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Found 427 clinical trials
Dapagliflozin on Volume Vascular Outcomes. (DAPA-VOLVO)

The purpose of the DAPA-VOLVO trial is to investigate the effects of Dapagliflozin on top of recommended standard therapy on volume status and vascular function in clinically stable de novo or chronic heart failure patients after hospitalization because of an acute decompensated heart failure event.

decompensated heart failure
acute decompensated heart failure
chronic heart failure
  • 0 views
  • 04 Oct, 2022
  • 1 location
Noninvasive Diagnostics in Left Ventricular Assist Device Patients

Study Purpose: The purpose of this study is to evaluate the sensitivity/specificity of noninvasive diagnostic methods for the cardiac function that are based on data available from the Left Ventricular Assist Device (LVAD). These diagnostic methods will be compared to standard clinical diagnostic procedures both at rest and during exercise. …

heart failure
  • 68 views
  • 26 Sep, 2021
  • 1 location
Treating Congestive Heart Failure Patients With Human iPSC-derived Cardiomyocytes Through Catheter-based Endocardial Injection

Heart failure is the primary cause of morbidity and mortality worldwide. Currently drug treatments for heart failure manage the symptoms, but not restore the loss cardiomyocytes due to the very limited regenerative capability in the adult heart. Novel reparative therapies that replace the cardiomyocytes loss are highly demanded to restore …

heart failure
ejection fraction
congestive heart failure
infarct
myocardial infarction
  • 0 views
  • 16 Oct, 2022
  • 1 location
Direct HIS/LBB Pacing as an Alternative to Biventricular Pacing in Patients With HFrEF and a Typical LBBB.

The study will investigate the feasibility of using direct HIS pacing or left bundle branch pacing (LBB pacing) as an alternative to biventricular pacing in patients with symptomatic heart failure and an ECG with a typical left bundle branch block pattern.

heart failure
atrio-biventricular pacing
left bundle branch block
crt-p
cardiomyopathy
  • 0 views
  • 15 Aug, 2021
  • 1 location
Catheter Ablation for Atrial Fibrillation in patientS With End-sTage Heart Failure and Eligibility for Heart Transplantation

CASTLE-HTx will determine if AF ablation has beneficial effects on mortality in patients with end stage HF who are eligible for HTx

fibrillation
heart failure
primary prevention
ejection fraction
catheter ablation
  • 0 views
  • 28 Sep, 2021
  • 1 location
The Cardiac Effects of Empagliflozin in Patients With High Risk of Heart Failure

The aim of this trial is to assess the effect of Empagliflozin on cardiac mass, volumes, cardiac biomarkers, metabolism, daily activity level, health-related quality of life in patients in elderly and obese patients with increased risk of developing heart failure. The primary hypotheses are that 180 days of treatment with …

heart failure
hypertension
ischemia
body mass index
stroke
  • 0 views
  • 25 Oct, 2021
  • 2 locations
Cohort of Heart Failure Patients (LOOP-HF)

This is a prospective cohort study of patients with Heart Failure with an eighteen-month follow-up aimed to collect all demographic, clinical, biological and para-clinical data to study population characteristics, assess prognosis markers and occurrence of HF treatment side effects. Congestive Heart failure is a frequent pathology and its prevalence increases …

b-type natriuretic peptide
beta-adrenergic blocking agents
congestive heart failure
angiotensin
cardiac resynchronization therapy
  • 22 views
  • 26 Feb, 2022
Selective Cytopheretic Device (SCD) Trial

The purpose of this study is to evaluate the selective cytopheretic device on the immune dysregulated state of congestive heart failure(CHF) with CRS and to assess the benefit of the device to improve cardiovascular and renal function. The study will enroll eligible patients in the ICU with acute on chronic …

loop diuretic
congestive heart failure
angiotensin
systolic heart failure
valsartan
  • 0 views
  • 20 Feb, 2022
  • 1 location
Peri-treatment of SGLT-2 Inhibitor on Myocardial Infarct Size and Remodeling Index in Patients With Acute Myocardial Infarction and High Risk of Heart Failure Undergoing Percutaneous Coronary Intervention

We aimed to identify whether SGLT-2 inhibitor administration before and after coronary intervention is effective in reducing the size of infarction and myocardial remodeling in patients with acute myocardial infarction (AMI) and high risk of heart failure, and its mechanism. For this reason, we compared cardiac magnetic resonance imaging (CMR) …

MRI
pulmonary congestion
heart failure
troponin
ejection fraction
  • 0 views
  • 22 Aug, 2021
  • 1 location
Leveraging Home Health Aides to Improve Outcomes in Heart Failure

The purpose of the study is to determine the effectiveness of an intervention among home health aides caring for adults admitted to home care with a primary diagnosis of heart failure at Visiting Nurse Service of New York's (VNSNY) Partners in Care (home care agency). The study will examine the …

heart failure
  • 0 views
  • 08 Jul, 2022
  • 1 location