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Found 42 clinical trials
Beta-blockers to Patients With Chronic Obstructive Pulmonary Disease

known cardiovascular disease, systolic blood pressure < 90, severe asthma, present beta-blocker therapy or ongoing COPD exacerbation. Intervention: Metoprolol at a target dose of 100 mg in

copd exacerbation
pulmonary function test
respiratory symptom
  • 18 May, 2022
  • 1 location
Video Telehealth Pulmonary Rehabilitation to Reduce Hospital Readmission in Chronic Obstructive Pulmonary Disease

The purpose of this study is to compare the efficacy and safety of a real time video telehealth pulmonary rehabilitation intervention with standard of care in patients hospitalized for an exacerbation of chronic obstructive pulmonary disease (COPD) to determine the impact on hospital readmissions and respiratory morbidity, and to investigate …

  • 04 Oct, 2022
  • 5 locations
Roflumilast or Azithromycin to Prevent COPD Exacerbations (RELIANCE) (RELIANCE)

A multi-center, randomized, 72-month, parallel- group, non-inferiority, phase III study to compare the effectiveness of roflumilast (Daliresp, 500 mcg quaque die (QD) or alternate regimen) therapy versus azithromycin (250 mg QD, 500 mg QD three times per week, or alternate regimen) to prevent hospitalization or death in a patients at …

pulmonary disease
  • 09 Apr, 2023
  • 27 locations
Virtual Reality in COPD Exacerbation

In addition to conventional pulmonary rehabilitation, virtual reality will be applied during the hospitalization period of individuals hospitalized for COPD exacerbation. It is aimed to get more

  • 09 Apr, 2023
  • 1 location
Copd Exacerbation and Pulmonary Hypertension Trial

This trial will investigate whether patiens admitted with an acute exacerbation of chronic obstructive lung disease and pulmonary hypertension will benefit from a targeted pharmacological treatment.

  • 12 Aug, 2021
  • 5 locations
Testing a Prediction Algorithm Into a Running Telehealth System for Patients With COPD

This trial will test a COPD prediction algorithm into a telehealth system from the previous Danish large-scale trial, TeleCare North (NCT01984840). The COPD prediction algorithm aims to support clinical decisions by predicting exacerbations in patients with COPD based on selected physiological parameters (blood pressure, oxygen saturation, and pulse). A prospective, …

  • 23 Mar, 2022
  • 1 location
Treatment of Pneumocystitis in COPD (the TOPIC Study)

Chronic obstructive pulmonary disease (COPD) is a progressive lung disease associated with chronic inflammation in the airways and lung, resulting in significant morbidity and mortality worldwide. Smoking is the primary risk factor for development of COPD and progression of the disease is associated with acute exacerbations of COPD (AECOPD) that …

  • 13 Oct, 2022
  • 1 location
A Study to Evaluate the Efficacy and Safety of Sitafloxacin in Adult Subjects With Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Chronic obstructive pulmonary disease (COPD) is a common, preventable, and treatable disease, that causes obstructed airflow from the lungs that causes persistent obstructive airflow limitation. Acute exacerbation, especially frequent exacerbation, is associated with an increased risk of death in COPD patients. The most common causes of acute attacks are viral …

  • 11 Apr, 2023
  • 12 locations
Effectiveness of Low-Dose Theophylline for the Management of Biomass-Associated COPD

Chronic obstructive pulmonary disease (COPD) is the fourth leading cause of death worldwide, and over 90% of COPD-related deaths occurring in low- and middle-income countries (LMICs). Household air pollution (HAP) - from burning solid fuels such as wood, dung, agricultural crop waste, and coal for energy - is the primary …

  • 09 May, 2022
  • 1 location
Respiratory Support in Chronic Obstructive Pulmonary Disease (COPD) Patients

The hypothesis of this study is that any of 3 modalities of home non- invasive ventilation (NIV) compared to 'no NIV' (=hospital NIV) will reduce re-admission to hospital or death in COPD patients who remain persistently hypercapnic following an exacerbation requiring NIV.

pulmonary disease
forced expiratory volume
  • 12 Feb, 2022