Found 391 clinical trials
A Randomized Double-blind Placebo-controlled Parallel Group Study Assessing the Efficacy and Safety of Dupilumab in Patients With Allergic Fungal Rhinosinusitis (AFRS)
Primary Objective: To evaluate the ability of dupilumab to reduce the need for rescue therapy with systemic corticosteroids (SCS) or surgery of AFRS in patients with AFRS who
- 60 views
- 09 Nov, 2022
- 5 locations
Dupilumab in CRSsNP (Liberty CRSsNP ORION)
of dupilumab to reduce the incidence of participants with CRSsNP worsening/acute sinusitis who require treatment with antibiotics, systemic corticosteroids (SCS) or sinus surgery compared to placebo
- 20 views
- 09 Nov, 2022
- 9 locations
GRAVITAS-309: A Phase 3 Study of Itacitinib or Placebo in Combination With Corticosteroids as Initial Treatment for Chronic Graft-Versus-Host Disease
The purpose of this study is to assess the efficacy and safety of itacitinib in combination with corticosteroids as first-line treatment for moderate or severe chronic graft-versus-host disease
- 121 views
- 10 May, 2022
- 1 location
A Single-Cohort, Phase 2 Study of Ruxolitinib in Combination With Corticosteroids for the Treatment of Steroid-Refractory Acute Graft Versus-Host Disease
A Single-Cohort, Phase 2 Study of Ruxolitinib in Combination With Corticosteroids for the Treatment of Steroid-Refractory Acute Graft Versus-Host Disease
- 322 views
- 08 Dec, 2020
- 1 location
A phase III randomized, double-blind, placebo-controlled study to evaluate the safety and efficacy of lebrikizumab in patients with persistent moderate to severe atopic dermatitis that is inadequately controlled by topical corticosteroids
inadequately controlled by topical corticosteroids
- 202 views
- 08 Nov, 2020
- 1 location
Phase 3 Asthma study for adults with inadequately controlled Asthma.
Phase 3 Asthma study for adults with inadequately controlled Asthma.
- 266 views
- 23 Nov, 2020
- 1 location
A Phase 2 Double-Blind, Placebo Controlled Multi-Center Study to Evaluate the Efficacy and Safety of Tcelna in Subjects With Secondary Progressive Multiple Sclerosis
A Phase 2 Double-Blind, Placebo Controlled Multi-Center Study to Evaluate the Efficacy and Safety of Tcelna in Subjects With Secondary Progressive Multiple Sclerosis
- 204 views
- 08 Nov, 2020
- 1 location
A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of ABT-494 for Induction and Maintenance Therapy in Subjects With Moderately to Severely Active Ulcerative Colitis
A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of ABT-494 for Induction and Maintenance Therapy in Subjects With Moderately to Severely Active Ulcerative Colitis
- 290 views
- 25 Mar, 2021
- 1 location
Longitudinal Observational Study of Severe Asthma
Background: Asthma is a lung condition that causes difficulty breathing and decreased lung function. Some people with asthma have more severe disease symptoms. They may be less responsive to standard treatments such as steroids. Researchers want to compare severe asthmatics with mild or moderate asthmatics or people without asthma over …
- 30 views
- 22 Dec, 2020
- 1 location
A phase II study of Antineoplastons A10 And AS2-1 Private In Children With Primary Malignant Brain Tumors
A phase II study of Antineoplastons A10 And AS2-1 Private In Children With Primary Malignant Brain Tumors
- 159 views
- 08 Nov, 2020
- 1 location