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Found 61 clinical trials
Featured trial
Hyperbaric Oxygen (HBO) Therapy for Traumatic Brain Injury

Hyperbaric Oxygen (HBO) Therapy for Traumatic Brain Injury

  • 25 Mar, 2021
  • 1 location
Ultrasonographic Assessment of Lung Recruitment Maneuvers in Children Undergoing Lengthy Microsurgery Operations (RM)

The aim of this study will be to explore the clinical value of ultrasonic monitoring in the diagnosis of anesthesia-induced atelectasis, the assessment of the effects of lung recruitment, the best positive end-expiratory pressure (PEEP) after RM and in the detection of the point of lung re-collapse after RM in …

  • 04 Mar, 2022
  • 1 location
18F-fluciclovine PET in Metastatic Castration Resistant Prostate Cancer Treated With Life Prolonging Therapies

This is a pilot phase 2 single-arm study, of men with metastatic castration-resistant prostate cancer (mCRPC). Patients will be treated with any of the approved life-prolonging therapies: abiraterone 1000 mg daily plus prednisone 5 mg (or dexamethasone 0.5 mg) daily, enzalutamide 160 mg daily, or docetaxel 50 mg/m2 every two …

luteinizing hormone
neutrophil count
prostate adenocarcinoma
  • 21 Oct, 2021
  • 1 location
Trial of Pembrolizumab in Cancer of Unknown Primary

Abbreviated Title : CUPem Clinical Indication : A Phase II, Two-Stage, Trial of Pembrolizumab in Cancer of unknown primary Trial Type : Single Arm, non-randomised; Two-stage; Hypothesis generating Type of control : None Route of administration : IV Trial Blinding : N/A Treatment Groups :Two cohorts: (i) First Cohort: One …

  • 22 Jan, 2021
  • 1 location
Long-Term Transcutaneous Stimulation and Essential Tremor: A PET Study

Essential tremor (ET) is the most common movement disorder in the United States and affects up to 5% of the population. ET patients experience involuntary shaking of the hands, head and/or voice that can range from mildly limiting to severely disabling. Treatment options are limited and there are currently no …

movement disorder
hand tremor
brain stimulation
  • 17 Mar, 2022
  • 1 location
In-depth Investigation of Brain Network Interactions (BNI)

Brain stimulation is a means to potentially remediate symptoms in a range of neurological and psychiatric diseases, however, precise targeting of stimulation is necessary to ensure efficacy. The proposed project will use recent advances in functional magnetic resonance imaging to delineate distributed brain networks within individuals, and use these network …

  • 23 Mar, 2022
  • 1 location
Methods of Computed Tomography Screening and Management of Lung Cancer

European lung cancer screening studies using computed tomography (CT) have shown that a management protocol based on measuring lung nodule volume and volume doubling time (VDT) is more specific for early lung cancer detection than a diameter-based protocol. However, whether this also applies to a Chinese population is unclear. The …

ct scan
Accepts healthy volunteers
lung cancer screening
lung cancer
  • 10 Feb, 2022
  • 1 location
Promoting Smoking Cessation in Lung Cancer Screening Through Proactive Treatment (PROACT)

This pragmatic trial will evaluate the value of routinely providing proactive smoking cessation support to current smokers as a part of participating in lung cancer screening within Veterans Health Administration.

lung cancer screening
smoking cessation therapy
smoking cessation
lung cancer
  • 14 Feb, 2022
  • 3 locations
DISE: Phenotyping Obstruction Patterns

, deriving functional determinants of upper airway obstruction during sleep. In addition, they will use objective anatomic measurements from computerized tomography (CT) and submental ultrasound. The

  • 02 Dec, 2021
  • 1 location
Dupilumab in CRSsNP (Liberty CRSsNP ORION)

Primary Objective: Part A and B: To evaluate the efficacy of dupilumab as assessed by the reduction at Week 24 in sinus opacification on computerized tomography (CT) scan and sinus total

ct scan
sinus surgery
facial pain
  • 25 May, 2022
  • 48 locations