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Found 285 clinical trials
Study of the Effect of Vedolizumab on Intestinal Microecological Changes and Its Efficacy in the Treatment of Ulcerative Colitis

Inflammatory bowel disease is a group of chronic, non-specific inflammatory diseases of the intestinal tract whose etiology has not yet been fully elucidated, including ulcerative colitis and

antibiotics
inflammatory bowel disease
vedolizumab
monoclonal antibodies
Accepts healthy volunteers
  • 0 views
  • 04 Oct, 2022
  • 1 location
A Phase 3 Study to Investigate the Efficacy and Safety of SHR0302 With Moderately to Severely Active Ulcerative Colitis

Ulcerative Colitis.

anti-tnf-alpha therapy
infliximab
corticosteroids
adalimumab
vedolizumab
  • 0 views
  • 13 Sep, 2023
  • 48 locations
CT to Assess the Efficacy and Safety of Adding GMA to Infliximab in Paediatric Patients With Steroid-refractory Ulcerative Colitis

The primary endpoint will be evaluated through the following variables: PUCAI score, IFX levels, and steroid treatment. Clinical response to IFX will be evaluated through the PUCAI score. The response will be considered clinically significant if PUCAI points continue maintained below 30 during the study period. The IFX response will …

infliximab
steroid therapy
corticosteroids
  • 0 views
  • 30 Jul, 2023
  • 7 locations
A Study to Learn About the Safety, Effects and Pharmacokinetics of Study Medication (PF-07054894) for the Treatment of Ulcerative Colitis

This is a study to learn if the experimental medicine (called PF-07054894) is safe, effective, and how it is processed in adult people with ulcers in the colon.

  • 0 views
  • 19 Sep, 2023
  • 12 locations
A Study to Evaluate Efficacy and Long-term Safety of Oral Ozanimod in Chinese Participants With Moderately to Severely Active Ulcerative Colitis (UC)

The purpose of this study is to evaluate the efficacy and safety of ozanimod compared with placebo in participants with ulcerative colitis (UC) in mainland China and Taiwan. The main study is

  • 0 views
  • 11 Sep, 2023
  • 28 locations
Study of ABBV-668 Oral Capsules to Assess Adverse Events and Change in Disease Activity in Adult Participants With Moderate to Severe Ulcerative Colitis

Ulcerative colitis (UC) is a type of inflammatory bowel disease that causes inflammation and bleeding from the lining of the rectum and colon (large intestine). This study will assess how safe

  • 0 views
  • 12 Sep, 2023
  • 13 locations
A Multicenter, Randomized, Double-blind, Parallel, Placebo-controlled Phase II Clinical Study to Evaluate the Efficacy and Safety of IBI112 in Patients With Moderate to Severe Active Ulcerative Colitis

To evaluate the efficacy of IBI112 induction therapy in patients with moderate and severe active Ulcerative Colitis (UC) to achieve clinical remission.

  • 0 views
  • 14 Oct, 2022
  • 1 location
the Prophylaxis of Recurrent Pouchitis After Fecal Microbiota Transplant in UC With Ileo-anal Anastomosis (POCA)

Ulcerative colitis (UC) is a chronic inflammatory digestive (IBD) disease medically treated with corticosteroids, aminosalicylates, immunomodulators, and biologics. Almost one third of UC

  • 0 views
  • 04 Oct, 2022
Fecal Microbiota Transplantation for C Diff Infection

, malignancy or microscopic colitis) which may have an impact on subject's treatment or response to therapy. Sigmoidoscopy: This method still allows infusion of the stool into a more proximal segment

vancomycin
clostridium difficile toxin
fecal microbiota transplantation
rifaximin
toxic megacolon
  • 3 views
  • 26 Aug, 2021
  • 1 location
Role of Antisecretory Factor in Dihydropyrimidine Treatment of Colorectal Cancer (SALFLADMET)

in Crohns disease, Colitis ulcerosa and carcinoids in adults. SPC-flakes have similar effects but need weeks of administration to emerge. Interestingly from an oncological perspective, provision of

  • 0 views
  • 04 Jun, 2022
  • 1 location