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Found 736 clinical trials
The Impact of Aripiprazole Long-acting on Myelin and Cognition in the Onset of Schizophrenia

The general objective of this interventional study is to explore the impact of long-acting arpiprazole on brain structure, in particular potential neurotrophic effects, neurogenetic and neuroprotective that could counteract the progressive neuronal degeneration inherent in the schizophrenic pathology itself. Each subject will undergo a structured clinical interview to assess the …

psychotic episode
psychotropic drugs
aripiprazole
structured clinical interview
scid
  • 0 views
  • 01 May, 2022
  • 1 location
Cerebral Amyloid Imaging Using Florbetapir (AV-45) (IDEA3)

This study is aimed at examining the interest of amyloid radiotracer Florbetapir (18F-AV-45) for the etiological diagnosis of poststroke cognitive impairment and dementia

amyloid
stroke
cognitive impairment
cognitive assessment
18f-av-45
  • 3 views
  • 24 Jan, 2022
  • 1 location
Patient-Centered NeuroRehabilitation (PCN) (PCN)

As individuals grow older, a number of factors can reduce our cognitive (or thinking) abilities such as "normal" aging, neurodegenerative diseases, and cardiovascular disease. This study will evaluate whether cognitive rehabilitation and transcranial electrical stimulation (TES) can improve cognitive abilities. Cognitive rehabilitation refers to methods that are used to improve …

transcranial direct current stimulation
cognitive rehabilitation
cognitive impairment
neurodegenerative disorders
Accepts healthy volunteers
  • 4 views
  • 27 Jan, 2022
  • 1 location
Effect of Vortioxetine on Cognitive Symptoms in Patients With Schizophrenia

Research goals: Examination of the relationship between the use of vortioxetine and cognitive efficacy in patients with schizophrenia. Examination of the association between the use of vortioxetine and the presence depressive symptoms, physical and social anhedonia in patients with the disease from schizophrenia. Examining the association between vortioxetine use and …

antipsychotics
schizophrenia
risperidone
vortioxetine
  • 0 views
  • 24 Jan, 2021
  • 1 location
Digital Game: A Scale to Evaluate the Perioperative Cognitive Function (MentalPlus®)

INTRODUCTION: Cognitive dysfunction is a frequent adverse event in the postoperative period, especially in elderly patients. The tests commonly used for the detection of postoperative cognitive dysfunction are time-consuming and with variable sensitivity and specificity and difficult routine use. Applying a difficult battery of cognitive tests decreases the viability of …

cognitive impairment
cancer
hypertension
diabetes
postoperative cognitive dysfunction
  • 0 views
  • 03 Mar, 2022
  • 1 location
NeuroCognition After Carotid Recanalization (NIA-SCORE)

Complete occlusion of the Internal carotid artery (ICA) by atherosclerotic disease (COICA) causes approximately 15%-25% of ischemic strokes in the carotid artery distribution. Patients treated with medical therapy have a 7%-10% risk of recurrent stroke per year for any stroke and a 5%-8% risk per year for ipsilateral ischemic stroke …

recurrent strokes
dementia
cognitive impairment
alzheimer's disease
medical therapy
  • 0 views
  • 07 Apr, 2022
  • 1 location
Study to Evaluate the Effects of Single Ascending Oral Doses of ACD856 on Safety, Tolerability and Pharmacokinetics

The SAD design of the study is based on the aim to study safety, tolerability and PK of selected doses of ACD856 in a limited number of healthy volunteers. ACD856 will be administered orally.

Accepts healthy volunteers
  • 0 views
  • 06 Mar, 2022
  • 1 location
Evaluating the Efficacy of Cranial Electrotherapy Stimulation in Mitigating Anxiety-induced Cognitive Deficits

This study investigates the potential of cranial electrotherapy stimulation to mitigate anxiety induced cognitive deficits

Accepts healthy volunteers
  • 0 views
  • 24 Mar, 2022
  • 1 location
A Study to Evaluate the Effects of SAGE-718 in Participants With Parkinson's Disease Cognitive Impairment

The primary purpose of this study is to evaluate the effect of SAGE-718 on cognitive performance in participants with Parkinson's disease mild cognitive impairment (PD-MCI).

  • 0 views
  • 16 Jun, 2022
  • 1 location
Augmentation of Working Memory Training With Transcranial Direct Current Stimulation in Patients With Schizophrenia

Cognitive impairment is a core symptom of schizophrenia and is in a large part responsible for the poor psychosocial outcome of the disorder. The use of non-invasive brain stimulation techniques as a therapeutic option is just commencing for neuropsychiatric patients. Concerning healthy subjects the investigators have previously shown that anodal …

schizoaffective disorder
transcranial direct current stimulation
antipsychotics
memory training
cognitive impairment
  • 2 views
  • 24 Apr, 2022
  • 2 locations