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Found 25 clinical trials
RNA Disruption Assay (RDA)-Breast Cancer Response Evaluation for Individualized Therapy

The current study aims to provide validation results of RNA Disruption Assay (RDA) as a tumour response assessment tool that uses tumour core biopsies taken starting from 35 +/- 4 days after the initiation of neoadjuvant chemotherapy.

invasive breast cancer
breast cancer
adjuvant therapy
cancer
  • 28 views
  • 28 May, 2021
  • 36 locations
Letrozole in Post-Menopausal Patients With Operable Hormone-Sensitive Breast Cancer

A short pre-surgical non-therapeutic trial involving postmenopausal women with newly diagnosed eR+, HeR2-negative operable breast cancers. After undergoing a core needle biopsy for tissue

breast cancer
lumpectomy
letrozole
invasive breast cancer
tamoxifen
  • 6 views
  • 13 May, 2021
  • 1 location
The MONET - Study: MR Mammography of Nonpalpable Breast Tumors

The purpose of this study is to determine whether performing MRI of the breast will improve breast cancer management by reducing the number of biopsies and in case of malignancy allowing one-stage surgical excision of the tumor.

breast cancer
cancer
core needle biopsy
  • 4 views
  • 07 Nov, 2020
  • 1 location
Study of Neoadjuvant Chemotherapy Plus Trastuzumab and Pertuzumab in HER2-Negative Breast Cancer Patients With Abnormal HER2 Signaling

This is a prospective, single arm, open label, multicenter interventional study designed to evaluate the efficacy of neoadjuvant chemotherapy with anti-HER2 antibodies in patients with HER2-negative invasive breast cancer who have abnormal HER2 signaling activity determined by the Celcuity CELx HER2 Signaling Function (HSF) testing.

immunohistochemistry
progesterone receptor
progesterone
probe
neutrophil count
  • 8 views
  • 21 Apr, 2021
  • 42 locations
Targeted Biopsy of Carbon Nanoparticles Labelled Axillary Node for cN+ Breast Cancer

To explore the feasibility of target biopsy of carbon nanoparticles labelled lymph node after neoadjuvant systemic therapy for cN+ breast cancer, and evaluate whether it can accurately predict axillary lymph node status after neoadjuvant systemic therapy.

  • 0 views
  • 30 Jan, 2021
  • 1 location
Enhanced Bioscaffold for Volumetric Muscle Loss

This is a prospective, single center study conducted at the University of Pittsburgh designed to test the applicability and utility of XenMatrix AB Surgical Graft in the restoration of function in the setting of volumetric muscle loss after soft tissue trauma.

  • 0 views
  • 27 Jan, 2021
  • 1 location
Study of Core Needle Biopsy and Cryoablation of an Enlarging Tumor in Patients With Metastatic Lung Cancer and Metastatic Melanoma Receiving Post-progression Immune Checkpoint Inhibitor Therapy

This research study is studying cryoablation (a treatment to kill cancer cells with extreme cold) combined with continued treatment with current immune checkpoint inhibitor as a possible treatment for lung cancer.

spiral computed tomography
measurable disease
x-rays
cancer
lung carcinoma
  • 3 views
  • 05 Mar, 2021
  • 1 location
  • 10 views
  • 26 Jul, 2021
  • 20 locations
Imipramine on ER+ve and Triple Negative Breast Cancer

Comparing changes in biomarkers from a diagnostic core needle biopsy to surgical pathology specimen or repeat core needle biopsy.

triple negative breast cancer
lobular carcinoma
ductal carcinoma
core needle biopsy
carcinoma
  • 0 views
  • 22 Aug, 2021
  • 1 location
Axillary Lymph Node Tattoo Marking Study

> Core needle biopsy and/or fine needle aspiration Surgical Removal of the Lymph Nodes via clip and radioseed guidance

core needle biopsy
  • 0 views
  • 18 Sep, 2021
  • 1 location