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Found 56 clinical trials
Treating Patients With Childhood Acute Myeloid Leukemia With Interleukin-2

induction and consolidation chemotherapy concerning the event free survival.

remission
myeloid leukemia
  • 14 views
  • 07 Nov, 2020
  • 1 location
Study of Crenolanib vs Midostaurin Following Induction Chemotherapy and Consolidation Therapy in Newly Diagnosed FLT3 Mutated AML

A phase III randomized multi-center study designed to compare the efficacy of crenolanib with that of midostaurin when administered following induction chemotherapy, consolidation chemotherapy

  • 8 views
  • 25 Jan, 2021
  • 26 locations
Combination Chemotherapy With or Without Peripheral Stem Cell Transplantation Radiation Therapy and/or Surgery in Treating Patients With Ewing's Sarcoma

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Peripheral stem cell transplantation may allow the doctor to give higher doses of chemotherapy and kill more tumor cells. It is …

dactinomycin
etoposide
busulfan
tumor cells
cancer chemotherapy
  • 410 views
  • 07 Nov, 2020
  • 4 locations
The Randomised Study of Preoperative Radiotherapy With Consolidating Chemotherapy for Unresectable Rectal Cancer

The addition of Oxaliplatin to conventionally fractionated chemoradiation (FULV or capecitabine) is considered as standard in unresectable rectal cancer by the panel of experts. The Investigators addressed the question whether short-course preoperative radiotherapy with consolidating chemotherapy of FOLFOX4 may increase the rate of R0 resection in patients with unresectable rectal …

chemoradiotherapy
oxaliplatin
capecitabine
metastasis
  • 1 views
  • 07 Nov, 2020
  • 1 location
Induction Chemotherapy Radiochemotherapy Consolidation Chemotherapy in Preoperative Treatment of Rectal Cancer

The use of capecitabine based preoperative chemoradiation and adjuvant chemotherapy is standard treatment of locally advanced rectal cancer. It has reduced local recurrence rate to less than 10%, but has only had limited effect on overall survival due to the constantly high (more than 30%) rate of distant metastasis. Complete …

adenocarcinoma
chemoradiotherapy
adenocarcinoma of rectum
total mesorectal excision
capecitabine
  • 1 views
  • 08 Nov, 2020
  • 1 location
Radiotherapy With or Without Concurrent Chemotherapy for Extensive Lymphatic Metastasis of Esophageal Cancer - 3JECROG P-03

The investigators aimed to compare elective nodal irradiation versus involved field irradiation with or without concurrent chemotherapy and the addition of consolidation chemotherapy for

  • 20 views
  • 22 Jan, 2021
  • 1 location
Umbilical Cord Blood Transfusion in Consolidation Therapy of Elderly Patients With Acute Myeloid Leukemia

After complete remission, elderly AML patients cannot tolerate hematopoietic stem cell transplantation and standard-dose consolidation chemotherapy, and the 5-year survival rate is around 10

  • 0 views
  • 01 Sep, 2021
  • 2 locations
Concurrent Helical Tomotherapy With Chemotherapy in Unresectable Stage III Non-Small Cell Lung Cancer (NSCLC)

tomotherapy in 30 daily fractions over six weeks. Patients should have recovered fully from induction concurrent chemoradiotherapy before they continue with the consolidation chemotherapy phase

chemoradiotherapy
large cell carcinoma
measurable disease
kidney function test
docetaxel
  • 3 views
  • 07 Nov, 2020
  • 1 location
INFUSION OF ALLOREACTIVE NATURAL KILLER (NK) CELLS AS CONSOLIDATION STRATEGY FOR ACUTE MYELOID LEUKEMIA PATIENTS

Acute Myeloid Leukemia (AML) patients who had achieved Complete Remission (CR) after (re)induction/consolidation chemotherapy will receive the infusion of alloreactive NK cells. Adult AML

fludarabine
cyclophosphamide
cell transplantation
leukapheresis
immunosuppressants
  • 0 views
  • 03 Feb, 2021
  • 1 location
Midostaurin Associated With Standard Chemotherapy in Patients With Core-binding Factor Leukemia

The purpose of this single-arm, open label, phase-II trial, is to determine whether the association of Midostaurin to standard induction, consolidation therapy and in maintenance therapy as single agent, is effective in decrease relapse incidence, in patients with CBF-AML. The single-arm, open label, phase-II study is based on data obtained …

  • 0 views
  • 01 Feb, 2021
  • 2 locations