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Found 122 clinical trials
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A 52-week, phase 3, multicentre, randomised, double blind, efficacy and safety study comparing GSK3196165 with placebo and with tofacitinib, in combination with MTX in participants with moderately to severely active RA who have an inadequate response to MTX.

A 52-week, phase 3, multicentre, randomised, double blind, efficacy and safety study comparing GSK3196165 with placebo and with tofacitinib, in combination with MTX in participants with moderately to severely active RA who have an inadequate response to MTX.  

tofacitinib
  • 55 views
  • 23 Nov, 2020
  • 1 location
featured
Antithymocyte Globulin (ATG) and Pegylated Granulocyte Colony Stimulating Factor (GCSF) in New Onset Type 1 Diabetes

Antithymocyte Globulin (ATG) and Pegylated Granulocyte Colony Stimulating Factor (GCSF) in New Onset Type 1 Diabetes

  • 230 views
  • 25 Mar, 2021
  • 1 location
featured
Improved Methods of Cell Selection for Bone Marrow Transplant Alternatives

growth factor. The growth factor (granulocyte colony stimulating factor) is designed to increase the production of donor stem cells. In the second step white blood cell lymphocytes are removed from

  • 194 views
  • 22 Dec, 2020
  • 1 location
featured
Nonmyeloablative Haploidentical Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disease

Background: Peripheral blood stem cell transplantation procedures are used for people with sickle cell disease. Researchers want to improve the success and reduce the complications for these procedures. This might allow more people to have a transplant. Objective: To see if a new transplant regime is effective, safe and well …

cell transplantation
stroke
red blood cell disorder
sickle cell disease
  • 57 views
  • 22 Dec, 2020
  • 1 location
Part II: Granulocyte-Colony Stimulating Factor Adjunct Therapy for Biliary Atresia

The Investigators propose to test the hypothesis that GCSF enhances the clinical outcome of biliary atresia in a multi-institutional Phase 2 trial to prospectively evaluate the safety and efficacy of GCSF in each of the 2 groups of newly diagnosed BA patients: KBA (i.e., Kasai-operated) or NoK (i.e., patients who …

  • 0 views
  • 24 Jan, 2021
  • 3 locations
FLAG+Ida With G-CSF Priming for Patients Younger Than 60 Years With Resistant AML

- To determine the feasibility of fludarabine and cytarabine as continuous infusion plus idarubicin with granulocyte-colony stimulating factor priming for patients with resistant acute

fludarabine
cytarabine
acute promyelocytic leukemia
granulocyte colony stimulating factor
colony stimulating factor
  • 22 views
  • 07 Nov, 2020
  • 1 location
Fludarabine and Cytarabine as Continuous Infusion Plus G-CSF Priming for Elderly Patients With Resistant AML

- To determine the feasibility of fludarabine and cytarabine as continuous infusion plus granulocyte-colony stimulating factor priming for elderly patients with resistant acute

fludarabine
cell transplantation
colony stimulating factor
induction chemotherapy
cytarabine
  • 23 views
  • 07 Nov, 2020
  • 1 location
Trial of Filgrastim Versus Placebo Following Allogeneic Bone Marrow Transplantation

study is to determine the effect of granulocyte colony-stimulating factor [G-CSF] (Neupogen; filgrastim) on the risk of acute GvHD after allogeneic bone marrow transplantation.

cancer
transplant conditioning
anemia
filgrastim
bone marrow transplant
  • 47 views
  • 07 Nov, 2020
  • 1 location
Fractionated Docetaxel and Radium 223 in Metastatic Castration-Resistant Prostate Cancer

The objective of this study is to determine the maximum safe dose of Ra-223 in combination with fractionated (split doses) docetaxel when given to subjects and to determine the best administering dose. The study will look at side effects that may happen while taking the combination treatment. A total of …

  • 8 views
  • 03 Feb, 2021
  • 4 locations
LONsurf and G-CSF Use: Being On A Right Dose-intensity to Optimize Treatment Efficacy

Prospective cohort of patients treated with trifluridine/tipiracil, maximal sample size 250 patients. It is expected, that 89 patients will experience a grade 3-4 neutropenia and will be included in the phase II.

irinotecan
aflibercept
fluoropyrimidine
liver metastasis
bevacizumab
  • 0 views
  • 04 Feb, 2021
  • 19 locations