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Found 754 clinical trials
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Safety and Efficacy of Low-intensity Shockwave Therapy for Peyronie's Disease

Investigation of the effect of Low-intensity extracorporeal shockwave therapy (ESWT) for Peyronie's disease (PD) via a single blind, sham-controlled, randomized clinical trial. Investigators will not be blinded to group assignments, but penile curvature will be assessed from coded patient pictures by a blinded assessor.

  • 23 views
  • 02 May, 2021
  • 4 locations
None
Intermittent Pneumatic Compression in Women With Lipo-lymphedema (Lipedema With Swelling)

Lipedema is a connective tissue disorder that affects up to 10% of women. It is characterized by painful, swollen subcutaneous tissue and disproportionate fat accumulation (primarily in the

  • 54 views
  • 08 Apr, 2021
  • 1 location
None
The Effects of Prophylactic Limited Palmar Fasciectomy on Surgical Outcomes and Scarring

Research is instrumental for improving medical care and the patient experience. Finding new surgical techniques can create better outcomes and minimize recovery time and complications for patients. Some patients undergoing trigger finger surgery with a pre-existing Dupuytren's cord may develop a thickened surgical scar after surgery, which can cause discomfort, …

palmar fasciectomy
dupuytren's contracture
scarring
fasciotomy
discomfort
  • 841 views
  • 13 Jun, 2021
  • 1 location
None
Study of Anti-Malarials in Incomplete Lupus Erythematosus

This project is a multicenter, randomized, placebo-controlled, double-blind clinical trial that is designed to test whether treating patients who are at risk for development of lupus with hydroxychloroquine can slow accumulation of disease features. Effects on clinical progression of symptoms, patient-reported outcomes and changes in the immune markers of response …

lupus
hydroxychloroquine
antinuclear antibody
antimalarials
arthritis
  • 114 views
  • 09 Nov, 2021
  • 7 locations
None
Phase 2 Trial of Mesenchymal Stem Cells in Systemic Lupus Erythematosus (MiSLE)

The purpose of this study is to evaluate the efficacy and safety of mesenchymal stem cells (MSCs) obtained from umbilical cords for the treatment of adults with systemic lupus erythematosus (SLE). The goal of this study is to determine if patients receiving an MSC infusion plus standard of care respond …

cyclophosphamide
lupus
azathioprine
mycophenolate
nephritis
  • 170 views
  • 04 Oct, 2021
  • 9 locations
None
The Therapeutic Value and Mechanism of Recombinant Human Interleukin-2 on Children With Rheumatic Diseases

The study aims to explore the therapeutic value and mechanism of Interleukin-2 on children with rheumatic diseases (Systemic Lupus Erythematosus, Primary Sjgren Syndrome, Juvenile Idiopathic Arthritis).

lupus
sjogren's syndrome
rheumatic diseases
Accepts healthy volunteers
interleukin-2
  • 0 views
  • 22 Oct, 2021
  • 1 location
None
Telehealth CBT for Adolescents and Young Adults With Childhood-onset Systemic Lupus Erythematosus

This study aims to investigate the feasibility and effectiveness of a remotely delivered psychological intervention for youth with cSLE. This intervention aims to teach participants skills in order to cope with fatigue, pain, and depressive symptoms--symptoms that commonly affect adolescents and young adults with lupus.

lupus
  • 0 views
  • 18 Mar, 2021
  • 2 locations
None
O-GlcNAcylation Role in the Pathophysiology of Systemic Lupus Erythematosus

This study aims at defining the role of O-GlcNAcylation is in the physiopathology of systemic lupus erythematosus (SLE). O-GlcNAcylation is a metabolic pathway potentially implicated in SLE with potential for the discovery of new therapeutic strategies.

lupus
  • 2 views
  • 26 Jan, 2021
  • 1 location
None
A Study of ICP-022 in Patients With Systemic Lupus Erythematosus (SLE)

The purpose of the study is to assess the Safety, Tolerability, PK/PD and preliminary Efficacy of ICP-022 in Subjects with Systemic Lupus Erythematosus (SLE)

lupus
antinuclear antibody
  • 0 views
  • 31 May, 2021
  • 13 locations
None
Effect of Curcumin on Systemic Lupus Erythematosus

The purpose of this investigator initiated study is to determine the efficacy of curcumin on disease activity of subjects with systemic lupus erythematous. Curcumin has been found to have anti-inflammatory effects and has been found to improve disease activity in lupus patients. In addition, subjects with rheumatoid arthritis as well …

lupus
treatment regimen
arthritis
  • 3 views
  • 21 May, 2021
  • 1 location