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Found 664 clinical trials
HostDx Sepsis in the Diagnosis and Prognosis of Emergency Department Patients With Suspected Infections and Suspected Sepsis (SEPSIS-SHIELD)

This study will analyze gene expression and other laboratory data from biological samples collected from participants with suspected respiratory, urinary, intra-abdominal, and/or skin & soft tissue infections; or suspected sepsis of any cause.

acute infection
pao2
systolic blood pressure
sepsis
procalcitonin
  • 0 views
  • 16 Jun, 2022
  • 19 locations
Myocardial Injury in Patients With Cardiac Implantable Electronic Devices Undergoing Defibrillation Threshold Testing

Researchers are trying to determine if heart injury occurs in patients with a cardiac implantable electronic device (CIED) who undergo a defibrillation threshold testing (DFT) procedure.

heart injury
myocardial injury
  • 0 views
  • 27 Jul, 2022
  • 1 location
Bacteremia From Periodontal Treatment to Elucidate the Underpinnings of Sepsis

Approximately 40,000 Swedes suffer from sepsiseach year, about 20% die. Biomarkers that are sensitive to current or previous bacteremia are needed in the treatment of sepsis. Bacteremia from periodontal treatment is predictive and occurs in 13-75%. The study's hypothesis is to utilize bacteremia from periodontal treatment to evaluate biological markers …

antimicrobials
antimicrobial agent
Accepts healthy volunteers
bacteremia
antibiotics
  • 2 views
  • 19 Apr, 2022
  • 1 location
A Phase 2 Trial of Anakinra for the Prevention of CAR-T Cell Mediated Neurotoxicity

This research study is studying the combination of anakinra and axicabtagene ciloleucel to reduce the occurrence of the side effects Cytokine Release Syndrome (CRS) and neurologic toxicities with relapsed or refractory Non-Hodgkin lymphoma (NHL). Relapsed NHL is the condition of returned Non-Hodgkin lymphoma. Refractory NHL is the condition of previous …

diffuse large b-cell lymphoma
b-cell lymphoma
refractory non-hodgkin's lymphoma
leukapheresis
lymphoma
  • 0 views
  • 10 Nov, 2021
Low-Dose Dexmedetomidine for Delirium Prevention in Mechanically Ventilated Septic Patients

Delirium is common in septic patients, especially those receiving mechanical ventilation in the intensive care unit (ICU). Dexmedetomidine is a highly selective α2 adrenoreceptor agonist with anxiolytic, sedative, analgesic, and anti-inflammatory effects. Use of dexmedetomidine in mechanically ventilated ICU patients is associated with less delirium and improved outcomes. However, dexmedetomidine …

organ failure
delirium
mechanical ventilation
  • 0 views
  • 03 May, 2022
  • 1 location
Analysis of the Evolution of Mortality in an Intensive Care Unit

The intensive care units is of the main components of modern healthcare systems. Formally, its aim is to offer the critically ill health care fit to their needs; ensuring that this health care is appropriate, sustainable, ethical and respectful of their autonomy. Intensive medicine is a cross-sectional specialty that encompasses …

nitric oxide
arterial blood gases
corticosteroids
assisted ventilation
positive end expiratory pressure
  • 0 views
  • 11 Mar, 2022
  • 1 location
Human Mesenchymal Stem Cells in the Synovial Fluid of the Hip

Previous studies have shown an increase in the concentration of mesenchymal stem cells (MSC's) in the setting of osteoarthritis of the knee and its correlation to severity. Researchers have shown that as there is an increase in the severity of the disease, the concentration of stem cells also increases. The …

collapse
osteoarthritis
core decompression
  • 13 views
  • 02 May, 2022
  • 1 location
The PASTDUe Nutrition Ecosystem Project (PASTDUe) (PASTDUe)

This is a research study to determine if a particular method of providing nutrition improves the clinical outcomes of patients in the intensive care unit (ICU) who have undergone abdominal surgery and would require nutrition delivered via the bloodstream (called total parenteral nutrition or TPN). The nutrition method we are …

abdominal sepsis
abdominal surgery
  • 0 views
  • 26 May, 2022
  • 1 location
Effect of Electroacupuncture in Patients With Sepsis Associated Brain Injury

To investigate the effect of electroacupuncture on patients with sepsis-associated brain injury.

  • 0 views
  • 16 May, 2022
  • 1 location
A Culturally-Based Palliative Care Tele-consult Program for Rural Southern Elders

Rural patients with life-limiting illness are at very high risk of not receiving appropriate care due to a lack of health professionals, long distances to treatment centers, and limited palliative care (PC) clinical expertise. Secondly, although culture strongly influences people's response to diagnosis, illness and treatment preferences, culturally-based care models …

primary cancer
seizures
cancer
  • 40 views
  • 25 May, 2022
  • 2 locations