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Found 84 clinical trials
A Phase I Study of Mozobil in the Treatment of Patients With WHIMS

medication called granulocyte colony stimulating factor (G-CSF), and supplemental immunoglobulin (antibody). These therapies are expensive, nonspecific, have significant side effects and toxicities, and do

granulocyte colony stimulating factor
aspermatogenic sterility
HIV Infection
human papillomavirus
  • 20 Sep, 2023
  • 1 location
Treatment and Natural History Study of Lymphomatoid Granulomatosis

beyond a maximum response, with six cycles minimum. To reduce harm to bone marrow, patients receive granulocyte colony stimulating factor (G-CSF), self-administered by injection under the skin daily for

granulocyte colony stimulating factor
cancer chemotherapy
  • 12 Sep, 2023
  • 1 location
Therapeutic Cancer Vaccine (AST-301, pNGVL3-hICD) in Gastric Cancer (Conerstone3)

The purpose of this early proof-of-concept study to evaluate the safety and immunologic efficacy of AST-301 in gastric cancer patients with HER2 expression (including both HER2 low expression and overexpression) who have completed the standard adjuvant treatment (including those who discontinued the standard adjuvant treatment due to intolerance). Participants will …

  • 29 Jul, 2023
  • 2 locations
Treatment of Breakpoint Cluster Region-Abelson (BCR-ABL) Negative ALL in Adults

After consolidation therapy adult patients (≥18 yr) with Ph-negative ALL will be treated with continuation chemotherapy or allogeneic hematopoietic stem cell transplantation (alloHSCT) according to both measurable residual disease (MRD) and results of genetic study performed at baseline.

cell transplantation
residual tumor
consolidation therapy
  • 22 Mar, 2022
  • 14 locations
Microtransplantation Combined With Azacytidine to Improve the Efficacy of EAML

Patients enrolled from each center according to confirmed criteria specified in cooperative scheme are recieved induction and consolidation chemotherapy with microtransplantation . Observe the remission rate and 2-year disease-free survival (DFS) and overall survival(OS) rate.

  • 13 Mar, 2022
  • 1 location
Reduced Intensity Haploidentical Transplantation for the Treatment of Primary or Secondary Myelofibrosis

This phase II trial studies the outcomes of using a JAK inhibitor prior to reduced intensity haploidentical (Haplo) transplantation for the treatment of primary or secondary myelofibrosis (MF). Haplo transplant has been shown to be safe and effective in patients with leukemia and lymphoma who don't have an available sibling …

  • 06 Jun, 2022
  • 1 location
Microtransplantation for Advanced and Relapsed Solid Tumors

In this study, we will apply micro transplantation to the field of solid tumors to study the efficacy and safety of radiotherapy and chemotherapy combined with micro transplantation in the treatment of advanced / relapsed solid tumors.

  • 01 Jul, 2021
211At-BC8-B10 Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed or Refractory High-Risk Acute Leukemia or Myelodysplastic Syndrome

This phase I/II trial studies the side effects and best dose of a radioactive agent linked to an antibody (211At-BC8-B10) followed by donor stem cell transplant in treating patients with high-risk acute leukemia or myelodysplastic syndrome that has come back (recurrent) or isn't responding to treatment (refractory). 211At-BC8-B10 is a …

chronic myelomonocytic leukemia
stem cell transplantation
granulocyte colony stimulating factor
cell transplantation
  • 11 Apr, 2023
  • 1 location
Microtransplantation for Ovarian Cancer

In this study, we will apply micro transplantation to the field of recurrent and advanced ovarian cancer to study the efficacy and safety.

  • 04 Nov, 2021
  • 1 location
Study of NMS-03592088 in Patients With Relapsed or Refractory AML or CMML

The purpose of this study is to explore safety, tolerability, including the maximum tolerated dose, and antitumor activity of NMS-03592088 in adult patients with relapsed or refractory Acute Myeloid Leukemia (AML) or Chronic Myelomonocytic Leukemia (CMML).

chronic myelomonocytic leukemia
flt3 internal tandem duplication
refractory acute myeloid leukemia (aml)
  • 03 Feb, 2022
  • 4 locations