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Found 2455 clinical trials
Genetic Basis of Immunodeficiency

This study will examine the role of hereditary factors in different forms of severe combined immunodeficiency (SCID). Patients with immunodeficiencies may be eligible for this study. Candidates include: Patients with diminished numbers of T cells or NK cells or both, or Patients with normal T cell and NK cell numbers …

  • 3 views
  • 05 May, 2021
  • 2 locations
Genetic Analysis of Immune Disorders

The purposes of this study are to 1) identify the genes responsible for certain immune disorders, 2) learn about the medical problems they cause, and 3) learn how to predict who is likely to develop these disorders and what the risk is of passing them on to children. The immune …

wbc count
local anesthetic
  • 0 views
  • 28 Jan, 2021
  • 1 location
The Role of Concomitant Diseases in Postoperative Complications Risk Stratification.

Study is conducted to assess the prevalence and structure of comorbidity among patients undergoing abdominal surgery and produce the stratification of the risk of postoperative complications by identifying independent predictors for its development.

  • 65 views
  • 10 Apr, 2021
  • 42 locations
Detection of Genetic Markers of Lung Cancer

The purpose of this research study is to determine the genetic changes and immunologic changes that are involved in the development and progression of lung cancer.

lung metastases
metastasis
cancer
lung cancer
lung carcinoma
  • 12 views
  • 24 Jan, 2021
  • 1 location
Anti-IL6 and Corticosteroid Monotherapy vs Combination in COVID-19

The cytokine storms mediated by over production of proinflammatory cytokines have been observed in a large population of critically ill patients infected with COVID-19. Patients diagnosed with cytokine storms progress to cardiovascular collapse, multiple organ dysfunction and death rapidly. Therefore, early identification, treatment and prevention of the cytokine storms are …

SARS
covid-19
cytokines
pneumonia
interleukin-6
  • 0 views
  • 18 Mar, 2021
  • 1 location
A Study for Post-marketing Surveillance of Azilsartan Medoxomil/Chlorthalidone Fixed Dose Combination (FDC) in the Treatment of Participants With Essential Hypertension in South Korea

The purpose of this study is to evaluate the safety by assessing all serious and non-serious adverse events (AEs), irrespective of relatedness or expectedness, as well as other safety parameters including laboratory values, serious adverse events (SAEs)/serious adverse drug reactions (ADRs), unexpected AEs and ADRs that are not reflected on …

  • 0 views
  • 25 Jan, 2021
  • 1 location
Palbociclib in Combination With Fulvestrant Versus Fulvestrant in Advanced Breast Cancer: A Real-world Study in China

The purpose of this study is to evaluate efficacy and safety of CDK4/6 inhibitor Palbociclib in combination with Fulvestrant versus Fulvestrant in female patients with HR+/HER2- advanced breast cancer in a real world setting in China. Primary study endpoint: progression-free survival (PFS). Secondary study endpoints: overall survival (OS), overall response …

advanced breast cancer
erbb2
tamoxifen
HER2
endocrine therapy
  • 0 views
  • 24 Jan, 2021
  • 1 location
Quality of Life in Chronic Obstructive Pulmonary Disease (COPD) Patients After Switching to Tiotropium Plus Olodaterol Fixed Dose Combination in Greece

The primary objective of this non-interventional study (NIS) is to evaluate changes within 3 months in quality of life according to health status evaluated with the COPD Assessment Test (CAT) in COPD patients who have recently switched (within one week) from tiotropium monotherapy (Spiriva Handihaler) to dual therapy with tiotropium …

  • 0 views
  • 15 Apr, 2021
  • 2 locations
Improving the Early Detection of Lung Cancer by Combining Exosomal Analysis of Hypoxia With Standard of Care Imaging

This project aims to validate exosomal assays that are based on hypoxia detection as potential biomarkers of early detection. The study analysis will determine whether the assay can detect clinical lung cancer at the time of imaging and interval cancers during subsequent follow up. The study aims to establish preliminary …

  • 0 views
  • 26 Jan, 2021
  • 1 location
The BRAVE Study- The Identification of Genetic Variants Associated With Bicuspid Aortic Valve Using a Combination of Case-control and Family-based Approaches.

Bicuspid aortic valve (BAV) is the most common congenital heart anomaly in the general population (1-2% of all individuals). In affected people, the aortic valve (the structure ensuring one way blood flow between the heart's left pumping chamber, the left ventricle and the main body artery, the aorta) consists of …

  • 0 views
  • 25 Jan, 2021
  • 4 locations