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Found 34 clinical trials
A Multi-center Randomized Controlled Trial of Efficacy and Safety of Intravenous Ketamine for Chronic Daily Headaches: The KetHead Study (KetHead)

Chronic daily headaches (CDH) poses a significant burden on patients, healthcare systems and the society. Intravenous (IV) ketamine infusion, an intervention that is widely available and

  • 0 views
  • 22 Oct, 2022
  • 1 location
Physiological-based Cord Clamping in Congenital Diaphragmatic Hernia (PinC)

Pulmonary hypertension is a major determinant of postnatal survival in infants with a congenital diaphragmatic hernia (CDH). The current care during the perinatal stabilisation period in infants

congenital diaphragmatic hernia
hypertension
umbilical cord clamping
diaphragmatic hernia
pulmonary hypoplasia
  • 0 views
  • 12 Jul, 2022
  • 5 locations
Milrinone in Congenital Diaphragmatic Hernia

Infants with congenital diaphragmatic hernia (CDH) usually have pulmonary hypoplasia and persistent pulmonary hypertension of the newborn (PPHN) leading to hypoxemic respiratory failure (HRF

mechanical ventilation
arterial blood gas
nitric oxide
pco2
right ventricular overload
  • 73 views
  • 03 Nov, 2021
  • 16 locations
Fetal Endoscopic Tracheal Occlusion (FETO) Trial for Congenital Diaphragmatic Hernia (CDH) (FETO)

This is a single site pilot trial to assess the feasibility and safety of treating severe CDH with Fetal Endoscopic Tracheal Occlusion with the Goldballoon Detachable Balloon (GOLDBAL2) along

diaphragmatic hernia
pulmonary hypoplasia
  • 0 views
  • 28 Feb, 2022
  • 1 location
Smart Removal for Congenital Diaphragmatic Hernia

with congenital diaphragmatic hernia and moderate to severe pulmonary hypoplasia.

  • 0 views
  • 07 Nov, 2021
  • 1 location
A Trial of Phosphodiesterase-5 Inhibitor in Neonatal Congenital Diaphragmatic Hernia (TOP-CDH)

Congenital diaphragmatic hernia (CDH) occurs in approximately 1 in 3000 US live births, similar to the incidence seen within the Utah Birth Defects cohort. The diaphragmatic defect compromises

sildenafil
nitric oxide
phosphodiesterase-5 (pde-5) inhibitor
congenital diaphragmatic hernia
  • 0 views
  • 21 Oct, 2022
  • 1 location
Pilot Trial of Fetoscopic Endoluminal Tracheal Occlusion (FETO) in Severe Left Congenital Diaphragmatic Hernia (CDH)

ventilator-induced lung injury, morbidity and mortality rates for babies with severe CDH remain high. The rationale for fetal therapy in severe CDH is to promote adequate lung growth for neonatal survival

Accepts healthy volunteers
  • 0 views
  • 16 May, 2022
  • 1 location
Umbilical Cord Blood Mononuclear Cells for Hypoxic Neurologic Injury in Infants With Congenital Diaphragmatic Hernia (CDH)

diaphragmatic hernia (CDH).

arterial blood gas
diaphragmatic hernia
mononuclear cells
  • 21 views
  • 18 Apr, 2022
  • 1 location
Pilot Trial of Fetoscopic Endoluminal Tracheal Occlusion (FETO) in Fetuses With Severe Congenital Diaphragmatic Hernia (CDH) (FETO)

This is a single site pilot trial to study the feasibility of Fetoscopic Endoluminal Tracheal Occlusion (FETO) therapy in the most severe group of fetuses with congenital diaphragmatic hernia

  • 0 views
  • 16 Oct, 2022
  • 1 location
Study of Fetoscopic Endoluminal Tracheal Occlusion (FETO) in Fetuses With Severe Left Congenital Diaphragmatic Hernia (CDH) (FETO)

ventilator-induced lung injury, morbidity and mortality rates for babies with congenital diaphragmatic hernia (CDH) remain high. The survival relates to the degree of prenatal lung compression and the

MRI
prenatal
nitric oxide
e 25
fetal therapy
  • 7 views
  • 21 Oct, 2022
  • 1 location