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Found 225 clinical trials
Efficacy and Safety of Plecanatide Comparing With Placebo in the Treatment of Functional Constipation

This is a multi-center, randomized, double-blind, Placebo-controlled Phase III clinical study to evaluate the efficacy and safety of Plecanatide in the treatment of Functional Constipation in

  • 0 views
  • 08 Jun, 2022
  • 1 location
Evaluation of Clinical Equivalence Between Two Linaclotide Products in the Treatment of Chronic Idiopathic Constipation

Constipation, and to evaluate the efficacy and safety of the test formulation of Linaclotide in the treatment of Chronic Idiopathic Constipation.

  • 0 views
  • 27 Mar, 2021
  • 1 location
Effect of Lactulose and/or Polyethylene Glycol Solution for Bowel Preparation for Colonscopy Procedures

fact, no laxative has all the characteristics of an ideal medication. Lactulose is an osmotic laxative which widely used in cirrhosis and constipation patients, and could inhibit bacterial in the colon

Accepts healthy volunteers
  • 0 views
  • 21 Oct, 2021
  • 1 location
Defecation Patterns in Constipated Patients

Chronic constipation (CC) is a common condition that affects up to 25% of the population in North America. It poses a major burden on the healthcare cost. The pathophysiology of this condition

Accepts healthy volunteers
  • 0 views
  • 27 Jun, 2022
  • 1 location
Magnetic Resonance Imaging in Paediatric Constipation (MAGIC2)

Constipation in children is a common problem. Managing these children is difficult, partly because they do not respond to laxatives and partly because their bowel problem cannot be defined. A

constipation in children
laxative
other laxatives
  • 0 views
  • 24 Oct, 2021
  • 1 location
Laxative Properties of Microencapsulated Lipid (Constipation Study)

The present study seeks to build on these observations to assess whether in principle, fat containing microcapsules might help patients experiencing constipation in association with weight loss

lactulose
other laxatives
Accepts healthy volunteers
laxative
chronic constipation
  • 13 views
  • 13 Jun, 2022
  • 1 location
Use of a Squatting Assist Device in Patients With Constipation

Constipation is a very common problem. Western style toilets that are nearly universal in the United States require the person to sit on the toilet. However, results from uncontrolled studies

evacuations
functional constipation
irritable bowel syndrome
  • 23 views
  • 23 Feb, 2022
  • 1 location
The Inside Study: Oligosaccharides Versus Placebo in Functional Constipation (Inside)

children with functional constipation.

dietary intervention
change in stool consistency
  • 2 views
  • 28 Feb, 2022
  • 1 location
Methylnaltrexone vs Naloxegol in the Treatment of Opioid-Induced Constipation

The purpose of this study is to compare the efficacy of subcutaneous versus oral mu-opioid receptor antagonist therapy in opioid induced constipation that is refractory to other bowel regimens

  • 14 views
  • 10 Apr, 2022
  • 1 location
Understanding Mechanisms of Normal and Disordered Defecation

Researchers are trying to better understand why constipation occurs and improve the tests for diagnosing these conditions.

evacuations
Accepts healthy volunteers
chronic constipation
  • 90 views
  • 27 Feb, 2022
  • 1 location