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Found 515 clinical trials
Impulse Oscillometry Measurements in Severe Eosinophilic Asthmatics Before and After Anti-IL-5 Factor Initiation

Eosinophilic inflammation in the small airways of patients with severe asthma is considered to be an important marker of disease severity. In clinical trials, treatment with mepolizumab reduces exacerbation rates by almost a half along with modest improvements in symptom scores and forced expiratory volume in 1 s (FEV1) early …

Accepts healthy volunteers
  • 0 views
  • 13 Dec, 2021
  • 1 location
Diagnostic of Chemotherapy Induced Neuropathy in Children

The purpose of this study is to determine the diagnostic accuracy of a newly developed tool (Electrochemical Skin Conductances (ESC) measurement) easy-to-perform, non-invasive, highly reproductible and not requiring specific training, to identify pediatric chemotherapy-induced-peripheral-neuropathies (CIPN). CIPN are a frequent (20 to 75% depending on the drug), early and potentially severe …

bortezomib
taxane
alkaloids
oxaliplatin
vincristine
  • 0 views
  • 15 Dec, 2021
  • 1 location
A Study to Collect Data on the Treatment Pattern of Xarelto + Acetylsalicylic Acid in the Routine Clinical Practice in Patients Who Are Suffering From a Condition That Narrows the Blood Vessels Supplying the Heart and / or a Condition That Most Commonly Narrows the Blood Vessel in the Legs (XATOC)

The study will focus on effectiveness and safety of rivaroxaban (Xarelto) when given together with acetylsalicylic acid (combination therapy) to patients suffering from coronary artery disease

stroke
myocardial infarction
acute coronary syndrome
infarct
  • 0 views
  • 12 Jul, 2022
  • 1 location
A Study of Lenvatinib in Combination With Pembrolizumab in Korean Patients

The purpose of this study is to collect and evaluate the following information in relation to the safety and the efficacy of Lenvatinib in lenvatinib/pembrolizumab combination therapy in the

combination therapy
pembrolizumab
  • 0 views
  • 29 May, 2022
  • 7 locations
COMPERA / COMPERA-KIDS (COMPERA)

In view of the manifold options for mono- and combination therapy that have now emerged for patients with pulmonary (arterial) hypertension (PH/PAH), controlled clinical trials can only provide

endothelin
vascular disease
congenital heart defects
pulmonary disease
endothelin receptor antagonist
  • 46 views
  • 25 Mar, 2022
  • 7 locations
Validation of the Lupus Low Disease Activity State (LLDAS) in the Asia Pacific Region (APLCLLDAS)

) involvement. As there is no effective targeted monotherapy for SLE, patients also suffer severe toxicity from the use of glucocorticoids and broad-spectrum immunosuppressive therapies. Despite combination

glucocorticoids
autoimmune disease
nephritis
immunosuppression
lupus
  • 356 views
  • 08 Jun, 2022
  • 19 locations
First-line Palbociclib and Endocrine Therapy for Patients With HR+/HER2- Advanced Breast Cancer in the Real-world Setting. (PERFORM)

This is a prospective, single-arm, multi-center observational non-interventional study (NIS) in Germany and Austria.

HER2
anastrozole
erbb2
letrozole
exemestane
  • 2 views
  • 10 Jul, 2022
  • 165 locations
Α Prospective Observational Study for the Evaluation of Disease Control and Quality of Life in Patients With Benign PROStatic hyPERplasia Under Fixed Dose combΙnaTion Treatment With Dutasteride and Tamsulosin as Well as Their qualitY of Life (PROSPERITY)

Investigation of the efficacy and safety of the stable combination of dutasteride and tamsulosin (Dinaplex®) in the Greek population as well as the evaluation of the quality of life of patients with benign prostatic hyperplasia (BPH) in treatment with a stable combination of dutasteride and tamsulosin (Dinaplex®)

hyperplasia
tamsulosin
benign prostatic hyperplasia
  • 0 views
  • 24 Jul, 2022
  • 1 location
Real-world Study of Efficacy and Safety of ICIs and TKIs Therapy for HCC

China is a high-risk area of Hepatocellular Carcinoma (HCC). Although Chinese population accounts for 18.4% of the global population, the number of new HCC patients accounting for about half of the global, which seriously threatens the lives and health of the people. The investigators establish multi-center, retrospective research methods, collecting …

TACE
  • 0 views
  • 28 Jun, 2022
  • 1 location
Real-world Study for Patients With Advanced Hepatobiliary Tumors

The investigators design a large sample size study in the real-world to explore whether targeted therapy and immunotherapy can improve the survival, quality of life and drug safety of patients with advanced hepatobiliary tumors, and analyze the correlation between genetic variation and the effectiveness of therapy.

  • 0 views
  • 29 Jun, 2022
  • 1 location