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Found 16 clinical trials
Implication for Strategies of Long Term Control of Viral Replication in Patient With Primary HIV Infection (PHI).

in a ratio 10:10:8 to be treated with one of the three antiretroviral regimens: TDF/FTC 245 mg/200 mg single tablet QD + DRV /cobicistat 800 mg /150 mg single tablet QD (Arm A

  • 0 views
  • 24 Jan, 2021
  • 1 location
Switch to Genvoya Followed by HCV Therapy With Epclusa Followed by Simplification of HIV Therapy With Biktarvy in Patients With HIV-HCV Co-Infected Subjects on Opioid Substitution Therapy

RNA viral load on current antiretroviral therapy to elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide (E/C/F/TAF, Genvoya) followed by 12 weeks of HCV antiviral therapy with sofosbuvir

opioid substitution
elisa
methadone
opiate substitution treatment
opioid
  • 67 views
  • 23 Jan, 2021
  • 1 location
Convalescent Plasma Therapy vs. SOC for the Treatment of COVID-19 in Hospitalized Patients

A total of 278 patients are planned. All patients will be in an early-stage of COVID-19. They must be adults and hospitalized. In this study, all participating patients will receive the standard treatment provided according to the current treatment protocols for coronavirus disease. In addition to this treatment, each patient …

oropharyngeal
SARS
cough
plasma transfusion
coronavirus infection
  • 187 views
  • 02 Feb, 2021
  • 37 locations
Pharmacokinetics of Antiretroviral Agents in HIV-infected Pregnant Women.

Due to the potential for pregnancy-induced changes in the pharmacokinetics of medication, one cannot assume that the currently licensed doses of the medication to be tested under this protocol lead to adequate exposure in an HIV-infected pregnant woman. For the agents under study no or limited pharmacokinetic data during pregnancy …

haart
antiretroviral agents
hiv antibodies
antiretroviral
immune globulin
  • 156 views
  • 26 Jan, 2021
  • 25 locations
Antiretroviral Pregnancy Registry (APR): Multi-sponsor Registry to Detect Any Major Teratogenic Effect Involving Any of the Registry Drugs When Administered to Pregnant Women.

The purpose of the Antiretroviral Pregnancy Registry (Registry) is to detect any major teratogenic effect involving any of the Registry drugs when administered to pregnant women. Registration is voluntary and confidential with information obtained from the health care provider. A Registry-assigned identifier allows for follow-up capability. Information on subjects is …

prenatal
antiretroviral
hepatitis
antiretrovirals
HIV Vaccine
  • 66 views
  • 25 Jan, 2021
  • 1 location
COVID-19 - Cytokine Storm

This is a multi-center study comparing clinical outcomes in patients with COVID-19 in subjects hospitalized at Hadassah and other hospitals for PCR or serology confirmed COVID-19 and compare the outcomes to the presence of different degrees of a cytokine storm. The patients will be subdivided into a mild, moderate, and …

covid-19
hypercytokinemia
SARS
cytokine storm
  • 0 views
  • 26 Jan, 2021
  • 1 location