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Found 7 clinical trials
Impact of Surgical Timing on the Neurodevelopmental Prognosis of Newborns With Complex Congenital Heart Disease (CINC)

We propose a prospective observational study whose main objective will be to determine whether there is an association between age at surgery (days of life) and neurodevelopmental outcome in patients with CCHD. Secondly, we will study the relationship between age at surgery and (i) the incidence of WMI observed on …

  • 10 Aug, 2022
  • 1 location
New Designed ePTFE Valved Conduits for Surgical Reconstruction of Right-ventricular Outflow Tract

Valved conduits used for the reconstruction of right-ventricular outflow tract are applied in the surgical repair of complex congenital heart disease(CHD) such as pulmonary atresia(PA), truncus

tetralogy of fallot
pulmonary insufficiency
complex congenital heart disease
  • 31 Oct, 2021
  • 3 locations
Enhanced External Counterpulsation in Patients With Fontan Circulation

The purpose of the proposed study is to determine the safety of enhanced external counterpulsation (EECP), a system for compressing the blood vessels in the legs in synchrony with an individual's cardiac rhythm, in clinically well, adult Fontan patients, to document the acute hemodynamic and myocardial effects of EECP on …

  • 27 Apr, 2022
  • 1 location
Implementing Models for Mechanical Circulatory Support Presurgical Assessment in Congenital Heart Disease Treatment (IMMPACT)

The purpose of this research study is to look at the advantages of using a 3D printed heart model for surgical planning in children who have been diagnosed with Congenital Heart Disease (CHD) and clinical heart failure and will undergo a ventricular assist device (VAD) placement. The investigators want to …

  • 20 Apr, 2022
  • 9 locations
Noninvasive Measurement of the Cerebral Autoregulation in Neonates and Infants With Complex Congenital Heart Disease

Feasibility of non-invasive cerebral autoregulation measurement at the PICU and impact of changes in oxygen supply

  • 24 May, 2022
  • 1 location
National Collaborative to Improve Care of Children With Complex Congenital Heart Disease (NPC-QIC)

The purpose of this initiative is to improve care and outcomes for infants with HLHS by expanding the NPC-QIC national registry to gather clinical care process, outcome, and developmental data on infants with HLHS between diagnosis and 12 months of age, by improving the use of standards into everyday practice …

  • 23 Feb, 2022
  • 60 locations
Liver Disease, Myocardial Fibrosis and Collaterals in the Adult Fontan Patient - a Metabolomics and Proteomics Approach

Out objective is to identify the mechanisms that promote hepatic and myocardial fibrosis, and collateral vessel formation in patients with complex congenital heart disease and Fontan circulation

Accepts healthy volunteers
  • 18 Sep, 2022
  • 1 location