Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 735 clinical trials
Seven Versus 14 Days of Antibiotic Therapy for Multidrug-resistant Gram-negative Bacilli Infections (BGN)

Antimicrobial resistance is a major global problem, particularly in hospital-acquired infections (HAIs). Gram-negative bacilli (GNB), including Enterobacterales, Pseudomonas aeruginosa, and Acinetobacter baumannii, are among the most common pathogens associated with multidrug resistance and HAIs. These bacteria are of special concern because few therapeutic options are available. Traditionally, the duration of …

severe infection
antibiotics
antimicrobial agent
antimicrobials
bloodstream infection
  • 0 views
  • 24 Mar, 2022
  • 4 locations
Study on the Establishment of a System for Early Warning and Prognostic Evaluation of Patients With Sepsis

Sepsis is a clinical syndrome with high morbidity and high fatality rate in emergency department. Patients with acute liver or kidney injury are more likely to develop Multiple Organ Dysfunction Syndrome(MODS) secondary to the non-hepatic injury group, and the prognosis deteriorates significantly. At present, there is no unified diagnostic criteria …

organ failure
resuscitation
septic shock
shock
Accepts healthy volunteers
  • 0 views
  • 22 Mar, 2022
  • 1 location
Effect of Simvastatin on Sepsis and Febrile Neutropenia in Patients With Acute Lymphoblastic Leukemia

In general, the percentage of complete remissions is 85 - 90 % for acute lymphoid leukemia (ALL). In developing countries, percentages are lower secondary to higher sepsis-related mortality. Although the effect of statins on inflammatory response associated with sepsis has been demonstrated, including an effect on bacterial proliferation in patients …

inflammatory response
cancer
  • 0 views
  • 24 Mar, 2022
  • 1 location
BIA Assessment of Polymyoneuropathy in Critically Ill Patients

The aim of the study is to monitor and evaluate changes in body composition, with a special emphasis on muscle mass, in the context of polyneuromyopathy of critically-ill patients at ICU, on artificial ventilation (duration of artificial ventilation at least 7 days), and subsequent comparison with the patient's condition in …

  • 0 views
  • 13 May, 2021
  • 2 locations
Oral Administration or Nasal Feeding of Huzhangxiefei Decoction for Treatment in Sepsis Induced Acute Lung Injury

Hypothesis 1A: Oral Administration or Nasal Feeding of Huzhangxiefei Decoction will significantly attenuate sepsis-induced systemic organ failure as measured by overall response rate. Hypothesis 1B: Oral Administration or Nasal Feeding of Huzhangxiefei Decoction will attenuate sepsis-induced lung injury as assessed by the respiratory rate and oxygenation index. Hypothesis 1C: Oral …

urine output
acute respiratory distress syndrome
chest x-ray
procalcitonin
pao2
  • 0 views
  • 02 Dec, 2021
  • 1 location
Effect of S-ketamine Anesthetic on Inflammatory Response in Septic Patients Undergoing Abdominal Surgery

This study is a randomized, double-blinded, controlled design. In this study, low doses of S-ketamine were selected for surgury treatment in septic patients under general anesthesia , Meanwhile, activity of HO-1 protein , oxidative stress and inflammatory markers in serum are measured to evaluating the effects of S-ketamine Anesthetic on …

abdominal surgery
inflammatory response
anesthesia
sepsis
  • 0 views
  • 06 Sep, 2021
  • 1 location
DetectIon of Severe Sepsis In PATients With Neurological haemorrhagE (The DISSIPATE Study) (DISSIPATE)

The research study is to explore novel early predictors and validation of laboratory parameters in the management of sepsis in critically ill patients especially with brain injuries and systemic inflammatory response syndrome (SIRS).

procalcitonin
severe sepsis
systemic inflammatory response syndrome
blood culture
inflammatory response
  • 0 views
  • 24 Mar, 2022
  • 1 location
Study of MDW Levels Predicting the Development of Sepsis in Hospitalized HIV-infected Patients and Correlation With Prognosis

Sepsis is a common and critical complication in HIV-infected patients and an important marker of high risk of patient death. The widely used diagnostic criteria for sepsis still have many deficiencies and do not allow for good prediction and timely determination of the onset of sepsis. In HIV-infected patients, abnormal …

HIV Vaccine
  • 0 views
  • 08 Dec, 2021
  • 1 location
Inulin for Infections in the Intensive Care Unit

Normal gut bacteria prevent colonization and subsequent infection with MDR organisms (MDROs) through competition for resources and other mechanisms. During critical illness, this function of the microbiome is lost and there are no current treatments to restore it. Preliminary data indicates that the prebiotic fiber inulin is safe and may …

  • 0 views
  • 27 Jan, 2021
  • 1 location
Acetaminophen and Ascorbate in Sepsis: Targeted Therapy to Enhance Recovery (ASTER)

Prospective multi-center phase 2b randomized placebo-controlled double-blinded interventional platform trial of two different pharmacologic therapies (intravenous Vitamin C or intravenous Acetaminophen) for patients with sepsis-induced hypotension or respiratory failure.

antibiotics
respiratory failure
sepsis
mechanical ventilation
vasopressor
  • 0 views
  • 27 Apr, 2022
  • 8 locations