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Found 141 clinical trials
Effect of Huaier Granule on Adjuvant Treatment for High-risk Early-stage Triple-negative Breast Cancer

This is a prospective, multicenter, randomized, parallel controlled, open-label study. The primary purpose of this study is to evaluate the efficacy of Huaier Granule on postoperative adjuvant therapy of high-risk early-stage triple-negative invasive ductal carcinoma. The Secondary purposes are to evaluate the safety of long-term use of Huaier granules as …

tumor cells
ductal carcinoma
  • 29 Jul, 2021
  • 1 location
To Reduce the Use of Chemotherapy in Postmenopausal Patients With ER-positive and HER2-positive Breast Cancer (TOUCH)

This is a phase II open-label, multicentre, randomized trial. The study assesses the treatment of postmenopausal patients with hormone receptor positive/HER2 positive early breast cancer with neoadjuvant palbociclib in combination with hormonal therapy and HER2 blockade, versus the treatment with paclitaxel in combination with HER2 blockade.

primary tumor
  • 17 Sep, 2021
  • 63 locations
Image Based Brachytherapy in Locally Advanced Cervical Cancers - a Randomized Controlled Trial

Purpose of the study is to determine whether Image based brachytherapy is superior in terms of local control to Conventional radiograph based brachytherapy in locally advanced cervical cancers in a Phase III randomized setting.

squamous cell carcinoma
cervical disease
  • 22 Jan, 2021
  • 1 location
Advanced Recovery Room Care II - Improved Recovery After Surgery

Moderate-risk surgical patients have a very high incidence of early serious postoperative complications (approximately 50% at Royal Adelaide Hospital, RAH). This affects patients' wellbeing and produces a high rate of unplanned postoperative hospital re-admissions. This is also costly, and patients unnecessarily fill approximately 4000 RAH bed days annually. A trial …

  • 28 Jun, 2021
  • 1 location
Comparison Between the Effect of Ultrasound Debridement and Conventional Treatment in Diabetic Foot Ulcers (DFU).

The investigators aimed to elucidate the effects of ultrasound debridement on the area and healing of diabetic foot ulcers compared to their conventional treatment.

  • 08 May, 2021
  • 1 location
Early Valve Surgery Versus Conventional Treatment in Infective Endocarditis Patients With High Risk of Embolism

Infective endocarditis (IE) is associated with an overall in-hospital mortality rate of 15-25% and a high incidence of embolic events (20-50%). Leading causes of mortality are heart failure (HF) resulting from valve dysfunction, and stroke caused by vegetation embolization. The rate of symptomatic embolic events occurring after antibiotic initiation is …

  • 06 Mar, 2021
  • 1 location
Randomized Clinical Trial Conventional Treatment-controlled Studying the Efficacy of Plasma Rich in Growth Factor (PRGF ) in Alveolar Ridge Preservation After Simple Exodontia in the Anterior Region of Maxilla.

This RCT aims to study the efficacy and safety of PRGF-Endoret in alveolar ridge preservation in the aesthetic zone. The control group is the spontaneous healing occuring after the suturing of the alveolus. The primary endpoint is the bone regeneration measured in biopsies obtained from the regenerated alveolar bone.

conventional treatment
periodontal disease
growth factor
  • 20 Sep, 2021
  • 4 locations
Effect of MUSK Pill on the Patients With Chest Pain Due to Non Obstructive Coronary Artery Disease

placebo 4 pills / day, 3 times / day on the basis of conventional treatment until the end of follow-up, while the experimental group was treated with MUSK Pill 4 pills / day, 3 times / day on the basis of

artery disease
chest pain
angina pectoris
  • 30 May, 2021
  • 1 location
Meridian Energy Changes of Head and Neck Cancer Patients After Chemotherapy or Radiotherapy

This trial is conducted by using MEAD to detect the meridian changes in patients with head and neck cancer after conventional treatment of chemotherapy or radiotherapy.

  • 10 May, 2021
  • 1 location
Efficacy and Safety of Intravitreal Triamcinolone Acetonide in Eyes With Post Vitrectomy Diabetic Vitreous Hemorrhage

The Purpose of this study is compare the efficacy of intravitreal triamcinolone in clearing recurrent post-vitrectomy diabetic hemorrhage with conventional treatment, air-fluid exchange.

  • 07 Nov, 2020
  • 1 location