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Found 87 clinical trials
Featured trial
Depression

proven to be effective in MDD research studies include antidepressant medications, cognitive behavior therapy, and TMS (transcranial magnetic stimulation). Treatments don't work for all people. Treatments

depressive disorder
depressive symptoms
suicidal
depressed mood
transcranial magnetic stimulation
  • 137 views
  • 30 Jul, 2021
  • 1 location
Group ("Project Life Force") vs. Individual Suicide Safety Planning RCT (PLF)

intervention, combines cognitive behavior therapy (CBT)/dialectical behavior therapy (DBT) skill based, and psychoeducational approaches, to maximize suicide safety planning development and implementation

suicide prevention
behavior therapy
  • 88 views
  • 11 Jul, 2022
  • 2 locations
Valuation in Depressed Mood, Anhedonia, and Anxiety

This study examines how people respond to rewards and losses, and the extent to which these responses are linked or distinct among people experiencing depressed mood, anhedonia, and/or anxiety.

  • 0 views
  • 02 Jun, 2022
  • 1 location
Identification of Biomarkers for Stress Vulnerability and Resilience

The purpose of this research study is to understand the biological mechanisms of stress vulnerability (being susceptible to stress) and stress resilience (being able to recover readily from stress), obtain biomarkers (a biological indicator) for stress resilience and to devise strategies for prevention and treatment of stress-related disorders.

Accepts healthy volunteers
  • 0 views
  • 07 Oct, 2022
  • 1 location
Mechanisms of Change in Cognitive Behavioral Therapy for Insomnia (CBTi) (CBTi)

The purpose of this study is to investigate the mechanisms of change in Cognitive Behavioral Therapy for insomnia (CBTi) in a sample of adults aged 50-65. This study aims to evaluate the pre-post treatment change in sleep, circadian rhythms, biomarkers, cognitive performance, and structural and functional magnetic resonance imaging scans …

cognitive behavioral therapy for insomnia
behavior therapy
  • 0 views
  • 14 Mar, 2022
  • 1 location
Pioglitazone as an Adjunct to Cognitive-Behavioral Therapy for Cocaine Relapse Prevention

The purpose of this study is to see how well pioglitazone, when used with cognitive behavioral therapy, works at helping people who have recently stopped using cocaine to continue to not use cocaine.

  • 0 views
  • 16 Jun, 2022
  • 1 location
Improvement of Cocaine Use Disorder Treatment Through Cognitive Behavioral Therapy Web-based Treatment (CBT4CBT)

Addictions are among the most serious and expensive public health problems in Europe and Spain and they present high morbimortality. There is an increasing amount of studies emphasizing the role e-health for improving current treatments in mental health but research in addictions is still scarce. Over the last years, there …

  • 0 views
  • 14 Jun, 2022
  • 1 location
Dormir Mejor Study: Randomized Controlled Trial of a Culturally Adapted Digital Program of Cognitive-Behavioral Therapy for Insomnia for Spanish Speaking Latina/o Primary Care Patients

The primary objective of the proposed study is to examine the effectiveness of a culturally adapted digital program of cognitive behavioral therapy for insomnia (CBT-I) compared to minimally enhanced usual care (mEUC) on primary outcomes: reduction in insomnia symptoms at 9 weeks and 6 months post-intervention, using a standard scale …

cognitive behavioral therapy for insomnia
chronic insomnia
sleep disturbances
behavior therapy
  • 0 views
  • 13 Oct, 2022
  • 1 location
CBT-ENDURE: Cognitive Behavioral Therapy Following Esketamine for Major Depression and Suicidal Ideation for Relapse Prevention (ENDURE)

This is a rater-blinded, randomized controlled trial. All patients will receive esketamine for treatment of Major Depression with Suicidal Ideation (MDSI). Subjects will be randomized (1:1) to receive CBT (computer-assisted) or TAU alone following esketamine.

  • 0 views
  • 12 Oct, 2022
  • 2 locations
AI-Based Fidelity Feedback to Enhance CBT (AFFECT)

This study is being conducted together by researchers at the University of Pennsylvania and Lyssn.io, Inc., ("Lyssn"), a technology start-up developing digital tools to support evidence-based psychotherapies (EBPs) for mental health disorders and addiction. This study will implement a technology to assess and enhance the quality of EBPs like Cognitive …

Accepts healthy volunteers
  • 0 views
  • 11 Apr, 2023