Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 142 clinical trials
Featured trial
Impact of sleep apnea and its treatment on memory and tau accumulation in the brain

The purpose of the research study is to address whether obstructive sleep apnea (OSA) represents a risk factor contributing to the development of Alzheimer’s disease (AD) that can be slowed by treatment with Positive Airway Pressure (PAP). Our preliminary data shows conversion to Mild Cognitive Impairment in self-reported PAP users …

mild cognitive impairment
cognitive impairment
mini-mental state examination
amyloid
  • 0 views
  • 25 Mar, 2022
  • 1 location
Featured trial
Role of Slow Waves and Sleep Apnea in Memory and Risk for Alzheimer's Disease

take part in this research study because you have severe sleep apnea and have proven that you have used your CPAP (Continuous Positive Airway Pressure) machine consistently over the last two (2) months

  • 4 views
  • 25 Mar, 2022
  • 1 location
Featured trial
Drug Treatment Option for Sleep Apnea

Do you have trouble tolerating a CPAP or BiPAP for the treatment of your Obstructive Sleep Apnea (OSA)? If you do check out this study. At Intrepid, we are currently investigating a drug

apnea
somnolence
  • 14 views
  • 07 Mar, 2022
  • 1 location
Featured trial
Inspire® Upper Airway Stimulation System (UAS): Post-Approval Study

Inspire® Upper Airway Stimulation System (UAS): Post-Approval Study

  • 1874 views
  • 25 Mar, 2021
  • 1 location
A Physiological Study to Assess Awake Prone Positioning and Respiratory Support in Healthy Volunteers

continuous positive airway pressure (CPAP) was superior to HFNC and conventional oxygen therapy in reducing intubation rate. Thus, it is essential to evaluate the physiological mechanism of APP under

Accepts healthy volunteers
  • 0 views
  • 07 Oct, 2022
  • 1 location
Effectiveness of Combining Behavioral and Pharmacologic Therapy for Complex Insomnia in Veterans With PTSD (PRECEPT-D)

nightmares. Continuous positive airway pressure (CPAP) is the most effective therapy but adherence to treatment is suboptimal. Insomnia is considered a barrier to long-term adherence. The overarching theme

  • 64 views
  • 20 Feb, 2022
  • 1 location
The Efficacy of Continuous Positive Airway Pressure in Achieving Asthma Control in Patients With Severe Asthma and Obstructive Sleep Apnea

, titration of CPAP pressure will be performed by conventional polysomnography or using auto-CPAP equipment using a validated protocol. The investigators aim in this study to examine the effect of CPAP

Accepts healthy volunteers
  • 0 views
  • 04 Oct, 2022
  • 1 location
Muscle Strength Exercise and Sleep Apnea

, age, male gender, menopause, small jaw, sedative medications / drugs and alcohol. The most important treatment for sleep apnea is continuous positive airway pressure (CPAP). However, not all patients

dyspnea
obstructive sleep apnea
sedative
continuous positive airway pressure
  • 10 views
  • 23 Apr, 2022
A Dose-Ranging Study to Determine the Efficacy, Safety and Tolerability of AeroFact

The purpose of this two-part Phase 2 study is to assess the safety, tolerability and efficacy of aerosolized SF-RI 1 (AeroFact) when delivered via nCPAP at two different doses.

  • 96 views
  • 11 Mar, 2022
  • 29 locations
Alcohol and Neural Cardiovascular Control in Binge Drinkers

This study evaluates the impact of evening alcohol consumption on sympathetic activity and baroreflex function in binge drinkers. Our central hypothesis is that evening binge alcohol consumption will lead to sympathetic overactivity and blunted baroreflex function.

Accepts healthy volunteers
  • 13 views
  • 20 Apr, 2022
  • 1 location