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Found 1206 clinical trials
Less Invasive Detection and Treatment of Very Early Coronary Artery Disease in Patients With Diabetes Mellitus

This protocol focuses on the development of a noninvasive method of early coronary artery disease detection in diabetes. The overall hypothesis is that risk factors for the metabolic

metabolic syndrome
  • 15 views
  • 07 Nov, 2020
  • 1 location
Imaging and Physiology for Intermediate Left Main Stem Stenosis

The present research aims to determine the impact of stenoses in downstream vessels on the FFR and iFR measurements of left main coronary artery (LMCA) stenoses of intermediate severity as determined by coronary angiography. Anatomic metrics derived from intravascular imaging modalities of IVUS and optical coherence tomography (OCT) will also …

  • 0 views
  • 25 Jan, 2021
  • 1 location
Intracoronary Infusion of Mononuclear Cells Autologous Bone Marrow in Patients With Chronic Coronary Occlusion and Ventricular Dysfunction Previously Revascularized.

Clinical trial phase III, prospective, controlled, randomized, open. We hypothesize work that patients with chronic coronary occlusion and poor myocardial viability who failed to recover ventricular function after subjecting coronary revascularization with new techniques of recanalization, could achieve an improvement of ventricular function if given further regenerative treatment with mononuclear …

  • 33 views
  • 23 Jan, 2021
  • 3 locations
Hierarchical Treatment Based on Somatization Symptom Checklist

A comparative study is conducted on the patients with suspected coronary artery disease (CAD). The patient will undergo coronary angiography after a somatic symptom scale (SSS) survey is carried

  • 34 views
  • 24 Jan, 2021
  • 1 location
Melatonin on Coronary Artery Calcification

We planned to evaluate the effects of melatonin on progression of coronary artery calcification (CAC) in patients with moderate calcified coronary atherosclerosis.

  • 0 views
  • 22 Jan, 2021
  • 1 location
A Phase IIa Clinical Trial on TSG-01 in the Treatment of Chronic Heart Failure in Patients With Coronary Heart Disease.

is now being conducted in 5 hospitals in China. A total of 90 cases of CHF caused by coronary heart disease are included and randomly divided into three groups: high-dose, low-dose of TSG-01 and

beta blockers
edema
6-minute walk test
ejection fraction
diuretics
  • 5 views
  • 25 Jan, 2021
  • 5 locations
Transplantation of Autologously Derived Mitochondria Following Ischemia

The investigators propose a robust therapeutic intervention to ameliorate myocardial ischemia/ reperfusion injury and significantly decrease morbidity and mortality in patients requiring

  • 0 views
  • 25 Jan, 2021
Safety and Efficacy Study of the SoundBite Crossing System With ACTIVE Wire in Coronary CTOs.

The objective of this study is to evaluate the safety and efficacy of the SoundBite Crossing System - Coronary (SCS-C) in a subject population with chronic coronary artery disease including

  • 26 views
  • 25 Jan, 2021
  • 7 locations
Evaluation of a New Nanotechnology Based Drug-Eluting Stent for Opening of Narrowed Arteries of the Heart

Coronary artery disease (CAD) is the largest cause of death and disability in the world. Besides medicines, the principle treatment of this condition requires opening of the narrowed

angina pectoris
diabetes
angiography
chest pain
ischemia
  • 24 views
  • 07 Nov, 2020
  • 1 location
Apabetalone for Pulmonary Arterial Hypertension: a Pilot Study

and that BRD4 inhibition can reverse PAH in several animal models. Intriguingly, coronary artery disease (CAD) and metabolic syndrome are more prevalent in PAH compared with the global population

hypertension
prostanoids
bosentan
pulmonary disease
serum pregnancy test
  • 8 views
  • 25 Jan, 2021
  • 3 locations