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Found 84 clinical trials
Usefulness of the Use of Co-registration Strategy With iFR in Long and/or Diffuse Coronary Lesions (iLARDI)

Randomized controlled trial to determinate if the physiological iFR pullback evaluation with Syncvision software (intervention group) could be useful in the reduction of stent length implanted, with the potencial benefit in terms of MACEs reduction at follow-up with respect to angiographic guiding of percutaneous coronary intervention (control group).

  • 0 views
  • 04 Oct, 2022
  • 1 location
Adenovirus Vascular Endothelial Growth Factor D (AdvVEGF-D) Therapy for Treatment of Refractory Angina Pectoris (ReGenHeart)

The purpose of the study is to evaluate the safety and efficacy of catheter mediated endocardial adenovirus-mediated vascular endothelial growth factor-D (AdVEGF-D) regenerative gene transfer in patients with refractory angina to whom revascularisation cannot be performed.

bypass graft
stenosis
angina pectoris
revascularisation
angiography
  • 6 views
  • 28 Feb, 2022
  • 2 locations
OCT Guided vs COmplete Pci in patieNts With sT Segment Elevation myocArdial infarCtion and mulTivessel Disease

STEMI patients with multivessel disease will be randomized to complete PCI versus PCI driven by high risk criteria of plaques evaluated with OCT

  • 0 views
  • 16 May, 2021
  • 6 locations
The Association Between Catheter-based Absolute Coronary Flow and Resistance and 15O-H2O Positron Emission Tomography Scan Based Absolute Myocardial Blood Flow in the Coronary Artery Territory

Aims To assess the correlation between absolute flow and resistance assessed by catheter-based thermodilution technique using CoroFlow-system and myocardial blood flow (MBF) measured by positron emission tomography (PET) and the tracer [15O] labeled water ([15O]H2O) (15O-H2O PET) To assess the correlation between impaired MBF measured with 15O-H2O PET and negative …

coronary disease
stenosis
angina pectoris
angiography
  • 0 views
  • 31 Jul, 2021
  • 1 location
COSIMA: COronary SInus Reducer for the Treatment of Refractory Microvascular Angina (COSIMA)

Patients with refractory microvascular angina fulfilling the predefined inclusion and exclusion criteria will be enrolled in this randomized trial. The primary objective is to investigate whether the proportion of patients reporting an improvement in Canadian Cardiovascular Society (CCS) angina class (≥2 classes) is different at six months after implantation of …

  • 0 views
  • 21 Apr, 2022
  • 1 location
Imaging vs. no Testing in Asymptomatic High-risk Diabetic Patients

The aim of our study was to evaluate 1- and 3-year outcome of alternative imaging strategies in asymptomatic high-risk diabetic patients: functional stress echocardiography combined with coronary flow reserve (CFR) and strain imaging, or computed tomography (CT) angiography with direct visualization of coronary arteries, and no testing at all.

angiography
hypertension
  • 0 views
  • 29 Aug, 2021
  • 1 location
A Pilot Study in Severe Patients With Takayasu Arteritis.

Takayasu arteritis (TAK) is a rare chronic inflammatory arteritis, which lacks an effective well-accepted intervention strategy. We classify TAK patients into 3 levels, including mild, moderate, and severe. And the biological agents tocilizumab and adalimumab are randomly prescribed in severe patients, to find out the relatively better treatment strategy, facilitating …

tocilizumab
adalimumab
  • 0 views
  • 01 Mar, 2022
  • 1 location
Efficiency of Methotrexate and Tofacitinib in Mild and Moderate Patients

Takayasu arteritis (TAK) is a rare chronic inflammatory arteritis, which lacks an effective well-accepted intervention strategy. Here we tried to classify TAK patients in 3 levels, including mild, moderate, and severe, and prescribe methotrexate and tofacitinib randomly in mild and moderate patients, to observe the relatively better treatment strategy, facilitating …

tofacitinib
methotrexate
  • 4 views
  • 01 Mar, 2022
  • 1 location
Register Kardialer Computertomographie

The aim of this Heidelberg Cardiac CT Registry (Register kardiale Computertomographie) is to assess the diagnostic and prognostic perfomance of cardiac CT exminations in a real-world patient population.

  • 0 views
  • 24 Jan, 2021
  • 1 location
Diagnostic and Prognostic Value of Cardiac Biomarkers for Early Coronary Bypass Occlusion in Patients Undergoing Coronary Revascularization

This study is to evaluate the correlation between hs-cTn level as cardiac biomarker for ischemia and early graft occlusion as assessed by CCT in patients undergoing coronary bypass surgery.

  • 0 views
  • 16 Jul, 2021
  • 1 location