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Found 84 clinical trials
Heart Disease of the Small Arteries in Women and Men

Women suffer disproportionately than men from Cardiac Syndrome X ( chest pain in the absence of flow limiting coronary artery stenosis). Coronary microvascular disease is hypothesized to mediate

ischemia
angina pectoris
angiography
coronary disease
heart disease
  • 11 views
  • 23 Jan, 2022
  • 1 location
Edoxaban Versus Edoxaban With antiPlatelet Agent In Patients With Atrial Fibrillation and Chronic Stable Coronary Artery Disease (EPIC-CAD)

This study evaluates the efficacy and safety of Edoxaban with the combination of edoxaban and antiplatelet in patients with stable CAD (coronary artery stenosis ≥50% on medical treatment or

revascularisation
arterial disease
coronary artery stenosis
atrial fibrillation
percutaneous coronary intervention
  • 51 views
  • 09 Jul, 2022
  • 12 locations
Timing of FFR-guided PCI for Non-IRA in STEMI and MVD (OPTION-STEMI)

Patients with STEMI (ST-segment elevation myocardial infarction) with multivessel disease which have PCI (percutaneous coronary intervention)-suitable non-IRA (infarct related artery) will be randomized to immediate complete revascularization group or staged revascularization group by 1:1 fashion. Non-IRA lesion which have equal or more than 70% diameter stenosis by visual estimation will …

  • 0 views
  • 24 Jul, 2022
  • 19 locations
Precise Procedural and PCI Plan (P4) (P4)

strategy (comparator). After identifying the presence of a significant coronary stenosis, the patient will be randomized either to CT- or IVUS-guided PCI groups. Both CT and IVUS-guided PCI will be

myocardial infarction
stable angina
angiography
revascularisation
chest pain
  • 0 views
  • 17 Jun, 2022
  • 2 locations
Addition of FFRct in the Diagnostic Pathway of Patients With Stable Chest Pain

Rationale: Patients with stable chest pain enter a diagnostic pathway where Coronary Computed Tomography Angiography (CCTA) is often the first line non-invasive test to detect coronary stenosis

angiography
ischemia
  • 0 views
  • 06 Jan, 2022
  • 1 location
Randomized Evaluation of Beta Blocker and Angiotensin Converting Enzyme Inhibitor (ACEI) /Angiotensin Receptor Blocker (ARB) Treatment in MINOCA Patients. (MINOCA-BAT)

Myocardial infarction with non-obstructive coronary arteries" (MINOCA) occurs in 5-10% of all patients with AMI. There are neither any randomized clinical trials in MINOCA patients evaluating effects of secondary preventive treatments proven beneficial in patients with classic AMI, nor any treatment guidelines. The primary objective of this multi-national, multi-center pragmatic …

  • 6 views
  • 17 Sep, 2022
  • 26 locations
Screening for Asymptomatic Coronary Artery Disease in Kidney Transplant Candidates (CARSK)

The Canadian Australasian Randomized Trial of Screening Kidney Transplant Candidates for Coronary Artery Disease (CARSK) will test the hypothesis that eliminating the regular use of non-invasive screening tests for CAD AFTER waitlist activation is not inferior to regular (i.e., annual) screening for CAD during wait-listing for the prevention of Major …

metastases
renal failure
kidney transplant
arteriopathy
coronary disease
  • 1 views
  • 02 Mar, 2022
  • 15 locations
GENOSS Coronary Stent Clinical Trial

This study aims to evaluate the efficacy and safety of abluminal biodegradable polymer ultrathin sirolimus-eluting stent (Genoss stent) as compared with a durable-polymer everolimus-eluting stent (Xience stent) in patients with coronary artery disease.

acute coronary syndrome
percutaneous coronary intervention
sirolimus
everolimus
coronary artery disease
  • 0 views
  • 28 Jul, 2022
  • 1 location
Interventional Strategy for Non-culprit Lesions With Major Vulnerability Criteria at OCT in Patients With ACS

The INTERCLIMA (Interventional Strategy for Non-culprit Lesions With Major Vulnerability Criteria Identified by Optical Coherence Tomography in Patients With Acute Coronary Syndrome) is a multi-center, prospective, randomized trial of optical coherence tomography (OCT)-based versus physiology-based (i.e. fractional flow reserve[FFR]/instantaneous Wave-Free Ratio[iFR]/resting full-cycle ratio[RFR]) treatment of intermediate (40-70% diameter stenosis at …

acute coronary syndrome
angiography
stenosis
  • 0 views
  • 06 Sep, 2021
  • 1 location
Safety and Cost-efficiëncy of New Imaging Techniques in Patients Suspected of Coronary Artery Disease (iCORONARY)

Yearly, 180 000 patients in the Netherlands are referred to a cardiologist with symptoms suspected of coronary artery disease (CAD). To assess this, multiple diagnostic tests are available. Non-invasive imaging tests, such as coronary CT-scan, are safe, relatively cheap and can effectively rule-out CAD. However, when CAD is present, coronary …

angina pectoris
angiography
coronary ct
stenosis
  • 0 views
  • 05 Jun, 2022
  • 1 location