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Found 101 clinical trials
CSF Analysis in EGFR Mutant Non-Small Cell Lung Cancer With Leptomeningeal Disease

molecular characterization of central nervous system disease may differ from disease outside of the central nervous system. The aim of this pilot trial is to evaluate for molecular differences between

EGFR
lung carcinoma
systemic therapy
  • 0 views
  • 04 Oct, 2022
  • 1 location
Effect of Olfactory Training on Olfactory Dysfunction Patients in Hong Kong Population

treated by nasal surgery Sensorineural causes included post-infection, post-head injury, post Head and Neck irradiation and other central nervous system diseases. Olfactory

  • 0 views
  • 21 Oct, 2022
  • 1 location
Cognitive Training in Survivors of Covid-19: A Randomized Trial

Coronaviridaes (CoVs) have been associated with central nervous system (CNS) diseases such as acute viral encephalopathy, acute disseminated encephalomyelitis, and multiple sclerosis (6-11).The possible brain

  • 0 views
  • 29 Dec, 2021
  • 1 location
Trial to Evaluate Efficacy and Safety of Bortezomib in Patients With Severe Autoimmune Encephalitis (Generate-Boost)

Autoimmune Encephalitis is a disorder of the central nervous system caused by bodily substances, called antibodies. Antibodies normally help the body to prevent infections. However, in this

  • 5 views
  • 04 Oct, 2022
  • 2 locations
HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors

This study is a clinical trial to determine the safety of inoculating G207 (an experimental virus therapy) into a recurrent or refractory cerebellar brain tumor. The safety of combining G207 with a single low dose of radiation, designed to enhance virus replication, tumor cell killing, and an anti-tumor immune response, …

cancer
biological factors
g207
biologic agent
nitrosourea
  • 84 views
  • 04 Oct, 2022
  • 1 location
ChariotMS - Cladribine to Halt Deterioration in People With Advanced Multiple Sclerosis (ChariotMS)

MS is a chronic inflammatory and degenerative disease of the central nervous system (CNS) affecting more than 120,000 people in the UK.and 2.5 million people worldwide. Without disease

  • 0 views
  • 30 Jun, 2022
  • 16 locations
MRI Study of the Mechanisms Underlying Irreversible Disability in Multiple Sclerosis (SEP-MRI)

disease of the central nervous system. Recently, MRI technics have demonstrated their sensibility to the different processes involved in MS. Particularly, MRI has evidenced that the pathological process

disease or disorder
MRI
cognitive deficits
demyelination
nervous
  • 14 views
  • 04 Oct, 2022
  • 1 location
[18F]F-DOPA Imaging in Patients With Autonomic Failure

distinguish between patients with PD, MSA, and DLB, which may provide vital information to predict conversion from peripheral to central nervous system disease.

pure autonomic failure
dementia
nervous system disorder
multiple system atrophy
Accepts healthy volunteers
  • 19 views
  • 01 May, 2022
  • 1 location
"Evaluation of Usability and Safety of the Self-balancing Walking System Atalante in Patients With Multiple Sclerosis" (EXO)

Multiple sclerosis (MS) is the most prevalent chronic inflammatory disease of the central nervous system (CNS), affecting more than 2 million people worldwide,1 it is a degenerative disease that

disease or disorder
nervous
chronic inflammatory disease
spasticity
fatigue
  • 0 views
  • 20 Oct, 2022
  • 1 location
Phase 2 Study of Alisertib Therapy for Rhabdoid Tumors (SJATRT)

This study incorporates alisertib, the small-molecule inhibitor of Aurora A activity, in the treatment of patients younger than 22 years of age. Patients with recurrent or refractory AT/RT or MRT will receive alisertib as a single agent. Patients with newly diagnosed AT/RT will receive alisertib as part of age- and …

  • 78 views
  • 04 Oct, 2022
  • 9 locations