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Found 750 clinical trials
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OTIS Autoimmune Diseases in Pregnancy Project

The purpose of the OTIS Autoimmune Diseases in Pregnancy Study is to monitor planned and unplanned pregnancies exposed to certain medications, to evaluate the possible teratogenic effect of these medications and to follow live born infants for five years after birth. With respect to fetal outcome, it is important to …

teratogenic effect
autoimmune disease
  • 96 views
  • 11 Apr, 2021
  • 1 location
None
Early Biomarkers for ARthritic PAIN to Guide Improved Treatments for Arthritis

Osteoarthritis (OA) is a condition affecting the whole joint and is a major cause of pain and disability worldwide. Although OA is very common, the initial steps which lead to the development of pain and tissue damage are not fully understood. In this study participants will be investigated for markers …

osteoarthritis
psoriatic arthritis
anti-rheumatic drugs
steroidal anti-inflammatory drugs
DMARD
  • 493 views
  • 26 Jan, 2021
  • 1 location
None
Evolution and Treatments of Chronic Inflammatory Systemic Diseases

Patients with chronic inflammatory diseases (CID) followed in gastroenterology and rheumatology have physiopathological, epidemiological and therapeutic focal points. The pathologies concerned are inflammatory bowel diseases (IBD - Crohn's disease [MC] and ulcerative colitis [RCH]), and chronic inflammatory rheumatic diseases (rheumatoid arthritis [RA] and spondyloarthritis [SpA] including psoriatic arthritis [PsA]). Presenting …

psoriatic arthritis
colitis
spondylitis
ulceration
rheumatic diseases
  • 0 views
  • 23 Jan, 2021
  • 1 location
None
Low Dose Naltrexone to Improve Physical Health in Patients With Vasculitis

Naltrexone is an FDA approved drug (for alcoholism) that has found widespread use "off-label" to treat pain and improve quality of life at much lower doses than are used for the approved indication. There are a few scientific studies in three conditions (fibromyalgia, Crohn's disease, and multiple sclerosis) that suggest …

polyarteritis nodosa
anti-neutrophil cytoplasmic antibody
chest radiograph
intermittent claudication
livedo reticularis
  • 20 views
  • 28 Mar, 2021
  • 5 locations
None
Swiss Pediatric Inflammatory Brain Disease Registry (Swiss-Ped-IBrainD)

The Swiss-Ped-IBrainD is a national patient registry that collects information on diagnosis, symptoms, treatment, and follow-up of pediatric patients with an inflammatory brain disease in Switzerland. It was first implemented in 2020 in the pediatric clinic of the university hospital in Bern. Further centers all over Switzerland were opened for …

transverse myelitis
neuritis
multiple sclerosis
encephalitis autoimmune
encephalomyelitis
  • 0 views
  • 01 Sep, 2021
  • 12 locations
None
A Prospective Observational Study of the Real-world Use of an Adalimumab Biosimilar and Evaluation of Nutritional Status on the Therapeutic Response

The aim of the study is to describe the real-world profile of patients treated with adalimumab FK in gastroenterology, dermatology or rheumatology in order to evaluate in this population the predictive factors of therapeutic response (in particular nutritional status) and generate hypothesis between nutritional status and therapeutic response.

adalimumab
anti-tnf therapy
biosimilar
anti-tumor necrosis factor therapy
anti-tnf-alpha therapy
  • 0 views
  • 27 Sep, 2021
  • 1 location
None
VCRC Tissue Repository

The purpose of this study is to collect existing tissue specimens from subjects enrolled in Vasculitis Clinical Research Consortium (VCRC) studies. Analysis of these tissue specimens and linked clinical data collected through VCRC studies may lead to the identification and development of a series of translational research projects. Results of …

diagnostic tests
vascular diseases
vasculitis
vascular disease
  • 94 views
  • 02 Apr, 2021
  • 8 locations
None
One-Time DNA Study for Vasculitis

The purpose of this study is to identify genes that increase the risk of developing vasculitis, a group of severe diseases that feature inflammation of blood vessels. Results of these studies will provide vasculitis researchers with insight into the causes of these diseases and generate new ideas for diagnostic tests …

polyarteritis nodosa
anti-neutrophil cytoplasmic antibody
livedo reticularis
intermittent claudication
granulomatous inflammation
  • 122 views
  • 21 Apr, 2021
  • 14 locations
None
Studies of the Natural History Pathogenesis and Outcome of Idiopathic Systemic Vasculitis

Background Vasculitis is a group of diseases that inflame and damage blood vessels and tissue. It can cause many medical problems. Few tests can diagnose the disease, and none can reliably predict a relapse. Researchers want to study people s genes and follow people over time to see how the …

Accepts healthy volunteers
vasculitis
  • 25 views
  • 22 Oct, 2021
  • 1 location
None
Longitudinal Study of Neurodegenerative Disorders

The purpose of this study is to understand the course of rare genetic disorders that affect the brain. This data is being analyzed to gain a better understanding of the progression of the rare neurodegenerative disorders and the effects of interventions.

neurodegenerative disorders
cell transplantation
genetic disorder
palliative care
genetic disorders
  • 359 views
  • 13 Nov, 2021
  • 1 location