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Found 496 clinical trials
Omalizumab Before Onset of Exacerbations (OBOE)

points, within 72 hours of onset of a URI as defined by onset of (or substantial worsening of) rhinorrhea, nasal congestion or sneezing (single or multiple symptoms) and 3-6 days after study drug

  • 0 views
  • 22 Sep, 2022
  • 1 location
Comparison of the Effects for Lightening the Shiners Among Different Treatments for Rhinitis

or non-allergic rhinitis, shiners are believed to be caused by venous stasis resulting from nasal congestion. This study is aiming that comparison of the effectiveness of treatment of rhinitis

  • 0 views
  • 13 May, 2022
  • 1 location
Breathing Exercise Against Dyspnoea in Heart Failure Patients to Improve Chemosensitivity (Breathe-HF)

left ventricular ejection fraction (HFrEF, HFpEF). Severity of this exaggerated response is associated with poor prognosis. This response may be triggered by pulmonary congestion and peripheral muscle

ejection fraction
dyspnea
medical therapy
congestion
heart failure
  • 0 views
  • 18 Apr, 2022
VExUS-guided Fluid Management in Patients With Acute Kidney Injury in the Intensive Care Unit (AKIVEX)

A quasi experimental study that aims to verify whether the incorporation of VExUS in patients with AKI in the Intensive Care Unit (ICU) may prompt tailored interventions to increases the number of days free from Renal Replacement Therapy (RRT) during the first 28 days.

renal replacement therapy
  • 0 views
  • 22 Mar, 2022
  • 1 location
Protocolized Diuretic Therapy Compared to Standard Care in Emergency Department Patients With Acute Heart Failure

This is a randomized trial of protocolized diuretic therapy guided by urinary sodium compared to structured usual care in ED patients with AHF. Participants will be recruited following an initial standard evaluation in the ED and randomized in a 1:1 fashion to structured usual care or protocolized diuretic therapy guided …

edema
heart failure
diuretic therapy
acute heart failure
  • 0 views
  • 04 Jun, 2022
  • 1 location
An Evaluation of the Safety and Performance of the Aortix System for Intra-Aortic Mechanical Circulatory Support in Patients With Cardiorenal Syndrome

The Aortix CRS Pilot Study: An Evaluation of the Safety and Performance of the Aortix System for Intra-Aortic Mechanical Circulatory Support in Patients with Cardiorenal Syndrome

dyspnea
diuretics
congestion
heart failure
edema
  • 35 views
  • 15 Sep, 2022
  • 14 locations
Erenumab for Idiosyncratic Facial Pain

This is a phase IV randomized, double-blinded, placebo-controlled study to evaluate the efficacy of Erenumab in subjects with midfacial pain or pressure, without clinical or radiographic evidence of sinusitis.

edema
  • 0 views
  • 10 Jul, 2022
  • 1 location
Semi-sitting Versus Supine Position in Endoscopic Skull Base Surgery (PosESS)

This study is to prospectively compare the standard supine (control group) and the semi-sitting position (head elevation of 30°; intervention group) in endoscopic endonasal pituitary surgery.

  • 0 views
  • 20 Apr, 2022
  • 1 location
Efficacy and Safety of Dapagliflozin in Acute Heart Failure (DICTATE-AHF)

This is a randomized trial of the addition of dapagliflozin to patients with or without type 2 diabetes hospitalized with acute decompensated heart failure (ADHF). Participants will be recruited following an initial standard evaluation in the ED and randomized within 24 hours of presentation for ADHF in a 1:1 fashion …

hemoglobin a1c
dapagliflozin
dyspnea
diuretics
congestion
  • 58 views
  • 21 Mar, 2022
  • 6 locations
Implantation of a Permanent Interatrial Shunt to Reduce Left Atrial Filling Pressures Following MitraClip

This is an investigator initiated, prospective study to demonstrate the safety and feasibility of implantation of the V-Wave Interatrial Shunt System (herein called the "V-Wave Shunt" in patients immediately following percutaneous mitral valve repair using the MitraClip system.

  • 0 views
  • 24 Apr, 2022
  • 1 location