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Found 540 clinical trials
How is COGNItive Function Affected by Cardiac Resynchronisation Therapy?

The primary objective of COGNI-CRT is to assess whether Cardiac Resynchronisation Therapy (CRT) can improve cognitive function in patients with systolic HF (LVEF 35%), when compared to a control group of patients implanted with an Implantable Cardioverter-Defibrillator (ICD) or a permanent pacemaker (PPM) with systolic HF (LVEF 35%). This clinical …

nt-probnp
heart failure
b-type natriuretic peptide
depression
cardiac resynchronization therapy
  • 0 views
  • 25 Jan, 2021
  • 1 location
BAROSTIM THERAPY in Heart Failure With Reduced Ejection Fraction

The purpose of this registry (NCT02880618) is to evaluate the effect of BAROSTIM THERAPY with the BAROSTIM NEO System in the commercial setting in subjects recently implanted under the CE-Marked indication for heart failure with reduced ejection fraction (HFrEF).

heart failure
ejection fraction
  • 34 views
  • 25 Jan, 2021
  • 49 locations
Speckle Tracking Imaging and Realtime 3 Dimensional Echocardiograhy to Study LV Function and Remodeling After Acute Myocardial Infarction (AMI)

Left ventricular (LV) remodeling after acute myocardial infarction (AMI) has been well described in previous studies. However, there is a paucity of data on the incidence of and risk factors for LV remodeling in modern clinical practice that incorporates widespread use of acute reperfusion strategies and almost systematic use of …

infarct
angiotensin
heart failure
angiotensin converting enzyme
ace inhibitor
  • 17 views
  • 07 Nov, 2020
Implantable Cardioverter Defibrillators And Magnetic Resonance Imaging of the Heart at 1.5 Tesla

To evaluate short-term and long-term effects by MR imaging on the technical and functional status of implantable cardioverter defibrillators.

implantable cardioverter-defibrillators
cardiac mri
congestive heart failure
  • 8 views
  • 07 Nov, 2020
  • 1 location
Recovery From ICUAW Following Severe Respiratory and Cardiac Failure

To observe and identify determinants of recovery from intensive care unit-acquired weakness (ICUAW) following a severe cardiorespiratory failure requiring extra-corporeal membrane oxygenation (ECMO). Additionally, to discover the effects of ICUAW on physical function and health-related quality of life (HRQoL) after critical illness. CLEVERER is a clinical observational pilot study.

critical illness
heart failure
weakness
respiratory failure
cardiorespiratory failure
  • 10 views
  • 27 Jan, 2021
  • 1 location
Management of Depression and Anxiety in HF

Heart failure (HF) is a complex clinical syndrome characterized by inability of the heart to pump an adequate amount of blood. Heart failure affects patients' ability to carry out even simple activities of daily living and therefore has negative psychological impact. Many studies reported that depression is prevalent among HF …

  • 0 views
  • 26 Jan, 2021
  • 1 location
Sleep Apnea Coronary Atherosclerosis and Heart Failure in Diabetes Patients With Nephropathy

Background Diabetes, and especially diabetic kidney disease is associated with the development of cardiovascular disease such as calcification in the coronary arteries and heart failure. Sleep apnea is frequent among patients with diabetes and diabetic kidney disease and sleep apnea itself is a solitary risk factor in the development of …

stiffness
heart failure
obstructive sleep apnea
atherosclerosis
cardiovascular complications
  • 5 views
  • 26 Jan, 2021
  • 1 location
Optimising Secondary Prevention and Quality of Life in Early Cardiac Rehabilitation

The primary aim of this research is to explore the adherence and drop-out from early cardiac rehabilitation (CR), to inform interventions to support patient's adherence to CR and facilitate maintenance. The secondary aim is to understand which aspects of CR are essential for improving health-related quality of life in the …

bypass graft
infarct
heart failure
rehabilitation program
cardiac rehabilitation
  • 0 views
  • 19 Jun, 2021
  • 6 locations
Whole Exome Sequencing in Finding Causative Variants in Germline DNA Samples From Patients With Congestive Heart Failure Receiving Therapy for Breast Cancer

This research trial studies whole exome sequencing in finding causative variants in germline deoxyribonucleic acid (DNA) samples from patients with congestive heart failure receiving therapy for breast cancer. Studying samples of germline DNA in the laboratory from patients with congestive heart failure receiving therapy for breast cancer may help doctors …

anthracycline
breast cancer
anthracyclines
bevacizumab
cancer
  • 23 views
  • 29 Mar, 2021
  • 1 location
Evaluating Right Ventricular (RV) Size and Function Using the Upper Valley RV Algorithm and Novel Imaging Modalities

The primary purpose of this study is to evaluate the diagnostic performance of three methods for measuring right ventricular size and function including the Philips Novel RV quantification technologies (RV Heart Model volumetric analysis and Philips 2D strain) and the Upper Valley Right Ventricle Algorithm (UVRV) algorithm as compared to …

strain
diagnostic procedures
MRI
cardiac mri
  • 8 views
  • 26 Jan, 2021
  • 1 location