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Found 52 clinical trials
Neoadjuvant CCRT With/Without Bevacizumab for Locally Advanced ESCC

ESCC. Meanwhile, several prospective clinical studies have shown the feasibility, safety, and activity of adding Bevacizumab to chemotherapy, CCRT, or combined modality therapy including surgery

  • 0 views
  • 23 Jan, 2021
  • 1 location
Neoadjuvant IBI308 Bevacizumab Plus Pemetrexed and Carboplatin Followed by Surgery in Unresectable Stage III NSCLC

The purpose of this study is to studying neoadjuvant IBI308, bevacizumab, plus pemetrexed and carboplatin followed by surgery to see how well it works in treating patients with unresectable stage III non-small cell lung cancer.

  • 0 views
  • 22 Jan, 2021
  • 1 location
A Phase II Study of Combine Modality Therapy in Locally Advanced Pancreatic Cancer

Induction chemotherapy will be administered every 2 weeks for 6 cycles (about 3 months). Patients who have radiological evidence of progressive disease will be shifted to salvage chemotherapy. Patients who have responsive or stable disease after induction chemotherapy will receive concurrent chemoradiotherapy 3-4 weeks after the last dose of induction …

celiac
measurable disease
chemoradiotherapy
oxaliplatin
leucovorin
  • 11 views
  • 07 Nov, 2020
  • 2 locations
Nivolumab After Combined Modality Therapy in Treating Patients With High Risk Stage II-IIIB Anal Cancer

This phase III trial investigates how well nivolumab after combined modality therapy works in treating patients with high risk stage II-IIIB anal cancer. Immunotherapy with monoclonal antibodies

  • 306 views
  • 01 Aug, 2021
  • 724 locations
NEoadjuvant Gefitinib fOllowed by Surgery and gefiTinib In unresectAble sTage III NSCLC With EGFR Mutations.

The purpose of this study is to studying neoadjuvant gefitinib followed by surgery, followed by adjuvant gefitinib to see how well it works in treating patients with unresectable stage III NSCLC harboring EGFR mutations.

stage iii non-small cell lung cancer
gefitinib
EGFR
  • 0 views
  • 22 Jan, 2021
  • 1 location
Safety and Efficacy Study of Nimotuzumab Plus Neoadjuvant and Concurrent Chemoradiotherapy to Treat Oropharynx and Hypopharynx Cancer

The purpose of this study is to evaluate the efficiency and safety of adding nimotuzumab to neoadjuvant and concurrent chemoradiotherapy in the treatment of patients with locoregionally advanced squamous cell carcinoma of the oropharynx and hypopharynx.

docetaxel
cancer
chemoradiotherapy
carcinoma
oropharyngeal squamous cell carcinoma
  • 16 views
  • 08 Nov, 2020
  • 1 location
Comparison Study of Brachytherapy and Endoscopic Stenting for Dysphagia in Esophago-Gastric Junction Cancer

The objective of the study is comparison of the efficacy and safety of palliative therapy with single-dose brachytherapy or selfexpanding metal stents (SEMS) in malignant dysphagia resulting from adenocarcinoma of the esophago-gastric junction.

  • 19 views
  • 07 Nov, 2020
  • 1 location
Central Sleep Apnea : Physiologic Mechanisms to Inform Treatment

Central sleep apnea (CSA) is common in patients with heart failure and those using opioid analgesics. Unfortunately, effective treatment of central apnea remains elusive, pressure therapy given the modest efficiency of positive airway pressure therapy. The focus of this proposal is to identify mechanistic pathways to guide future therapeutic interventions …

  • 0 views
  • 29 Jan, 2021
  • 1 location
The Palliative Benefit of Involved-site Radiotherapy for Patients With Advanced-stage Diffuse Large B-cell Lymphoma

The standard treatment approach for patients with stage III-IV DLBCL is combination chemotherapy. Receipt of consolidation radiotherapy (RT) after effective chemotherapy was associated with improved in-field control and event-free survival. However, it is uncertain for the radiotherapy field size to treat for these patients after chemotherapy. Involved-field radiotherapy (IFRT) after …

b-cell lymphoma
prednisone
vincristine
doxorubicin
cyclophosphamide
  • 32 views
  • 21 Jan, 2021
  • 1 location
Efficacy of Atezolizumab Concurrent With Radiotherapy in Patients With Muscle-invasive Bladder c ncer

Open, multicentre, phase II trial of atezolizumab with concurrent normofractionated radiotherapy in patients with localized muscle-invasive bladder cancer treated with a selective multimodality bladder conservative approach.

bladder tumor
aptt
radical cystectomy
carcinoma
cancer
  • 10 views
  • 01 Aug, 2021
  • 12 locations