Trial (SOFT) (SOFT)

Comparing with a randomized controlled trial two different feeding systems in two groups of late-preterm newborns for evaluating which is more efficient in promoting the coordination in the process of sucking-swallowing-breathing and better cardiorespiratory stability. The B-ESP group will be fed with a feeding system with a valved ergonomic teat; …

  • 0 views
  • 22 Sep, 2022
Pulsed Radiofrequency of Suprascapular Nerve and Shoulder Joint for Chronic Shoulder Pain

Background: The suprascapular nerve block is frequently used to treat chronic shoulder pain. The nerve blockade provides probably only a short-term relief, and more compelling approaches have been investigated. Pulsed radiofrequency stimulation of suprascapular nerve has been reported as safe and reliable method for pain treatment. However, formal efficacy study …

  • 0 views
  • 10 Feb, 2021
  • 1 location
A Phase 1, Three-Part, Open-Label, Parallel-Cohort Safety and Tolerability Study of Relugolix in Combination With Abiraterone Acetate Plus a Corticosteroid, Apalutamide, or Docetaxel With or Without Prednisone in Men With Metastatic Castration-Sensitive Prostate Cancer or Non-Metastatic or Metastatic Castration-Resistant Prostate Cancer

This study is being conducted to assess the safety and tolerability of relugolix with other agents approved for use in combination with androgen deprivation therapy (ADT) for a 12-week treatment period and an additional 40-week safety extension period in men with prostate cancer, either metastatic castration-sensitive prostate cancer (mCSPC) or …

  • 2 views
  • 22 Sep, 2022
  • 15 locations
UVA-1 for Treatment of Skin Tightening and Improvement of Hand Function in Scleroderma

UVA-1 has been reported to be beneficial to skin changes in scleroderma in several case reports and a few small studies. (Jacobe 2020) Interpretation of these reports has been difficult based on the small numbers of subjects involved and the non-blinded non-randomized nature of the reports. In a single controlled …

scleroderma
  • 0 views
  • 05 Jun, 2022
  • 1 location
Triple Therapy in Chronic Obstructive Pulmonary Disease (COPD) Participants (TETRIS)

), long-acting beta 2 agonists (LABA) and inhaled corticosteroids (ICS).

  • 0 views
  • 09 Jul, 2022
  • 1 location
COVID-19 Vaccine Response in Chronic Respiratory Conditions

The investigators will assess the antibody, T cell and B cell responses to SARS-CoV-2 vaccination before and every 3 months for 18 months after the initial vaccination or subsequent vaccinations (boosters) in adults and children including patients with chronic medical conditions.

Accepts healthy volunteers
  • 0 views
  • 19 Apr, 2022
  • 1 location
China Atopic Dermatitis Registry Study

This regestry study is aimed to characterize the medical care and drug treatment under real-life conditions among Chinese patients with moderate to severe Atopic Dermatitis who are not well controlled by topical therapies.

topical agents
  • 0 views
  • 01 Sep, 2021
  • 1 location
Research on Severe Asthma (RAMSES)

The French Society for Respiratory diseases (SPLF), through its Asthma and Allergy working group (G2A), wishes to set up a national cohort of severe asthma patients to describe this population and the use of step 4 and 5 treatment. This study also meets the demand for post - registration studies …

  • 13 views
  • 26 Feb, 2022
  • 1 location