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Found 29 clinical trials
Hybrid Versus Non-Hybrid Endoscopic Submucosal Dissection for Colorectal Polyps (SHORT-ESD) (SHORT-ESD)

This proposed trial will randomize 60 patients with a ≥20 mm large colorectal polyp to either undergo hybrid or non-hybrid ESD. For the primary comparison (hybrid vs non-hybrid ESD), the primary

  • 07 Oct, 2022
  • 3 locations
Performance Evaluation of CAD-EYE and SCALE-EYE for Detection, Classification, and Measurement of Colorectal Polyps: a Prospective Study

The investigators hypothesize that the clinical implementation of an AI system is an optimal tool to monitor, audit and improve the detection and classification of polyps during colonoscopy. The purpose of this prospective clinical cohort study is to evaluate the performance of the SCALE-EYE virtual scale for measuring polyp size …

  • 04 Oct, 2022
  • 1 location
Polyp Size Measurement During Real-time Colonoscopy Using the Virtual Scale Function SCALE EYE: Variability and Systematic Differences (SCALE EYE)

Size of colorectal polyps is important to decide on appropriate surveillance intervals and treatment modality, as well as carrying out optical diagnosis strategies. However, polyp size

  • 20 Oct, 2022
  • 1 location
A Phase 1b Study to Evaluate the Efficacy and Safety of JNJ-64251330, a Janus Kinase (JAK) Inhibitor, in Participants With Familial Adenomatous Polyposis

The purpose of this study is to determine the effect of JNJ-64251330 in participants with Familial Adenomatous Polyposis (FAP) on colorectal polyp burden (sum of the polyp diameters).

  • 28 Oct, 2022
  • 16 locations
Cold Snare Endoscopic Mucosal Resection Trial

This study compares different approaches to endoscopic mucosal resection (EMR) of large non-pedunculated colorectal polyps (20mm) in a 2 x 2 randomized design. The first randomization will

colorectal polyps
mucosal resection
  • 10 Jun, 2021
  • 1 location
Effect of Chemoprevention by Low-dose Aspirin of New or Recurrent Colorectal Adenomas in Patients With Lynch Syndrome (AAS-Lynch)

The proposed trial will evaluate the effect of aspirin 300 mg/d and 100 mg/d during 4 years vs placebo, in a 4 groups randomised parallel design in Lynch syndrome patients: patients with proven carriers of pathological mutations in mismatch repairs genes and patients with personal and family history characterizing Lynch …

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  • 08 Jul, 2022
  • 1 location
Efficacy of EndoClot Spraying After Endoscopic Resection of Large Colorectal Polyps

-pedunculated colorectal polyps (20mm) will reduce the risk of delayed bleeding. We hypothesize that EndoClot application will reduce the risk of delayed bleeding by at least 3/4 (i.e. from 7.5% to 1.5%) based

  • 11 Sep, 2021
  • 4 locations
The Effectiveness of Sedation and Analgesia in Colonoscopy Treatment of Colorectal Polyps

This study aims to evaluate the effectiveness of sedation and analgesia in the treament of colorectal polyps by colonoscopy.

  • 04 Jun, 2021
  • 1 location
Effects of UNICLA-A2 Dairy Products on Patients at High-risk of Colorectal Cancer Development

Dietary intervention with UNICLA-A2 milk products containing beta casein A2 protein, and higher levels of omega-3 fatty acids and selenium may contribute to maintain the intestinal integrity, reduce inflammatory processes, normalize the immune system, protect against oxidative damage and equilibrate the gut microbiota in high-risk colorectal cancer patients who have …

  • 07 Oct, 2022
  • 1 location
  • 25 Oct, 2022
  • 1 location