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Found 102 clinical trials
ALL SCTped 2012 FORUM Add-on Study Blina Post HSCT

A phase II trial of continuous intravenous infusion of Blincyto given over a 28-day cycle. Starting day for patients who are MRD-positive before HSCT is between day +60 and day +100 and for patients who become MRD-positive post HSCT it is between day +60 and day +360 post HSCT. Patients …

  • 19 Mar, 2021
  • 14 locations
A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations

This phase III trial compares standard chemotherapy to therapy with liposome-encapsulated daunorubicin-cytarabine (CPX-351) and/or gilteritinib for patients with newly diagnosed acute myeloid leukemia with or without FLT3 mutations. Drugs used in chemotherapy, such as daunorubicin, cytarabine, and gemtuzumab ozogamicin, work in different ways to stop the growth of cancer cells, …

blast cells
adult acute myelogenous leukemia
cell transplantation
  • 10 May, 2022
  • 98 locations
Power Training Combined With Interval Treadmill Training (PT³)

Ambulatory children with cerebral palsy (CP) experience walking limitations which negatively influence their ability to physically participate in day to day life. The investigators propose that impaired muscle power generation is the key limiting factor affecting walking activity and participation. This proposal represents a combined approach where participants undergo resistance …

resistance training
spastic cerebral palsy
cerebral palsy
cerebral palsy (cp)
  • 12 Feb, 2022
  • 2 locations
Digital Mirror Therapy With Uni- and Bilateral Mirror Visual Feedback After Stroke: Treatment Effects and EEG Evidence

The specific study aims will be: To examine the treatment effects of a new digital mirror therapy (MT) system versus a mirror box in patients with stroke by conducting a 4-group randomized controlled trial. To examine the electrophysiological mechanisms of uni-mirror visual feedback (uni-MVF) condition with unimanual training mode, uni-MVF …

  • 02 Dec, 2021
  • 2 locations
Effect of the Visual Information Change in Functional Dystonia (PRISMADYS)

Cervical dystonia occurring only during the writing task is a rare form for which there is no established treatment. Many authors agree that alteration of sensory integration is associated with dystonia. Similar disturbances in the integration of oculomotor information could have a role in cervical dystonia forms involving visuo-cervico-manual coordination …

sensory integration
movement disorder
nuchal pain
orthoptic treatment
  • 04 Oct, 2022
  • 1 location
For Patients With Ischemic Stroke, Clinically Study the Effectiveness and Safety of Butylphthalide.

This is a prospective, open, single-arm, the real world of clinical trials. The researchers plan to recruit 300 eligible patients. The main purpose of this study is to evaluate the effectiveness and safety of butylphthalide in the treatment of ischemic stroke, and to establish a population pharmacokinetic model of butylphthalide …

  • 30 May, 2022
  • 1 location
Comparison of Transcutaneous and Epidural Spinal Stimulation for Improving Function

Incomplete spinal cord injuries (SCI) are the most frequent neurologic category, comprising 66.7% of all SCI cases. People with incomplete SCI may retain some ability to move the legs and therefore the capacity to regain walking. Studies that show functional improvement in locomotion via electrical stimulation of lumbosacral circuits suggest …

gait training
spinal cord
chronic pain
cardiopulmonary disease
  • 14 Feb, 2022
  • 1 location
Brain Connections for Arm Movement After Stroke (CAM)

The purpose of this study is to use Transcranial Magnetic Stimulation (TMS) while subjects are making reaching movements in a robotic arm device in order to discover how different brain areas control movement before and after stroke and when these brain areas are most sensitive to TMS.

transcranial magnetic stimulation
Accepts healthy volunteers
  • 17 Jun, 2022
  • 1 location
Spinal Cord Stimulation for Restoration of Arm and Hand Function in People With Subcortical Stroke

The goal of this study is to verify whether electrical stimulation of the cervical spinal cord can activate muscles of the arm and hand in people with hemiplegia following stroke. Participants will undergo a surgical procedure to implant a system which provides epidural electrical stimulation (EES) of the cervical spinal …

hemorrhagic stroke
spinal cord
electrical stimulation
  • 04 Oct, 2022
  • 1 location
Role and Mechanism of Probiotics in Improving Motor Symptoms in Mild to Moderate Parkinson's Disease

This study is a multicenter randomized double-blind placebo-controlled study. The research content is 1. The improvement effect of Bifidobacterium triple viable capsulesBIFICO on motor symptoms and constipation and sleep in mild to moderate Parkinson's disease and the safety of the study; 2. the mechanism of the improvement effect of intestinal …

motor symptoms
Accepts healthy volunteers
  • 25 Jan, 2022
  • 1 location