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Found 1299 clinical trials
Reducing Right Ventricular Failure in Pulmonary Arterial Hypertension (RELIEVE-PAH)

The objectives of the RELIEVE-PAH study are to obtain first-in-human experience with the study device in patients with severe pulmonary arterial hypertension, including evidence of initial safety, device performance and possible signals of clinical effectiveness.

hypertension
connective tissue disease
right ventricular failure
  • 0 views
  • 27 Aug, 2021
  • 5 locations
Acute Effects of Exogenous Ketone Ester Administration in Heart Failure

The purpose of this study is to test whether a ketone ester drink will improve exercise in people with heart failure (HF) compared to a placebo. In HF, patients are limited in their ability to

  • 0 views
  • 06 May, 2022
  • 1 location
Acute Heart Failure With Reduced Ejection Fraction - COngestion Discharge Evaluation

The AHF-CODE reduced study is a prospective, non-randomized, monocenter study performed in patients with heart failure with reduced ejection fraction admitted for worsening heart failure.

  • 6 views
  • 30 Jan, 2021
  • 1 location
Acute Heart Failure With Preserved Ejection Fraction - COngestion Discharge Evaluation

The AHF-CODE preserved study is a prospective, non-randomized, monocenter study performed in patients with heart failure with preserved ejection fraction admitted for worsening heart failure

  • 12 views
  • 02 Feb, 2021
  • 1 location
Mechanisms of Exercise Intolerance in Heart Failure With Preserved Ejection Fraction

The global objective of this study is to determine the mechanisms of exercise intolerance and dyspnea on exertion (DOE) in patients with HFpEF and based on this pathophysiology, test whether specific exercise training programs (whole body vs single leg) will result in improved exercise tolerance.

diastolic dysfunction
ejection fraction
dyspnea
heart failure with preserved ejection fraction
  • 0 views
  • 27 May, 2022
  • 1 location
Mechanism and Effects of Manipulating Chloride Homeostasis in Stable Heart Failure

This study is designed to investigate the quantitative effects of sodium-free chloride supplementation on electrolyte balance, volume status, and sodium avidity in stable heart failure patients

  • 1 views
  • 26 May, 2022
  • 1 location
Splanchnic Nerve Block for Therapy of Chronic Heart Failure (Splanchnic III)

Splanchnic vasoconstriction may contribute to decompensation of chronic heart failure (HF) via volume redistribution from the splanchnic vascular bed to the central compartment. This is a

  • 0 views
  • 30 Nov, 2021
  • 1 location
Evaluation of Blood Volume Analysis- Guided Management of Decompensated Heart Failure

Diuretic therapy is first-line treatment for acute decompensated heart failure. However, accurate assessment and management of patient blood volume is challenged by the limitations of physical

  • 0 views
  • 09 Aug, 2022
  • 1 location
Prevention of Heart Failure Induced by Doxorubicin With Early Administration of Dexrazoxane (PHOENIX1)

The purpose of this research study is to determine whether early administration of Dexrazoxane prevents Doxorubicin induced cardiotoxicity.

Accepts healthy volunteers
  • 0 views
  • 27 Apr, 2022
  • 1 location
Cardiovascular Effects of Preferred Home-based Exercise Training in Systolic Heart Failure

that that may be implemented into novel intervention tools aiming to increase exercise adherence in patients with chronic heart failure.

ejection fraction
systolic heart failure
medical therapy
  • 0 views
  • 08 Oct, 2021
  • 1 location