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Found 735 clinical trials
SONOlysis in Prevention of Brain InfaRctions During Internal Carotid Endarterectomy (SONOBIRDIE)

SONOBIRDIE Trial is a randomized, single-blind, sham-controlled study designed for a demonstration of the safety and effectiveness of sonolysis (continual transcranial Doppler (TCD) monitoring) in reduction of risk of stroke or transient ischemic attack (TIA), brain infarctions and cognitive decline using a 2-MHz diagnostic probe with a maximal diagnostic energy …

ischemic attack
carotid artery stenosis
  • 02 May, 2022
  • 1 location
Hearing Aid and Individuals With Cognitive Disorders

This is a pilot study with the aim of evaluating the feasibility of the procedures of a future clinical trial that will help determine the impacts of hearing aid interventions on older patients with Alzheimer's Disease and related dementias (ADRD). In this pilot study individuals with mild or moderate cognitive …

  • 27 Apr, 2022
  • 2 locations
Prospective Monocentric Study of Taste in Patients With Minor or Major Cognitive Disorders Such as Alzheimer's Through the Analysis of Gustatory Evoked Potentials.

Approximately 24 million people worldwide suffer from dementia, with Alzheimer's disease being the most common cause. Alzheimer's disease typically progresses in three stages: presymptomatic, prodromal ("early onset" or minor cognitive impairment) and major cognitive impairment with loss of autonomy and significant psycho-behavioral symptoms. Efforts to counteract its expansion are increasing, …

  • 04 May, 2021
  • 1 location
Clinical Trial of Efficacy and Safety of MMH-MAP in the Treatment of Cognitive Disorders in Patients With Ischemic Stroke in the Carotid Arteries

The clinical trial to valuate efficacy and safety of MMH-MAP in the treatment of cognitive disorders in patients with ischemic stroke in the carotid arteries.

  • 30 Apr, 2022
  • 17 locations
Effects of Neurofeedback in Cognitive Deficit in Patients With TBI

with post-traumatic cognitive deficits. Purpose: To assess the effects of low resolution tomography (LoRETA) Z -score neurofeedback (NF) and theta/beta NF in alleviating cognitive impairments in

cognitive rehabilitation
cns stimulants
cognitive deficits
traumatic brain injury
cognitive impairment
  • 25 Mar, 2022
  • 4 locations
Accelerated Neuromodulation to Alleviate Cognitive Deficits Due to Cancer Therapy

This project is aimed at the discovery of neuro-modulation techniques that may alleviate chemotherapy induced cognitive deficits (CICD), especially in executive (higher-order) cognitive function

cancer diagnosis
primary cancer
  • 29 Jul, 2021
  • 1 location
Corticosteroids in Community Acquired Pneumonia

This is a single-center, blinded, placebo-controlled pilot RCT evaluating corticosteroids for the treatment of Community Acquired Pneumonia (CAP) that will enroll 100 adults hospitalized with community-acquired pneumonia. The primary goal is to assess the feasibility of proposed trial procedures for use in a subsequent phase III trial powered on 6-month …

  • 27 Jan, 2021
  • 1 location
Assessment and Rehabilitation of Social Cognition in People With Traumatic Brain Injury

Patients who have suffered moderate to severe traumatic brain injury (TBI) frequently develop behavioural changes, which can have deleterious consequences on interpersonal relationships, social, family and professional reintegration. They are a source of difficulties (burden) for family and friends. Social cognition covers four functions: recognition of social cues; empathy; attribution …

  • 26 Jan, 2021
  • 4 locations
Cognitive Exercises in Survivors of a Prolonged ICU Stay.

This study concerns patients who survived intensive care, after a minimum stay of 7 days and presenting cognitive disorders (with a score 26 on the MoCA test) during the post-intensive care

  • 17 Nov, 2021
  • 1 location
The Impact of Aripiprazole Long-acting on Myelin and Cognition in the Onset of Schizophrenia

The general objective of this interventional study is to explore the impact of long-acting arpiprazole on brain structure, in particular potential neurotrophic effects, neurogenetic and neuroprotective that could counteract the progressive neuronal degeneration inherent in the schizophrenic pathology itself. Each subject will undergo a structured clinical interview to assess the …

psychotropic drugs
psychotic episode
structured clinical interview
  • 01 May, 2022
  • 1 location