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Found 679 clinical trials
Administration of Antibiotic Prophylaxis for Transperineal Prostate Biopsy in Cipto Mangunkusumo Hospital

This randomized controlled trial aims to compare the rate of perioperative infection complications in transperineal prostate biopsy between the group that receives prophylactic antibiotic and the group that receives placebo. The types of infection studied included bacteriuria, urinary tract infection (UTI), UTI with fever (febrile UTI), and sepsis. This study …

bacteriuria
sepsis
urine culture
fever
trimethoprim-sulfamethoxazole
  • 0 views
  • 12 Aug, 2021
  • 1 location
Plasma Levels of Danger-Associated Molecular Patterns in Young Children After Cardiac Surgery Under Cardiopulmonary Bypass

The investigators have previously reported that cardiac surgery with CPB ( cardiopulmonary bypass) in young infants induced a drastic reduction in mHLA-DR ( Human Leucocyte Antigen) expression, which represents one of innate immune mediator. Danger-Associated Molecular Patterns (DAMPs) can elicit immune response and may subsequentely induce an immune-suppressed state. The …

cardiopulmonary bypass
  • 0 views
  • 22 Sep, 2021
  • 1 location
Bacterial Translocation Markers as Predictors of Infectious and Inflammatory Complications in Acute Bowel Obstruction

Despite modern approaches to the diagnosis and treatment of acute bowel obstruction (ABO), postoperative mortality ranges from 5 to 32%, and complications occur up 23% of cases. One of the formidable infectious and inflammatory complications of ABO is sepsis. The main component of the development of sepsis in ABO is …

cancer
sepsis
  • 0 views
  • 22 Mar, 2022
  • 1 location
Study to Evaluate the Role of Siltuximab in Treatment of Cytokine Release Syndrome (CRS) and Immune Effector Cell Associated Neurotoxicity (ICANS) Related to CAR-T Cell Therapy

This study will evaluate the use of siltuximab to decrease the severity of cytokine release syndrome (CRS) and immune effector cell-associated neurological syndrome (ICANS) in patients who will receive chimeric antigen receptor (CAR) T-cell therapy for the treatment of hematological malignancies.

neutrophil count
lymphoma
follicular lymphoma
multiple myeloma
platelet count
  • 0 views
  • 07 Dec, 2021
  • 1 location
Multiparametric Cardiac MRI in Patients Under CAR T-cell Therapy

Recently chimeric antigen receptor (CAR) T-cell therapy, a new class of chemo therapy, has gained regulatory approval for the treatment of diseases such as B-cell lymphoma. Known side effects include cytokine release syndrome, which has been described to lead to myocarditis, but larger studies exploring this relationship are currently lacking. …

cardiac mri
MRI
lymphoma
chemotherapy regimen
b-cell lymphoma
  • 0 views
  • 06 Jul, 2022
  • 1 location
Dyspnea in Stable Patients With Coronary Artery Disease.

Single-centre prospective study to characterize causes of dyspnea in stable patients with coronary artery disease and evaluate the possibility to determine the cause of dyspnea before in-depth examination.

angiography
angina pectoris
stenosis
arterial disease
myocardial infarction
  • 0 views
  • 04 Sep, 2021
  • 1 location
Scrub Typhus Infection Induced Cardiovascular Disease

Scrub typhus infection has been considered as seasonal and endemic infectious disorder with benign feature. However, the increasing mortality rate of scrub typhus has been recently reported in Southeast Asia and cause of death could be a fetal complicating cardiovascular disease. Therefore, the association and predictors for scrub typhus induced …

cardiovascular disease
  • 9 views
  • 27 Apr, 2022
  • 2 locations
Efficacy and Safety of Selective Digestive Decontamination in the ICU With High Rates of Antibiotic-resistant Bacteria

Secondary infections remain a major cause of mortality in critically ill patients, mainly because of high prevalence of multidrug-resistant microorganisms. Therefore strategies aimed to reduce the incidence of ventilator-associated pneumoniae (VAP) and bloodstream infections are of utmost important. There is robust data on selective digestive decontamination (SDD) efficacy in reduction …

ceftriaxone
vancomycin
oropharyngeal
pneumonia
assisted ventilation
  • 0 views
  • 19 Jun, 2021
  • 1 location
Facilitating Communication Study (FCS2)

This study is a randomized clinical trial of an intervention to improve outcomes for patients and their family by using ICU nurse facilitators to support, model, and teach communication strategies that enable patients and their families to secure care in line with patients' goals of care over an illness trajectory, …

pulmonary disease
cardiac arrest
cognitive impairment
subarachnoid hemorrhage
respiratory distress
  • 590 views
  • 07 Feb, 2022
  • 3 locations
Hysteroscopic Findings in Women Using Progesterone Only Pills (Minipills)

Hysteroscopic findings in women using progesterone only pills (minipills) :A Prospective cohort study.

progesterone
  • 0 views
  • 02 Sep, 2021
  • 1 location