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Found 142 clinical trials
Study Using Negative Pressure to Reduce Apnea (SUPRA) (SUPRA)

spontaneously breathing adult subjects who are intolerant of Continuous Positive Airway Pressure (CPAP) therapy.

obstructive sleep apnea
body mass index
polysomnography
  • 3 views
  • 11 Oct, 2022
  • 14 locations
LISA in the Delivery Room for Extremely Preterm Infants (DRLISA)

72 hours compared to the standard approach of stabilization on nasal CPAP in the DR and administering surfactant in the NICU. Infants in both groups will be resuscitated per NRP algorithm

  • 0 views
  • 09 Jul, 2022
  • 1 location
Impact of Extended CPAP Utilization on Bronchopulmonary Dysplasia in Extremely Premature Infants: A Pilot Randomized Control Trial

The purpose of this pilot study is to compare if keeping infants on CPAP (continuous positive airway pressure) support for an extended period of time until they are 32 weeks corrected

Accepts healthy volunteers
  • 0 views
  • 27 Oct, 2022
  • 1 location
A Randomized, Double-blind, Placebo-controlled, Multicenter Clinical Study to Evaluate the Efficacy and Safety of Pitolisant in the Treatment of Excessive Daytime Sleepiness in Patients With Obstructive Sleep Apnea

patients with Obstructive Sleep Apnea (OSA) not tolerating or refusing the nasal Continuous Positive Airway Pressure (nCPAP) therapy or treated by nCPAP but still complaining of EDS.

  • 0 views
  • 23 Oct, 2022
A Cardiosleep Research Program on Obstructive Sleep Apnea Blood Pressure Control and Maladaptive Myocardial Remodeling

The objective of this proposal is to evaluate whether mandibular advancement device (MAD) is non-inferior to continuous positive airway pressure (CPAP) in the treatment of obstructive sleep

mandibular advancement
chronic kidney disease
oral appliances
stroke
continuous positive airway pressure
  • 1 views
  • 21 Feb, 2021
  • 1 location
The Role of the Device Operating Under the Continuous Positive Airway Pressure in the Recovery Process of Cochlea

apnea; and then to prove that the use of a of continuous positive airway pressure with constant oxygen pressure in patients with OSAS using CPAP devices leads to the recovery of the cochlear receptor

Accepts healthy volunteers
  • 0 views
  • 04 Oct, 2022
  • 1 location
Mild Intermittent Hypoxia and Its Multipronged Effect on Sleep Apnea

laboratory's mandate to develop innovative therapies to treat sleep apnea, this increased stability could ultimately reduce the continuous positive airway pressure (CPAP) required to treat obstructive sleep

hypoxia
spinal cord disorder
oximetry
neurologic findings
hypertension
  • 128 views
  • 23 Aug, 2021
  • 2 locations
Delayed Cord Clamping With Oxygen In Extremely Low Gestation Infants (DOXIE)

CPAP/PPV with an FiO2 of 1.0 during DCC for 90 seconds (HI Group) to infants given mask CPAP/PPV with an FiO2 of .30 during DCC for 90 seconds (LO Group).

oximetry
FIO2
  • 0 views
  • 07 Oct, 2022
  • 2 locations
Phenotyping Mechanistic Pathways for Adverse Health Outcomes in Sleep Apnea

Obstructive sleep apnea (OSA) is a highly prevalent disorder with adverse neurocognitive and cardio-metabolic outcomes. Continuous positive airway pressure (CPAP) is the gold standard

sleep fragmentation
obstructive sleep apnea
apnea-hypopnea index
continuous positive airway pressure
  • 32 views
  • 20 Dec, 2021
Combination Drug-Therapy for Patients With Untreated Obstructive Sleep Apnea

Obstructive sleep apnea (OSA) is common and associated with many adverse health consequences, but many patients are unable to tolerate standard therapies such as continuous positive airway

  • 4 views
  • 01 Oct, 2021
  • 2 locations