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Found 540 clinical trials
A Comparison of Hydrochlorothiazide and Metolazone in Combination With Furosemide in Congestive Heart Failure Patients

The purpose of this research study is to compare the effectiveness of hydrochlorothiazide or metolazone in combination with furosemide. Patients with heart failure suffer from swelling because of too much fluid in the body. Furosemide, hydrochlorothiazide, and metolazone are all water pills used to treat the swelling. For most patients, …

congestive heart failure
edema
beta-adrenergic blocking agents
furosemide
ejection fraction
  • 8 views
  • 07 Nov, 2020
  • 1 location
Congestive Heart Failure Surgical Treatmment With Autologous Stem Cell Therapy

This research study was designed to test the safety and effectiveness of autologous stem cell graft in the myocardium of patients with refractory Congestive Heart Failure (CHF) with ischemic etiology. Cellular implantation will take place during off-pump revascularization surgery or during an ad hoc procedure using a mini-thoracotomy access.

congestive heart failure
  • 7 views
  • 07 Nov, 2020
  • 1 location
Reversible Pulmonary Artery Banding as Simplified Management of End-stage Dilated Left Ventriculopathy in Early Life

The purpose of this study is to: 1) Remodel and restore left ventricular geometry and function. 2) Avoid the need for mechanical circulatory support (MCS) and/or cardiac transplantation (CT). 3) Confirm the outcomes of a pilot study completed in Germany and reported in The Journal of Heart and Lung Transplantation …

  • 5 views
  • 26 Feb, 2021
  • 1 location
ACPs Combined With CABG in Patients With CHF

Study title: A Study of Combined Coronary Artery Bypass Grafting (CABG) and Blood-Borne Autologous Angiogenic Cell Precursors Therapy in Patients with Congestive Heart Failure due to Ischemic Heart Disease (ACPs-CHF) Principle Investigator: Kit V. Arom ,M.D.,Ph.D. Deputy Director, Chief Cardio-Thoracic Surgeon, Bangkok Heart Hospital Study objective : To determine the …

heart disease
congestive heart failure
  • 7 views
  • 07 Nov, 2020
  • 1 location
Skeletal Muscle Dysfunction in Heart Failure

Patients suffering from congestive heart failure report reduced exercise capacity. This skeletal muscle dysfunction is also detectable when using small muscle groups which should not put any demand on the heart. We hypothesize that congestive heart failure has systemic effects that causes the skeletal muscle dysfunction.

ejection fraction
congestive heart failure
  • 5 views
  • 07 Nov, 2020
  • 2 locations
Penile Transplant Study

One case of unsuccessful penile transplantation has been reported from China. The patient had suffered an industrial machine accident and lost his penis to the level of the pubic skin. Unfortunately the patient's wife insisted at about two weeks post-operatively that the organ be removed. At the time of surgical …

  • 397 views
  • 22 Jan, 2021
  • 1 location
PREVENT-HF: Prevention of Heart Failure Events With Impedance Cardiography Testing

The purpose of this study is to determine whether outpatient therapeutic management guided by impedance cardiography (ICG), in addition to standard clinical assessment, will result in a longer time in days to the first heart failure hospitalization than therapy guided by clinical assessment alone.

chronic heart failure
  • 26 views
  • 07 Nov, 2020
  • 3 locations
Reducing Lung CongestIon Symptoms in Advanced Heart Failure

The objective of the RELIEVE-HF study is to provide reasonable assurance of safety and effectiveness of the V-Wave Interatrial Shunt System by improving meaningful clinical outcomes in patients with New York Heart Association (NYHA) functional Class II, Class III, or ambulatory Class IV heart failure (HF), irrespective of left ventricular …

heart failure with preserved ejection fraction
ejection fraction
heart failure
b-type natriuretic peptide
pulmonary congestion
  • 48 views
  • 13 Jun, 2021
  • 130 locations
Pediatric Bronchiolitis Quality Improvement

of viral respiratory illness, such as sneezing, nasal congestion, and cough. Often, hospitalization is required for respiratory distress and to support hydration needs. Evidence based

treatment guidelines
antibacterial
oximetry
chest physiotherapy
sneezing
  • 2 views
  • 26 Apr, 2021
  • 1 location
Study Evaluating the Efficacy and Safety of Intranasal Administration of OPN-375 in Subjects With Chronic Sinusitis With or Without the Presence of Nasal Polyps

This is a 24-week randomized, double-blind, placebo-controlled, parallel-group, multicenter study to evaluate the efficacy and safety of intranasal administration of 186 and 372 g twice daily (BID) of OPN-375 in subjects with chronic sinusitis (CS) with or without nasal polyps.

rhinorrhea
facial pain
nasal congestion
nasal polyp
edema
  • 338 views
  • 20 Jun, 2021
  • 93 locations