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Found 545 clinical trials
Determining the Impact of Scaling up Mass Testing Treatment and Tracking on Malaria Prevalence in Ghana

Globally, malaria prevalence in 2016 was reported to have increased with 445,000 deaths, 91% of which occurred in sub-Sahara Africa with more than 75% being children. Individuals who carry the malaria parasite can either be symptomatic (showing signs and symptoms) or asymptomatic (without signs and symptoms). Asymptomatic malaria parasitaemia pose …

  • 14 views
  • 24 Jan, 2021
  • 1 location
Novel Combination Therapy for Osteoporosis in Men

or whether it can be more effectively combined to achieve the most benefit? This trial will test a novel combination therapy for osteoporosis in men based on exciting laboratory findings in mice

  • 2 views
  • 27 Jan, 2021
  • 1 location
Combination Therapy (Provigil + Avonex) to Treat Cognitive Problems in MS

MS has been associated with fatigue, attention problems, and a number of cognitive difficulties. There is no treatment approved yet to treat these problems. We hypothesize that the addition of Provigil to an existing immunomodulatory agent (Avonex) will lead to improved fatigue, attention, and overall cognition in MS patients with …

fatigue
avonex
  • 16 views
  • 07 Nov, 2020
  • 1 location
Combination Therapy for First Line Treatment of Advanced Cervical Cancer

This is a single center phase 1 trail to observe safety and efficacy of Paclitaxel plus Cisplatin\Carboplatin, PD-L1 antibody Toripalimab and Anlotinib as first-line regimen to treat the patient with metastatic persistent or recurrent disease after radical surgeryradical platinum-based concurrent chemoradiotherapy or both (Stage IA-IVA).

  • 0 views
  • 22 Sep, 2021
  • 1 location
Combination Therapy With GEN0101 and Pembrolizmub in Advanced Melanoma Patients PIb/PII

This is a multi-center, open-labeled, non-randomized, single arm investigator-initiated trial to evaluate the safety and efficacy of GEN0101 and Pembrolizmub combination in patients with advanced melanoma.

  • 0 views
  • 22 Jan, 2021
  • 7 locations
Combination Therapy With Fecal Microbiota Transplantation and Vedolizumab for Induction of Ulcerative Colitis

The project intends to assess the polygenic burden of rare disruptive mutations in Parkinson's disease (PD) and how they influence the phenotype/pathological heterogeneity of disease.

vedolizumab
enemas
tumor necrosis factor
fecal microbiota transplantation
microbiota
  • 0 views
  • 16 Sep, 2021
  • 1 location
PAD Combination Therapy Followed by Thal/Dex for Relapsed or Refractory Multiple Myeloma

Prospective multicenter phase 2 study using PAD and Thal/Dex combination sequentially.

refractory multiple myeloma
dexamethasone
cell transplantation
velcade
thalidomide
  • 6 views
  • 07 Nov, 2020
  • 1 location
Combination Therapy With Pembrolizumab and sEphB4-HSA in Previously Treated Urothelial Carcinoma

This phase II trial studies how well recombinant EphB4-HSA fusion protein and pembrolizumab work in treating patients with urothelial (bladder) cancer that has spread from the primary site to other places in the body or has come back and does not respond to certain chemotherapy drugs. Combinations of biological substances …

  • 3 views
  • 22 Jan, 2021
  • 2 locations
Combination Therapy With Carfilzomib for the Antibody-Mediated Rejection Diagnosis in Lung Transplantation

The clinical trial is a Phase II open label, single-arm pilot study to evaluate the safety and efficacy of combination therapy with carfilzomib, plasma exchange and intravenous immunoglobulins

  • 2 views
  • 24 Jan, 2021
  • 1 location
A Phase II Trial of Combination Therapy With Celecoxib and Taxotere for the Treatment of Stage D3 Prostate Cancer

The purpose of this clinical trial is to find out the safety and effectiveness as well as patient’s quality of life on the combination of Taxotere and celecoxib on patients with hormone refractory prostate cancer. Celecoxib (Celebrex) is an FDA approved drug to treat arthritis. Taxotere (Docetaxel) is an FDA …

prostate specific antigen
testosterone level
gonadotropin
adenocarcinoma
casodex
  • 51 views
  • 07 Nov, 2020
  • 1 location