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Found 2455 clinical trials
Role of Pseudomonas Aeruginosa Biofilms in Exacerbations in Patients With Bronchiectasis With and Without Chronic Obstructive Pulmonary Disease

investigators will explore the antimicrobial activity of novel combinations of antibiotics against PA, both in in vitro planktonic cultures and in a biofilm model, and will include testing of antibiotic

  • 0 views
  • 26 Mar, 2021
  • 1 location
An EORTC Study Updating the QLQ-BR23 to BR45

diagnosed with breast cancer. Participants will be enrolled in four groups according to their disease stage (1. local/locally advanced disease, 2. metastatic disease, 3. follow up. Various combinations of

primary cancer
advanced breast cancer
breast cancer
locally advanced breast cancer
combinations
  • 0 views
  • 26 Jan, 2021
  • 1 location
Sepsis in the ICU-II

clinical outcome in sepsis. Therefore, the diagnostic and prognostic value of combinations of clinical, biochemical and haemodynamic variables remains to be established. Accordingly, the purpose of

  • 0 views
  • 27 Jan, 2021
  • 1 location
Immunophenotyping From Blood of Patients Suffering From Chronic Degenerating Joint Diseases and Receiving LDRT

Patients suffering from chronic degenerating diseases are often treated by a plethora of NSAIDs, DMARDs, Biologicals, as well as combinations of these therapeutics. However, many patients are

  • 0 views
  • 04 May, 2021
  • 2 locations
Study of People With HIV Infection Who Have High Viral Loads Despite Combination Antiretroviral Therapy

HIV. People who have been on at least two combinations of ART drugs (including current ART). People whose last two viral loads were greater than 1,000 copies/mL.

HIV Vaccine
viremia
antiretroviral agents
antiretroviral therapy
western blot
  • 5 views
  • 26 Apr, 2021
  • 1 location
Predictors of Response to Neoadjuvant Docetaxel-Carboplatin Chemotherapy for Patients With Stage II and III Triple Negative Breast Cancer

patients (what unfortunately represent > 50% of them). A relevant problem is the differential response to drugs of TN tumors. These tumors are usually treated with multidrug combinations

carcinoma
erbb2
carboplatin
advanced breast cancer
primary tumor
  • 0 views
  • 25 Jan, 2021
  • 1 location
Safety Analysis of Antimicrobial Pharmacotherapy in Intensive Care Unit at Pediatric Hospital

Changes in the metabolic ability of cytochrome P-450 during child development can affect both bioavailability and elimination depending on the involvement of intestinal and hepatic metabolic processes. The age-related variability of cytochrome P-450 isoenzymes in children has been described since 2010. The variability in the development of the activity of …

  • 1 views
  • 04 Apr, 2021
  • 1 location
Nicotine Vapor Specific Sensory Measurement

This trial aims to develop reliable and valid measures of sensory experiences unique to e-cigarette use. Regardless of whether flavorings show evidence of toxicity in a biological sense, they may nonetheless increase harm by other means, such as increasing appeal, decreasing risk perceptions, or masking harshness or irritation that might …

  • 0 views
  • 24 Jan, 2021
  • 1 location
Appropriate Dosing to Optimise Personalised Cancer Treatments

This is a pilot study to assess feasibility of dried blood spot (DBS) samples for pharmacokinetic measurements of targeted anti-cancer drugs in oncology patients such as patients with BRAF-mutant melanoma receiving targeted treatment with BRAF and MEK inhibitors.

KIT
ovarian carcinoma
advanced renal cell carcinoma
carcinoma
BRAF
  • 0 views
  • 25 Jan, 2021
  • 1 location
Biomarkers And Neurological Outcome in Neonates 2

Follow-up of participants of BANON1 study at age of at least 2 years. BANON1 (ClinicalTrials.gov ID: NCT03357250): Validation of biomarkers based on 24 months neuro-developmental outcome data in a human population for their ability to diagnose the severity of neonatal asphyxia. These biomarkers linked to asphyxia have been identified in …

  • 0 views
  • 01 Feb, 2021
  • 13 locations