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Found 41 clinical trials
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Longitudinal Observational Study of Severe Asthma

Background: Asthma is a lung condition that causes difficulty breathing and decreased lung function. Some people with asthma have more severe disease symptoms. They may be less responsive to standard treatments such as steroids. Researchers want to compare severe asthmatics with mild or moderate asthmatics or people without asthma over …

asthma
allergic asthma
asthmatic
  • 22 views
  • 22 Dec, 2020
  • 1 location
Efficacy and Safety of Benralizumab in EGPA Compared to Mepolizumab.

administered by subcutaneous (SC) injection in patients with relapsing or refractory EGPA on corticosteroid therapy with or without stable immunosuppressive therapy. All patients who complete the 52

asthma
eosinophilia
prednisone
mepolizumab
oral prednisolone
  • 21 views
  • 19 Sep, 2021
  • 81 locations
Efficacy of Oral Corticosteroid Therapy in Recurrent Paralyzes After Thyroidectomy

Thyroidectomy is a common surgical procedure in France. Recurrent paralysis is one of the main complications. Oral corticosteroid therapy are frequently used at a dosage of 1mg/kg for seven days

  • 0 views
  • 02 Feb, 2021
  • 1 location
Efficacy and Adverse Effect of Simvastatin Compare to Rosuvastatin in Systemic Lupus Erythematosus (SLE) Patients With Corticosteroid Therapy and High Low-Density Lipoprotein (LDL) Cholesterol Level

Early statin therapy in SLE patients that have high cholesterol level and other atherosclerosis risk should reduce atherosclerosis and coronary artery events in later course of disease. By the way, statin is used in restricted groups of rheumatologists due to awareness of side effects; myositis and hepatitis, that are frequently …

autoimmune disease
corticosteroids
myositis
  • 22 views
  • 07 Nov, 2020
  • 1 location
Low Dose of Hydrocortisone and Fludrocortisone in Adult Cardiogenic Shock.

The purpose of this randomized controlled trial is to evaluate the hemodynamic effect of low dose corticosteroid therapy (hydrocortisone and fludrocortisone) in the treatment of adult

congestion
pulmonary artery occlusion
oliguria
hypoperfusion
catecholamines
  • 2 views
  • 06 Aug, 2021
  • 37 locations
Leflunomide Associated With Topical Corticosteroids for Bullous Pemphigoid

Bullous pemphigoid (BP) is the most common blistering auto-immune disease of skin with an incidence estimated to 400 new cases per year. Topical corticosteroid therapy is considered the

  • 1 views
  • 07 Nov, 2020
  • 1 location
Ustekinumab for the Treatment of Relapse of Refractory Giant Cell Arteritis

patients with GCA will relapse during their follow-up. Thus, the vast majority of patients treated for GCA have at least one adverse event from corticosteroid therapy, which is the main source of morbidity

  • 0 views
  • 25 Jan, 2021
  • 1 location
Study of T Lymphocytes in Patients With Horton Disease

Giant-cell arteritis (GCA) is the most frequent vasculitis after 50 years. Corticosteroid therapy is the reference treatment for GCA. This treatment is highly effective but must be maintained

temporal artery biopsy
erythrocyte sedimentation rate
artery biopsy
tenderness
granulomatous inflammation
  • 1 views
  • 23 Jan, 2021
  • 1 location
Dexamethasone and the Prevention of Post-Extubation Airway Obstruction in Adults

of prospective trials involving adults and evaluating the benefits of corticosteroid therapy prior to extubation have been conducted. Studies regarding the efficacy of prophylactic

systolic blood pressure
pao2
oxygen saturation
intubation
  • 0 views
  • 07 Nov, 2020
  • 1 location
A Multicenter Phase 2 Single-arm Proof-of-concept Trial to Assess the Efficacy and Safety of Ustekinumab in Association With Prednisone for the Treatment of Non-infectious Severe Uveitis (NISU)

side effects of chronic corticosteroid therapy and better understanding of the mechanisms of autoimmune-mediated uveitis, the aim of the treatment for patients with noninfectious uveitis is steroid

  • 4 views
  • 22 Apr, 2021
  • 3 locations