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Found 254 clinical trials
Cooling to Help Injured Lungs (CHILL) Phase IIB Randomized Control Trial of Therapeutic Hypothermia in Patients With ARDS (CHILL)

Acute Respiratory Distress Syndrome (ARDS) is a serious condition that occurs as a complication of medical and surgical diseases, has a mortality of ~40%, and has no known treatment other than optimization of support. Data from basic research, animal models, and retrospective studies, case series, and small prospective studies suggest …

sepsis
acute respiratory distress
positive end expiratory pressure
covid-19
pneumonia
  • 0 views
  • 23 Oct, 2022
  • 11 locations
A Phase I/II Study of the Combination of Venetoclax, Ponatinib and Corticosteroids in Patients With Relapsed or Refractory Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia and Lymphoid Blast Phase Chronic Myelogenous Leukemia

This phase I/II trial studies the best dose of venetoclax when given together with ponatinib and dexamethasone and to see how well they work in treating participants with Philadelphia chromosome or BCR-ABL positive acute lymphoblastic leukemia or chronic myelogenous leukemia that has come back or does not respond to treatment. …

myeloid leukemia
dexamethasone
amylase
hemolysis
chronic myeloid leukemia
  • 61 views
  • 22 Oct, 2022
  • 1 location
Cardiac Sarcoidosis Multi-Center Prospective Cohort (CHASM-CS)

showed that missing the diagnosis of CS in these patients' leads to significant mortality and morbidity. There are no published clinical consensus guidelines on treatment of CS. Corticosteroid

  • 198 views
  • 19 Jun, 2022
  • 13 locations
Research on Severe Asthma (RAMSES)

The French Society for Respiratory diseases (SPLF), through its Asthma and Allergy working group (G2A), wishes to set up a national cohort of severe asthma patients to describe this population and the use of step 4 and 5 treatment. This study also meets the demand for post - registration studies …

  • 13 views
  • 26 Feb, 2022
  • 1 location
China Atopic Dermatitis Registry Study

This regestry study is aimed to characterize the medical care and drug treatment under real-life conditions among Chinese patients with moderate to severe Atopic Dermatitis who are not well controlled by topical therapies.

topical agents
  • 0 views
  • 01 Sep, 2021
  • 1 location
From Immune System Damage to Podocyte Cell Damage: Prospective Database and Biological Collection of Patients (Children and Adults) With MGLS and HSFP

diagnosis of corticosteroid sensitivity, corticosteroid dependence, or risk of recurrence of kidney disease after kidney transplantation. To our knowledge, no prospective studies have been designed to study

corticosteroids
hypoalbuminemia
kidney biopsy
minimal change disease
nephropathy
  • 0 views
  • 25 Jan, 2021
  • 2 locations
BIOlogics in Severe Nasal POlyposis SurvEy (BIOPOSE)

. So far, endoscopic sinus surgery remains the treatment of choice when the first line of medical treatment with corticosteroid has failed. During the last 15 years, several studies have shown

  • 0 views
  • 26 Apr, 2022
  • 1 location
Response Assessment in SB CD

activity indices. We will use this innovative approach of triangular phenotyping to address our central hypothesis that "Corticosteroid-free remission at 52 weeks after biologic therapy initiation is

  • 13 views
  • 21 Mar, 2022
  • 1 location
Natural History of Treated Neurocysticercosis and Long-Term Outcomes

cysticercosis may be eligible for this study. Participants will be hospitalized for 2 to 3 weeks and will take either praziquantel or albendazole by mouth for 2 weeks. They may receive a corticosteroid to

  • 116 views
  • 23 Oct, 2022
  • 1 location
Asthma: Phenotyping Exacerbations 3 (APEX3)

Exacerbations of asthma (asthma attacks) are very common in the UK. They are frightening for patients, expensive for the health service, and occasionally lead to avoidable deaths. Despite the obvious importance of asthma attacks, they remain poorly understood. Although some of the triggers for attacks are known, the resultant characteristics …

  • 0 views
  • 04 Oct, 2022
  • 1 location