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Found 1321 clinical trials
Advanced Cardiac Imaging in Cardiac Allograft Vasculopathy

Cardiac allograft vasculopathy (CAV) is a process of both immune and non-immune mediated thickening of the heart arteries of transplanted hearts. CAV limits the long term survival of heart transplant patients and is one of the common causes of death in the late post transplant period. Current methods of detecting …

intravascular ultrasound
computed tomography
  • 21 Jan, 2021
  • 1 location
Non Invasive Use of Pressure-Volume Loop in the Operating Room

In patients under general anesthesia, the prevention of intraoperative hypotension to maintain blood pressure (BP) close to the initial blood pressure, i.e. before anesthesia, is essential to reduce the risk of death and improve surgical outcomes. Vasoactive agents are commonly used to correct this hypotension (Phenylephrine Ephedrine Noradrenaline). These three …

  • 11 Mar, 2021
  • 1 location
Muscle Weakness in COVID-19 Patients (MIOCOVID)

Although the Covid-19 infection mainly manifests itself with respiratory symptoms, as early as two months after the onset of the pandemic, the presence of other symptoms, including muscle ones, became clear. With the disappearance of the emergency and the advancement of knowledge, medium- and long-term effects have been reported at …

  • 27 May, 2022
  • 1 location
Determinants of the Progression and Outcome of Mitral Regurgitation

Mitral regurgitation (MR) is one of the most frequent valve lesions, both in North America and in Europe, and its prevalence is increasing with the aging of the population. Organic Mitral Regurgitation (OMR) and Ischemic Mitral Regurgitation are the 2 main categories of MR. Organic or primary MR is caused …

ischaemic mitral regurgitation
cardiopulmonary exercise testing
  • 05 Nov, 2021
  • 5 locations
MACCE in Hospitalized Patients With Community-acquired Pneumonia

Community-acquired pneumonia is the most common infection leading to hospitalization in intensive care units and the most common cause of death associated with infection disease. Epidemiological studies have shown that respiratory tract infections are associated with an increased risk for the development of acute cardiovascular and cerebrovascular events. This link …

platelet aggregation
respiratory infection
  • 06 Oct, 2021
  • 1 location
Inflammatory Pathways and Cardiac Growth Factors Associated With Fabry Disease Cardiomyopathy

In Fabry disease (FD), -galactosidase A deficiency leads to the accumulation of globotriaosylceramide (Lyso-Gb3 and Gb3), triggering a pathologic cascade that causes progressive damage to multiple organs, including the heart. The heart is one of the organs that is very sensitive to the deficiency of -galactosidase A. There is a …

  • 05 Feb, 2021
  • 1 location
Early Detection of Cardiotoxicity From Systemic and Radiation Therapy in Breast Cancer Patients

To assess the role of myocardial oedema on CMR (T2 mapping) after radiation therapy and cardiotoxic systemic therapy in predicting the incidence of cardiotoxicity, defined as by consensus guidelines* (decline of LVEF 10% points with a final LVEF <53%) measured on CMR and ECHO over the time window of 12 …

  • 17 Mar, 2021
  • 1 location
Evaluation of Relationship Between Preoperative Fibrinogen/Albumin Ratio and Morbidity After Hip Fracture Operations

Due to the aging of populations, hip fracture operations are increasing from year to year. This operations have many complications also high morbidity and the mortality. Population of this study is oldest old age patients who will have an operation because of hip fracture. The primary outcome of this study …

  • 22 Apr, 2022
  • 1 location
Impact of Hypoxia on Resting and Exertional Right Ventricular Performance

The purpose of this study is to better understand how hypoxia (low oxygen) affects resting and exertional right ventricular function in healthy individuals.

Accepts healthy volunteers
  • 19 Apr, 2022
  • 1 location
The CoAGulation Biomarkers and Atrial Fibrillation (COAG-AF) Pilot Study

The aim of the Correlation Of CoAGulation-Atrial Fibrillation (COAG-AF) study is to prove that an increase in pro-thrombotic biomarkers in AF is associated with an increase in AF burden. Secondary objectives of the study are the following: To investigate the impact of catheter ablation on serum pro-thrombotic biomarkers in patients …

catheter ablation
  • 13 Oct, 2021
  • 1 location