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Found 541 clinical trials
Evaluation of Post-operative Nurse-based Heart Failure Care in Non-cardiac Surgery

Patients with heart failure NYHA >= II receiving non-emergent non-cardiac in-patient surgery will be randomized to receive either standard post-operative care (surgeon has to ask actively for specialist cardiological support) or a nurse-based heart failure management (nurses provide week-day support every day after surgery, if needed together with a heart …

  • 24 Jan, 2021
  • 2 locations
Therapeutic Education Strategy for Patients With Acute Heart Failure

The EduStra-HF study will examine the impact of an intensive therapeutic education on patients discharged from hospital after an episode of acute heart failure (HF). Patients will be randomized into two groups: one will receive "usual care" monitoring and one will receive a specific educational monitoring programme for 1 year. …

acute heart failure
  • 19 Mar, 2021
  • 7 locations
Efficacy and Safety of Sacubitril/Valsartan Compared With Enalapril on Morbidity Mortality and NT-proBNP Change in Patients With CCC

The purpose of this study is to evaluate the effect of sacubitril/valsartan 200 mg BID compared with enalapril 10 mg BID, in addition to conventional heart failure (HF) treatment, in improving a hierarchical composite of cardiovascular (CV) events (i.e. CV death or the occurrence of first HF hospitalization) and causing …

serology test
ventricular angiography
ejection fraction
  • 09 Apr, 2021
  • 5 locations
GOREISAN for Heart Failure (GOREISAN-HF) Trial

The objective of the GOREISAN-HF trial is to assess the effect of the administration of Goreisan (TJ-17) plus standard therapy compared to standard therapy alone on the improvement rate of cardiac edema and clinical outcomes in worsening congestive heart failure with volume overload.

  • 19 Feb, 2021
  • 1 location
Care Coordination to Assess Improvement in Outcomes in Hospital Readmissions

Heart failure is a syndrome that is defined by distinctive clinical, hemodynamic, and neurohormonal findings. HF represents a final common pathway for many different cardiovascular diseases, including coronary disease, hypertension, Valvular disease, and many primary heart muscle diseases. Clinically, HF patients experience dyspnea, fatigue and diminished exercise tolerance, reflecting elevated …

coronary disease
b-type natriuretic peptide
medical therapy
  • 23 Jun, 2021
  • 1 location
Mobile Integrated Health in Heart Failure

The purpose of this study is to compare how two different types of care after a hospitalization reduce hospital readmissions and symptom burden. The two types of care are a Transitions of Care Coordinator and Mobile Integrated Health. In the Transitions of Care Coordinator group, participants will receive a phone …

heart failure
  • 30 May, 2021
  • 2 locations
Comparison of CRT-D and CRT-DX Systems (CRT-NEXT)

The principal objective is to test non-inferiority of the CRT-DX system as compared to a conventional CRT-D system, in terms of the combined endpoint of mortality, hospitalizations due cardiovascular causes, any complication leading to loss of lead functionality, in the subset of patients without evidence of sinus dysfunction on optimal …

  • 22 Jan, 2021
  • 14 locations
Electronic Alerts for Heart Failure Prevention in Diabetes

Type 2 diabetes mellitus (T2DM) is an independent risk factor for heart failure (HF) and is associated with significant morbidity and mortality. Recent therapeutic advances in pharmacotherapies, such as sodium-glucose cotransporter-2 inhibitors (SGLT2i), have shown to be beneficial in preventing HF among patients with T2DM. However, despite widely available risk …

  • 07 May, 2021
  • 1 location
Cryoballoon Ablation Versus Medical Therapy in Patients With Heart Failure and Atrial Fibrillation

Rationale Atrial fibrillation (AF) and heart failure (HF) can cause each other and sustain each other. Combined, the two diseases negatively influence each other's prognosis and lead to higher mortality. Studies in HF patients in which the AF burden is reduced by AF ablation show promising results toward improved prognosis, …

  • 24 Mar, 2021
  • 2 locations
DANISH-CRT - Does Electric Targeted LV Lead Positioning Improve Outcome in Patients With Heart Failure and Prolonged QRS

Heart failure is a leading cause of morbidity and mortality. Cardiac resynchronization therapy (CRT) is a well-established treatment for patients with symptomatic heart failure in spite of optimised medical treatment (OMT), reduced left ventricular pump function with left ventricular ejection fraction (LVEF) 35% and prolonged activation of the ventricles (bundle …

ejection fraction
heart disease
cardiac resynchronization therapy
  • 23 Jan, 2021
  • 5 locations