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Found 57 clinical trials
Neoadjuvant IBI308, Bevacizumab, Plus Pemetrexed and Carboplatin Followed by Surgery in Unresectable Stage III NSCLC (NIBCUN)

The purpose of this study is to studying neoadjuvant IBI308, bevacizumab, plus pemetrexed and carboplatin followed by surgery to see how well it works in treating patients with unresectable stage III non-small cell lung cancer.

  • 0 views
  • 02 Feb, 2022
  • 1 location
Central Sleep Apnea : Physiologic Mechanisms to Inform Treatment (CSA)

Central sleep apnea (CSA) is common in patients with heart failure and those using opioid analgesics. Unfortunately, effective treatment of central apnea remains elusive, pressure therapy given the modest efficiency of positive airway pressure therapy. The focus of this proposal is to identify mechanistic pathways to guide future therapeutic interventions …

heart failure
opioid
apnea-hypopnea index
Accepts healthy volunteers
central sleep apnea
  • 0 views
  • 23 Mar, 2022
  • 1 location
The Palliative Benefit of Involved-site Radiotherapy for Patients With Advanced-stage Diffuse Large B-cell Lymphoma

The standard treatment approach for patients with stage III-IV DLBCL is combination chemotherapy. Receipt of consolidation radiotherapy (RT) after effective chemotherapy was associated with improved in-field control and event-free survival. However, it is uncertain for the radiotherapy field size to treat for these patients after chemotherapy. Involved-field radiotherapy (IFRT) after …

cyclophosphamide
prednisone
doxorubicin
vincristine
b-cell lymphoma
  • 38 views
  • 21 Jan, 2021
  • 1 location
Efficacy of Atezolizumab Concurrent With Radiotherapy in Patients With Muscle-invasive Bladder cáncer

Open, multicentre, phase II trial of atezolizumab with concurrent normofractionated radiotherapy in patients with localized muscle-invasive bladder cancer treated with a selective multimodality bladder conservative approach.

anticoagulants
radical cystectomy
bladder cancer
carcinoma
atezolizumab
  • 10 views
  • 20 Feb, 2022
  • 10 locations
Efficacy of Consolidative Involved-site Radiotherapy for Patients With Limited-stage Follicular Lymphoma

Radiotherapy (RT) is an important option for patients with limited stage FL. The recommended approach for patients with limited stage FL by The National Comprehensive Cancer Network (NCCN) is 24Gy~30Gy consolidation RT following effective systemic therapy. There is no universal consensus for a ''standard'' RT field size in the treatment …

follicular lymphoma, grade 1
cyclophosphamide
prednisone
vincristine
cancer
  • 46 views
  • 21 Jan, 2021
  • 1 location
Efficacy of Consolidative Involved-site Radiotherapy for Patients With Limited-stage Diffuse Large B-cell Lymphoma

The most common option of radiotherapy for patients with limited-stage DLBCL is involved-field radiotherapy (IFRT). The more limited radiotherapy field size changing from IFRT to reasonable margin from gross tumor has been reported to maintain the high rates of local disease control, while minimizing the risks of radiation-induced toxicities. However, …

cyclophosphamide
prednisone
doxorubicin
vincristine
b-cell lymphoma
  • 14 views
  • 21 Jan, 2021
  • 1 location
Combined Modality Therapy in Hepatoblastoma: South Egypt Cancer Institute Experience

The aim of this study is to retrospectively investigate the effect of combined modality treatment of pediatric hepatoblastoma and the factors affecting the prognosis in accordance with the experience at the pediatric oncology department at South Egypt Cancer Institute.

cancer
  • 27 views
  • 20 Apr, 2022
  • 1 location
Neoadjuvant Carilizumab and Apatinib for Recurrent High-Grade Glioma

GBM is the most common intracranial tumor in adults, accounting for about 40% of all primary intracranial tumors.Although surgery, radiotherapy and chemotherapy have been used, the prognosis of glioma patients is still very poor. The study aim to Evaluate the Safety and efficiency of Using the neoadjuvant therapy with Carilizumab …

  • 0 views
  • 25 Jan, 2021
  • 1 location
Toripalimab Combined With Gemcitabine and Cisplatin Treating Resectable Locally Advanced HNSCC

Head and Neck Squamous Cell Carcinoma (HNSCC) is the most common malignant tumor of the head and neck, accounting for 90% of head and neck malignancies, and 16% to 40% of systemic malignancies. There are 60,000 new cases reported annually worldwide, and the incidence and mortality are increasing year by …

  • 0 views
  • 10 Jul, 2021
  • 1 location
Fluzoparib and Abiraterone in the preSurgery Treatment of Prostate Cancer: FAST Trial

The aim of this study is to evaluate the safety and efficacy of fluzoparib combined with abiraterone in neoadjuvant treatment of patients with high-risk localized prostate cancer. Dr. Yao Zhu from Fudan University Shanghai Cancer Center is the co-leading PI of this study.

  • 0 views
  • 10 May, 2022
  • 1 location