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Found 15 clinical trials
Featured trial
New Approaches to Dementia Heterogeneity.

This study is looking for adults who have mild cognitive impairment, Alzheimer’s, or other forms of dementia. The study is also looking for people with normal cognition, as a comparison. The study is interested in the ways that brain function changes over time with the goal of improving the ability to diagnose …

cancer
stroke
amyotrophic lateral sclerosis
multiple sclerosis
heart disease
  • 160 views
  • 25 May, 2021
  • 1 location
Community Outreach for Palliative Engagement -- Parkinson Disease (COPE-PD)

The purpose of this study is to learn more about the effectiveness of palliative care training for community physicians and telemedicine support services for patients and carepartners with Parkinson's disease and Lewy Body Dementia (LBD) or related conditions and their care partners. Palliative care is a treatment approach focused on …

parkinsonism
atrophy
supranuclear palsy
Accepts healthy volunteers
parkinson's disease
  • 0 views
  • 10 May, 2022
  • 1 location
The Swedish BioFINDER 2 Study (BioFINDER2)

The Swedish BioFINDER 2 study is a new study that will launch in 2017 and extends the previous cohorts of BioFINDER 1 study (www.biofinder.se). BioFINDER 1 is used e.g. to characterize the role of beta-amyloid pathology in early diagnosis of Alzheimer's disease (AD) using amyloid-PET (18F-Flutemetamol) and A analysis in …

flutemetamol
mini-mental state examination
amyloid
amyloidosis
neurodegenerative disorders
  • 178 views
  • 25 Feb, 2022
  • 1 location
Longitudinal Multi-Modality Imaging in Progressive Apraxia of Speech

The study is designed to determine the relationship between structural and functional changes in the brain on imaging and progression of speech and language, neurological and neuropsychological features in patients with neurodegenerative apraxia of speech (AOS).

  • 19 views
  • 24 Jan, 2022
  • 1 location
The Effect of Adrenergic Blocker Therapy on Cardiac and Striatal Transporter Uptake in Pre-Motor and Symptomatic Parkinson's Disease

REM Behavior Sleep Disorder (RBD) is a sleep disorder causing people to 'act out' their dreams. A high percentage of individuals with idiopathic RBD (iRBD) are known to develop conditions affecting the neurons in the brain such as Parkinson's disease (PD). Based on the increased risk to develop PD, individuals …

antidepressants
metaiodobenzylguanidine
dopamine
early parkinson's
tremor
  • 64 views
  • 17 Sep, 2022
  • 1 location
Saliva and Extracellular Vesicles for Parkinson's Disease (RaSPiD)

Rehabilitation is crucial in the treatment of people with Parkinson's disease (PD) as it can ameliorate motor and non-motor impairments, improving their clinical profile and quality of life. Considering the complex biological processes occurring in PD brain, the identification of accessible and measurable biomarkers to monitor the events induced by …

Accepts healthy volunteers
  • 1 views
  • 21 Apr, 2022
  • 4 locations
PROgressive Supranuclear Palsy CorTico-Basal Syndrome Multiple System Atrophy Longitudinal Study UK (PROSPECT-M)

Progressive Supranuclear Palsy (PSP), Cortico-Basal Degeneration (CBD) and Multiple System Atrophy (MSA) are degenerative brain conditions for which there are currently no curative treatments. To aid the development of new treatment trials, there is a pressing need to develop better methods for diagnosing these conditions early, and to track disease …

parkinsonism
atrophy
mri brain
supranuclear palsy
brain mri
  • 505 views
  • 25 Jan, 2022
  • 1 location
Modifiable Variables in Parkinsonism (MVP)

We are trying to identify factors associated with improved quality of life and fewer PD symptoms. We are attempting to identify practices, beliefs, and therapies used by individuals who report excellent quality of life, few PD symptoms, and reduced rates of progression. After agreeing to participate, we will ask participants …

parkinson's disease
dementia
atrophy
parkinsonism
corticobasal degeneration
  • 282 views
  • 05 Apr, 2022
  • 1 location
Neurodegenerative Diseases Registry (NDD Registry)

progressive supranuclear palsy (PSP). Similarly, distinguishing AD from other dementia syndromes including frontotemporal dementia (FTD), dementia with Lewy Bodies (DLB), corticobasal degeneration (CBD) and

atrophy
parkinsonism
supranuclear palsy
alzheimer's disease
multiple system atrophy
  • 131 views
  • 26 Jan, 2022
  • 1 location
ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)

ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD) represents the formalized integration of ARTFL (U54 NS092089; funded through 2019) and LEFFTDS (U01 AG045390; funded through 2019) as a single North American research consortium to study FTLD for 2019 and beyond.

primary lateral sclerosis
amyotrophic lateral sclerosis
frontotemporal dementia
Accepts healthy volunteers
dementia
  • 236 views
  • 28 May, 2022
  • 23 locations