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Found 730 clinical trials
Mechanistic Inflammatory Sub-study Embedded Within the Albumin vs Balanced Crystalloid Trial (MIS-ABC Sepsis)

MIS-ABC Sepsis is a sub-study looking to understand how the immune response in patients with infection changes during the early stages of the illness, as well as after intravenous fluid treatment. Participants in the main trial will be given one of two types of fluid (Human Albumin Solution (HAS) and …

severe infection
  • 19 Jun, 2022
  • 1 location
Evaluating Tele-Emergency Care in Costs and Outcomes for Rural Sepsis Patients (TELE-Cost)

Sepsis is a life-threatening emergency for which provider-to-provider telemedicine has been used to improve quality of care. The objective of this study is to measure the impact of rural tele-emergency consultation on long-term health care costs and outcomes through decreasing organ failure, hospital length-of-stay, and readmissions.

  • 27 May, 2022
  • 1 location
Prognosis Impact of NSVTs After an AMI (TeVeO Study).

Nowadays, Sudden Cardiac Death (SCD) due to malignant arrhythmias is an important cause of death among acute myocardial infarction (AMI) survivors. Preventive strategies with implantable cardioverter-defibrillators (ICD) are the best clinical option for patients, but associated sociosanitary impact in the National Health Systems and the fact that current implant strategy …

  • 02 Mar, 2021
  • 1 location
Retrospective Analysis of Chest X-ray Severity Scoring System of COVID-19 Pneumonia (RANCH-COVID)

The research will be retrospective, and will include all patients who were admitted during 2020 and 2021 in the COVID-19 ICU of University Hospital Center Osijek due to pneumonia caused by the Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The association of chest x-ray infiltrate evolution with changes in laboratory …

diagnostic procedures
chest x-ray
  • 13 May, 2022
  • 1 location
Repository for Sepsis and Postresuscitation Samples

The objective of this study is to find a new therapeutic strategy by investigating the serial serum samples of patients with sepsis or postresuscitation state.

cardiac arrest
systemic inflammatory response syndrome
  • 26 Mar, 2021
  • 1 location
National Study on Listeriosis and Listeria (MONALISA)

Listeriosis is a foodborne infection responsible for severe disease. Three main forms are described: septicaemia, central nervous system infections and maternal-fetal infections. Available data on the disease, are mostly retrospective and do not provide an accurate picture of the clinical / biological / genetic risk factors for the disease, nor …

  • 30 Jan, 2022
  • 1 location
Myocardial Contrast Echocardiography in Septic Patients

Myocardial microcirculatory alterations may be involved in the pathogenesis of acute cardiac dysfunction or septic cardiomyopathy in septic patients. The investigators study the cardiac function (systolic and diastolic) with two-dimensional echocardiography (TTE), and the myocardial microcirculation with contrast echocardiography (MCE) and sulphur hexafluoride microbubbles Sonovue injection in ICU septic patients.

lactate level
organ failure
  • 25 Jan, 2021
  • 1 location
Effect of CRRT Duration on Solute Removal

The only FDA approved treatment for acute kidney injury(AKI) for patients is Dialysis-also known as renal replacement therapy(RRT). Continuous RRT(CRRT) is the preferred method in the ICU. Patients receiving CRRT with AKI will be recruited to the study where blood and effluent will be collect prior to CRRT initiation and …

replacement therapy
renal injury
acute renal failure
renal replacement
  • 07 Nov, 2021
  • 1 location
The Effect of REcombinant Human Thrombopoietin (rhTPO) on Sepsis Patients With aCUte Severe thrombocytopEnia

The purpose of this study is to determine whether recombinant human thrombopoietin(rhTPO) can rapidly increase the platelets counts, shorten the time of the platelet returned to normal, reduce platelet transfusion and bleeding events, prompt recovery of organ function, decrease the length of ICU stay, and eventually reduce the 28-day mortality …

  • 05 Mar, 2021
  • 1 location
Prevention and Treatment With Calcifediol of COVID-19 Induced Acute Respiratory Syndrome (COVIDIOL)

The administration of Calcifediol in patients with COVID-19, will reduce the development of SARS and the worsening of the various phases of the syndrome. Reducing at least 25% in ICU admission and death from the process, reducing days of hospitalization, facilitating the recovery of the same, acting significantly and positively, …

  • 22 Apr, 2022
  • 1 location