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Found 520 clinical trials
Dapagliflozin and Effect on Cardiovascular Events in Acute Heart Failure -Thrombolysis in Myocardial Infarction 68 (DAPA ACT HF-TIMI 68)

This is an international, multicenter, parallel-group, randomized, double-blind, placebo-controlled trial in patients who have been stabilized during hospitalization for acute heart failure, evaluating the effect of in-hospital initiation of dapagliflozin versus placebo on the clinical outcome of cardiovascular death or worsening heart failure.

angiotensin
inotropes
pro-brain natriuretic peptide
diagnostic tests
fluid overload
  • 0 views
  • 26 Dec, 2021
GOREISAN for Heart Failure (GOREISAN-HF) Trial (GOREISAN-HF)

The objective of the GOREISAN-HF trial is to assess the effect of the administration of Goreisan (TJ-17) plus standard therapy compared to standard therapy alone on the improvement rate of cardiac edema and clinical outcomes in worsening congestive heart failure with volume overload.

congestive heart failure
fluid overload
b-type natriuretic peptide
diuretics
pulmonary congestion
  • 2 views
  • 27 Apr, 2022
  • 1 location
Electronic Alerts for Heart Failure Prevention in Diabetes

Type 2 diabetes mellitus (T2DM) is an independent risk factor for heart failure (HF) and is associated with significant morbidity and mortality. Recent therapeutic advances in pharmacotherapies, such as sodium-glucose cotransporter-2 inhibitors (SGLT2i), have shown to be beneficial in preventing HF among patients with T2DM. However, despite widely available risk …

type 2 diabetes mellitus
diabetes
heart failure
  • 0 views
  • 28 Apr, 2022
  • 1 location
Intravenous Thyroxine for Heart-Eligible Organ Donors

This randomized controlled trial will evaluate whether intravenous thyroxine infusion given to brain-dead organ donors who are eligible to donate hearts for 12 hours will result in more hearts transplanted than saline placebo

inotropic agent
  • 0 views
  • 08 Dec, 2021
  • 14 locations
Improving Antibiotic Use in Urgent Care Facilities (SCORE_UC)

This study will implement a comprehensive outpatient stewardship program targeting a large network of Urgent Care (UC) clinics within Intermountain Helathcare.

Accepts healthy volunteers
  • 0 views
  • 19 Apr, 2022
  • 1 location
DANISH-CRT - Does Electric Targeted LV Lead Positioning Improve Outcome in Patients With Heart Failure and Prolonged QRS

Heart failure is a leading cause of morbidity and mortality. Cardiac resynchronization therapy (CRT) is a well-established treatment for patients with symptomatic heart failure in spite of optimised medical treatment (OMT), reduced left ventricular pump function with left ventricular ejection fraction (LVEF) 35% and prolonged activation of the ventricles (bundle …

heart disease
heart failure
cardiac resynchronization therapy
ejection fraction
crt-p
  • 0 views
  • 04 Mar, 2022
  • 4 locations
Assessment of the Axone Micro Quadripolar Lead for Enhanced Cardiac Resynchronization Therapy

The primary objective of this study is to assess the chronic safety and performance of the Axone left ventricular (LV) micro-lead.

cardiac resynchronization therapy
  • 0 views
  • 18 Dec, 2021
  • 14 locations
Transitional Care Model Evaluation 2020

The study is a randomized controlled trial to estimate the effects of the transitional care model (TCM) on hospital admissions and patients' experience during the year following the patient's qualifying discharge. The University of Pennsylvania, where TCM was developed, will be the coordinating center for the implementation. The study will …

chronic obstructive pulmonary disease
heart failure
COPD
pneumonia
copd exacerbation
  • 0 views
  • 25 Jan, 2021
  • 1 location
Enhancing Community Health Through Patient Navigation, Advocacy and Social Support (ENCOMPASS)

Some patients who have multiple long-term health conditions have significant challenges accessing needed services despite available primary care and social services resources. Patient navigation programs may help those with complex health conditions improve their care and outcomes and if delivered by community health navigators (CHNs) who have close community ties, …

pulmonary disease
chronic disease
congestive heart failure
COPD
hypertension
  • 166 views
  • 03 Jun, 2022
  • 1 location
ANTHEM-HFrEF Pivotal Study

A multi-center randomized controlled clinical trial to evaluate Autonomic Regulation Therapy with the VITARIA system in patients with symptomatic heart failure and reduced ejection fraction.

medical therapy
diuretics
b-type natriuretic peptide
n-terminal pro-bnp
nt-probnp
  • 186 views
  • 15 Jun, 2022
  • 22 locations